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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNF17
Full Name:
RING finger protein 17
Alias:
FLJ11045; Mmip-2; SPATA23; Spermatogenesis associated 23; TDRD4; Tudor domain containing 4; Tudor domain-containing protein 4
Type:
Uncharacterized
Mass (Da):
184643
Number AA:
1623
UniProt ID:
Q9BXT8
International Prot ID:
IPI00005061
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0016788
GO:0003676
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0007283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
A
E
A
S
K
T
G
P
S
R
S
Site 2
T8
M
A
A
E
A
S
K
T
G
P
S
R
S
S
Y
Site 3
S11
E
A
S
K
T
G
P
S
R
S
S
Y
Q
R
M
Site 4
S13
S
K
T
G
P
S
R
S
S
Y
Q
R
M
G
R
Site 5
S14
K
T
G
P
S
R
S
S
Y
Q
R
M
G
R
K
Site 6
Y15
T
G
P
S
R
S
S
Y
Q
R
M
G
R
K
S
Site 7
S22
Y
Q
R
M
G
R
K
S
Q
P
W
G
A
A
E
Site 8
T33
G
A
A
E
I
Q
C
T
R
C
G
R
R
V
S
Site 9
S40
T
R
C
G
R
R
V
S
R
S
S
G
H
H
C
Site 10
S42
C
G
R
R
V
S
R
S
S
G
H
H
C
E
L
Site 11
S43
G
R
R
V
S
R
S
S
G
H
H
C
E
L
Q
Site 12
Y86
A
V
N
T
R
Q
R
Y
Y
P
M
A
G
Y
I
Site 13
Y87
V
N
T
R
Q
R
Y
Y
P
M
A
G
Y
I
K
Site 14
S97
A
G
Y
I
K
E
D
S
I
M
E
K
L
Q
P
Site 15
T106
M
E
K
L
Q
P
K
T
I
K
N
C
S
Q
D
Site 16
S111
P
K
T
I
K
N
C
S
Q
D
F
K
K
T
A
Site 17
S130
T
G
L
E
R
S
A
S
T
D
K
T
L
L
N
Site 18
T134
R
S
A
S
T
D
K
T
L
L
N
S
S
A
V
Site 19
S138
T
D
K
T
L
L
N
S
S
A
V
M
L
D
T
Site 20
T145
S
S
A
V
M
L
D
T
N
T
A
E
E
I
D
Site 21
T157
E
I
D
E
A
L
N
T
A
H
H
S
F
E
Q
Site 22
S161
A
L
N
T
A
H
H
S
F
E
Q
L
S
I
A
Site 23
S166
H
H
S
F
E
Q
L
S
I
A
G
K
A
L
E
Site 24
S203
Q
L
L
A
F
F
D
S
R
K
K
N
L
C
E
Site 25
T215
L
C
E
E
F
A
R
T
T
D
D
Y
L
S
N
Site 26
T216
C
E
E
F
A
R
T
T
D
D
Y
L
S
N
L
Site 27
Y219
F
A
R
T
T
D
D
Y
L
S
N
L
I
K
A
Site 28
S221
R
T
T
D
D
Y
L
S
N
L
I
K
A
K
S
Site 29
S228
S
N
L
I
K
A
K
S
Y
I
E
E
K
K
N
Site 30
S252
R
A
L
Q
L
S
P
S
L
R
T
Y
C
D
L
Site 31
T269
I
I
R
T
L
Q
L
T
S
D
S
E
L
A
Q
Site 32
S272
T
L
Q
L
T
S
D
S
E
L
A
Q
V
S
S
Site 33
S279
S
E
L
A
Q
V
S
S
P
Q
L
R
N
P
P
Site 34
S289
L
R
N
P
P
R
L
S
V
N
C
S
E
I
I
Site 35
S310
G
K
I
E
F
R
D
S
T
K
C
Y
P
Q
E
Site 36
T311
K
I
E
F
R
D
S
T
K
C
Y
P
Q
E
N
Site 37
Y314
F
R
D
S
T
K
C
Y
P
Q
E
N
E
I
R
Site 38
Y328
R
Q
N
V
Q
K
K
Y
N
N
K
K
E
L
S
Site 39
Y337
N
K
K
E
L
S
C
Y
D
T
Y
P
P
L
E
Site 40
T339
K
E
L
S
C
Y
D
T
Y
P
P
L
E
K
K
Site 41
Y340
E
L
S
C
Y
D
T
Y
P
P
L
E
K
K
K
Site 42
S351
E
K
K
K
V
D
M
S
V
L
T
S
E
A
P
Site 43
T366
P
P
P
L
Q
P
E
T
N
D
V
H
L
E
A
Site 44
T384
Q
P
Q
K
D
V
A
T
A
S
P
K
T
I
A
Site 45
Y431
V
I
D
P
C
H
F
Y
I
R
K
Y
S
Q
I
Site 46
Y435
C
H
F
Y
I
R
K
Y
S
Q
I
K
D
A
K
Site 47
S456
N
E
F
C
N
R
S
S
H
L
D
P
S
D
I
Site 48
S461
R
S
S
H
L
D
P
S
D
I
L
E
L
G
A
Site 49
T496
I
P
I
E
G
R
N
T
R
K
P
C
S
P
T
Site 50
S501
R
N
T
R
K
P
C
S
P
T
R
L
F
V
H
Site 51
T534
I
V
T
G
V
V
D
T
H
V
R
P
E
H
S
Site 52
T562
L
R
K
S
E
P
Y
T
E
G
L
L
K
D
I
Site 53
S577
Q
P
L
A
Q
P
C
S
L
K
D
I
V
P
Q
Site 54
S586
K
D
I
V
P
Q
N
S
N
E
G
W
E
E
E
Site 55
S632
K
P
P
P
N
K
I
S
S
D
M
P
V
S
L
Site 56
S633
P
P
P
N
K
I
S
S
D
M
P
V
S
L
R
Site 57
S653
M
E
L
A
K
F
K
S
Q
S
L
R
S
H
F
Site 58
S655
L
A
K
F
K
S
Q
S
L
R
S
H
F
E
K
Site 59
Y668
E
K
N
T
T
L
H
Y
H
P
P
I
L
P
K
Site 60
S716
T
I
E
E
F
Y
K
S
E
D
G
E
N
L
E
Site 61
Y743
K
F
E
D
G
I
W
Y
R
A
K
V
I
G
L
Site 62
Y760
H
Q
E
V
E
V
K
Y
V
D
F
G
N
T
A
Site 63
Y795
A
I
K
C
K
L
A
Y
I
E
P
Y
K
R
T
Site 64
Y799
K
L
A
Y
I
E
P
Y
K
R
T
M
Q
W
S
Site 65
T851
G
A
P
E
M
T
T
T
S
I
N
D
Q
L
V
Site 66
S885
H
I
E
V
W
D
P
S
P
E
E
I
I
S
N
Site 67
S891
P
S
P
E
E
I
I
S
N
E
V
H
N
L
N
Site 68
S901
V
H
N
L
N
P
V
S
A
K
S
L
P
N
E
Site 69
S904
L
N
P
V
S
A
K
S
L
P
N
E
N
F
Q
Site 70
S912
L
P
N
E
N
F
Q
S
L
Y
N
K
E
L
P
Site 71
Y914
N
E
N
F
Q
S
L
Y
N
K
E
L
P
V
H
Site 72
S944
L
T
E
N
L
L
N
S
L
E
E
K
M
I
A
Site 73
Y953
E
E
K
M
I
A
A
Y
E
N
S
K
W
E
P
Site 74
T1020
K
L
E
E
N
L
K
T
M
G
R
L
S
L
E
Site 75
S1039
D
I
R
P
A
G
G
S
D
K
W
T
A
T
A
Site 76
T1043
A
G
G
S
D
K
W
T
A
T
A
C
D
C
L
Site 77
T1045
G
S
D
K
W
T
A
T
A
C
D
C
L
S
L
Site 78
S1067
T
I
I
L
Q
V
D
S
E
E
N
N
T
T
W
Site 79
T1072
V
D
S
E
E
N
N
T
T
W
P
L
P
V
K
Site 80
T1073
D
S
E
E
N
N
T
T
W
P
L
P
V
K
I
Site 81
S1093
K
G
E
R
V
D
V
S
K
Y
L
I
K
K
G
Site 82
Y1095
E
R
V
D
V
S
K
Y
L
I
K
K
G
L
A
Site 83
S1114
R
I
N
N
L
D
N
S
H
S
L
S
E
K
S
Site 84
S1116
N
N
L
D
N
S
H
S
L
S
E
K
S
L
E
Site 85
S1118
L
D
N
S
H
S
L
S
E
K
S
L
E
V
P
Site 86
S1121
S
H
S
L
S
E
K
S
L
E
V
P
L
E
Q
Site 87
S1131
V
P
L
E
Q
E
D
S
V
V
T
N
C
I
K
Site 88
T1147
N
F
D
P
D
K
K
T
A
D
I
I
S
E
Q
Site 89
S1152
K
K
T
A
D
I
I
S
E
Q
K
V
S
E
F
Site 90
S1157
I
I
S
E
Q
K
V
S
E
F
Q
E
K
I
L
Site 91
T1168
E
K
I
L
E
P
R
T
T
R
G
Y
K
P
P
Site 92
T1169
K
I
L
E
P
R
T
T
R
G
Y
K
P
P
A
Site 93
Y1172
E
P
R
T
T
R
G
Y
K
P
P
A
I
P
N
Site 94
S1216
K
M
T
N
E
I
Q
S
N
L
K
C
L
G
L
Site 95
Y1227
C
L
G
L
L
E
P
Y
F
W
K
K
G
E
A
Site 96
S1240
E
A
C
A
V
R
G
S
D
T
L
W
Y
R
G
Site 97
T1242
C
A
V
R
G
S
D
T
L
W
Y
R
G
K
V
Site 98
Y1245
R
G
S
D
T
L
W
Y
R
G
K
V
M
E
V
Site 99
Y1261
G
G
A
V
R
V
Q
Y
L
D
H
G
F
T
E
Site 100
S1316
E
V
L
Q
Q
L
L
S
K
R
Q
V
D
I
H
Site 101
Y1340
E
K
L
S
I
H
L
Y
F
D
G
M
S
L
S
Site 102
Y1348
F
D
G
M
S
L
S
Y
F
M
A
Y
Y
K
Y
Site 103
Y1352
S
L
S
Y
F
M
A
Y
Y
K
Y
C
T
S
E
Site 104
Y1353
L
S
Y
F
M
A
Y
Y
K
Y
C
T
S
E
H
Site 105
Y1355
Y
F
M
A
Y
Y
K
Y
C
T
S
E
H
T
E
Site 106
S1371
M
L
K
E
K
P
R
S
D
H
D
K
K
Y
E
Site 107
Y1377
R
S
D
H
D
K
K
Y
E
E
E
Q
W
E
I
Site 108
S1391
I
R
F
E
E
L
L
S
A
E
T
D
T
P
L
Site 109
T1394
E
E
L
L
S
A
E
T
D
T
P
L
L
P
P
Site 110
Y1402
D
T
P
L
L
P
P
Y
L
S
S
S
L
P
S
Site 111
S1404
P
L
L
P
P
Y
L
S
S
S
L
P
S
P
G
Site 112
S1405
L
L
P
P
Y
L
S
S
S
L
P
S
P
G
E
Site 113
S1406
L
P
P
Y
L
S
S
S
L
P
S
P
G
E
L
Site 114
S1433
E
V
Y
I
C
L
D
S
I
E
T
S
N
Q
S
Site 115
S1437
C
L
D
S
I
E
T
S
N
Q
S
N
Q
H
S
Site 116
S1440
S
I
E
T
S
N
Q
S
N
Q
H
S
D
T
D
Site 117
S1444
S
N
Q
S
N
Q
H
S
D
T
D
D
S
G
V
Site 118
T1446
Q
S
N
Q
H
S
D
T
D
D
S
G
V
S
G
Site 119
S1449
Q
H
S
D
T
D
D
S
G
V
S
G
E
S
E
Site 120
S1452
D
T
D
D
S
G
V
S
G
E
S
E
S
E
S
Site 121
S1455
D
S
G
V
S
G
E
S
E
S
E
S
L
D
E
Site 122
S1459
S
G
E
S
E
S
E
S
L
D
E
A
L
Q
R
Site 123
T1478
V
E
A
L
P
P
L
T
D
F
R
T
E
M
P
Site 124
T1482
P
P
L
T
D
F
R
T
E
M
P
C
L
A
E
Site 125
Y1490
E
M
P
C
L
A
E
Y
D
D
G
L
W
Y
R
Site 126
Y1496
E
Y
D
D
G
L
W
Y
R
A
K
I
V
A
I
Site 127
T1525
Y
G
S
T
A
K
L
T
L
N
R
L
C
Q
I
Site 128
Y1539
I
P
S
H
L
M
R
Y
P
A
R
A
I
K
V
Site 129
T1561
P
L
R
D
L
G
E
T
R
I
P
Y
C
P
K
Site 130
Y1565
L
G
E
T
R
I
P
Y
C
P
K
W
S
M
E
Site 131
S1590
G
K
Q
L
Y
A
V
S
M
A
P
A
P
E
Q
Site 132
T1600
P
A
P
E
Q
I
V
T
L
Y
D
D
E
Q
H
Site 133
Y1602
P
E
Q
I
V
T
L
Y
D
D
E
Q
H
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation