KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NUSAP1
Full Name:
Nucleolar and spindle-associated protein 1
Alias:
Nucleolar and spindle-associated protein 1: Nucleolar and spindle-associated protein 1: Nucleolar and spindle-associated protein 1: Nucleolar and spindle-associated protein 1: Nucleolar and spindle-associated protein 1
Type:
Cell cycle regulation
Mass (Da):
49452
Number AA:
441
UniProt ID:
Q9BXS6
International Prot ID:
IPI00000398
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0000070
GO:0000226
GO:0000281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
P
S
L
E
E
L
D
S
L
K
Y
S
D
L
Q
Site 2
S15
E
L
D
S
L
K
Y
S
D
L
Q
N
L
A
K
Site 3
S23
D
L
Q
N
L
A
K
S
L
G
L
R
A
N
L
Site 4
T33
L
R
A
N
L
R
A
T
K
L
L
K
A
L
K
Site 5
S57
G
N
E
N
Q
D
E
S
Q
T
S
A
S
S
C
Site 6
S60
N
Q
D
E
S
Q
T
S
A
S
S
C
D
E
T
Site 7
S62
D
E
S
Q
T
S
A
S
S
C
D
E
T
E
I
Site 8
T67
S
A
S
S
C
D
E
T
E
I
Q
I
S
N
Q
Site 9
S72
D
E
T
E
I
Q
I
S
N
Q
E
E
A
E
R
Site 10
T88
P
L
G
H
V
T
K
T
R
R
R
C
K
T
V
Site 11
T94
K
T
R
R
R
C
K
T
V
R
V
D
P
D
S
Site 12
S101
T
V
R
V
D
P
D
S
Q
Q
N
H
S
E
I
Site 13
S106
P
D
S
Q
Q
N
H
S
E
I
K
I
S
N
P
Site 14
S111
N
H
S
E
I
K
I
S
N
P
T
E
F
Q
N
Site 15
S124
Q
N
H
E
K
Q
E
S
Q
D
L
R
A
T
A
Site 16
T130
E
S
Q
D
L
R
A
T
A
K
V
P
S
P
P
Site 17
S135
R
A
T
A
K
V
P
S
P
P
D
E
H
Q
E
Site 18
S148
Q
E
A
E
N
A
V
S
S
G
N
R
D
S
K
Site 19
S149
E
A
E
N
A
V
S
S
G
N
R
D
S
K
V
Site 20
S154
V
S
S
G
N
R
D
S
K
V
P
S
E
G
K
Site 21
S158
N
R
D
S
K
V
P
S
E
G
K
K
S
L
Y
Site 22
S163
V
P
S
E
G
K
K
S
L
Y
T
D
E
S
S
Site 23
Y165
S
E
G
K
K
S
L
Y
T
D
E
S
S
K
P
Site 24
T166
E
G
K
K
S
L
Y
T
D
E
S
S
K
P
G
Site 25
S169
K
S
L
Y
T
D
E
S
S
K
P
G
K
N
K
Site 26
S170
S
L
Y
T
D
E
S
S
K
P
G
K
N
K
R
Site 27
T181
K
N
K
R
T
A
I
T
T
P
N
F
K
K
L
Site 28
T182
N
K
R
T
A
I
T
T
P
N
F
K
K
L
H
Site 29
Y202
E
M
E
S
I
D
Q
Y
I
E
R
K
K
K
H
Site 30
S215
K
H
F
E
E
H
N
S
M
N
E
L
K
Q
Q
Site 31
T231
I
N
K
G
G
V
R
T
P
V
P
P
R
G
R
Site 32
S240
V
P
P
R
G
R
L
S
V
A
S
T
P
I
S
Site 33
S243
R
G
R
L
S
V
A
S
T
P
I
S
Q
R
R
Site 34
T244
G
R
L
S
V
A
S
T
P
I
S
Q
R
R
S
Site 35
S247
S
V
A
S
T
P
I
S
Q
R
R
S
Q
G
R
Site 36
S251
T
P
I
S
Q
R
R
S
Q
G
R
S
C
G
P
Site 37
S255
Q
R
R
S
Q
G
R
S
C
G
P
A
S
Q
S
Site 38
S260
G
R
S
C
G
P
A
S
Q
S
T
L
G
L
K
Site 39
S262
S
C
G
P
A
S
Q
S
T
L
G
L
K
G
S
Site 40
T263
C
G
P
A
S
Q
S
T
L
G
L
K
G
S
L
Site 41
S269
S
T
L
G
L
K
G
S
L
K
R
S
A
I
S
Site 42
S273
L
K
G
S
L
K
R
S
A
I
S
A
A
K
T
Site 43
S276
S
L
K
R
S
A
I
S
A
A
K
T
G
V
R
Site 44
S285
A
K
T
G
V
R
F
S
A
A
T
K
D
N
E
Site 45
T288
G
V
R
F
S
A
A
T
K
D
N
E
H
K
R
Site 46
S296
K
D
N
E
H
K
R
S
L
T
K
T
P
A
R
Site 47
T298
N
E
H
K
R
S
L
T
K
T
P
A
R
K
S
Site 48
T300
H
K
R
S
L
T
K
T
P
A
R
K
S
A
H
Site 49
S305
T
K
T
P
A
R
K
S
A
H
V
T
V
S
G
Site 50
T309
A
R
K
S
A
H
V
T
V
S
G
G
T
P
K
Site 51
S311
K
S
A
H
V
T
V
S
G
G
T
P
K
G
E
Site 52
T314
H
V
T
V
S
G
G
T
P
K
G
E
A
V
L
Site 53
T323
K
G
E
A
V
L
G
T
H
K
L
K
T
I
T
Site 54
T328
L
G
T
H
K
L
K
T
I
T
G
N
S
A
A
Site 55
S333
L
K
T
I
T
G
N
S
A
A
V
I
T
P
F
Site 56
T338
G
N
S
A
A
V
I
T
P
F
K
L
T
T
E
Site 57
T344
I
T
P
F
K
L
T
T
E
A
T
Q
T
P
V
Site 58
T347
F
K
L
T
T
E
A
T
Q
T
P
V
S
N
K
Site 59
T349
L
T
T
E
A
T
Q
T
P
V
S
N
K
K
P
Site 60
S352
E
A
T
Q
T
P
V
S
N
K
K
P
V
F
D
Site 61
S363
P
V
F
D
L
K
A
S
L
S
R
P
L
N
Y
Site 62
S365
F
D
L
K
A
S
L
S
R
P
L
N
Y
E
P
Site 63
Y370
S
L
S
R
P
L
N
Y
E
P
H
K
G
K
L
Site 64
Y388
G
Q
S
K
E
N
N
Y
L
N
Q
H
V
N
R
Site 65
Y403
I
N
F
Y
K
K
T
Y
K
Q
P
H
L
Q
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation