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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PACSIN1
Full Name:
Protein kinase C and casein kinase substrate in neurons protein 1
Alias:
KIAA1379; PACN1; Protein kinase C and casein kinase substrate in neurons 1; SDPI; Syndapin I
Type:
COPI-coated vesicle protein
Mass (Da):
50966
Number AA:
444
UniProt ID:
Q9BY11
International Prot ID:
IPI00011515
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004672
PhosphoSite+
KinaseNET
Biological Process:
GO:0006897
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
S
S
Y
D
E
A
S
L
A
P
E
E
T
T
Site 2
S18
A
P
E
E
T
T
D
S
F
W
E
V
G
N
Y
Site 3
Y25
S
F
W
E
V
G
N
Y
K
R
T
V
K
R
I
Site 4
T28
E
V
G
N
Y
K
R
T
V
K
R
I
D
D
G
Site 5
Y77
L
I
E
K
G
P
Q
Y
G
S
L
E
R
A
W
Site 6
S79
E
K
G
P
Q
Y
G
S
L
E
R
A
W
G
A
Site 7
Y121
K
N
W
Q
K
D
A
Y
H
K
Q
I
M
G
G
Site 8
T179
T
R
E
M
N
S
K
T
E
Q
S
V
T
P
E
Site 9
S182
M
N
S
K
T
E
Q
S
V
T
P
E
Q
Q
K
Site 10
T184
S
K
T
E
Q
S
V
T
P
E
Q
Q
K
K
L
Site 11
Y209
V
Q
K
T
Q
E
K
Y
E
K
V
L
E
D
V
Site 12
T220
L
E
D
V
G
K
T
T
P
Q
Y
M
E
N
M
Site 13
Y223
V
G
K
T
T
P
Q
Y
M
E
N
M
E
Q
V
Site 14
S262
H
L
N
L
A
E
N
S
S
Y
I
H
V
Y
R
Site 15
S263
L
N
L
A
E
N
S
S
Y
I
H
V
Y
R
E
Site 16
Y264
N
L
A
E
N
S
S
Y
I
H
V
Y
R
E
L
Site 17
S289
E
D
L
R
W
F
R
S
T
S
G
P
G
M
P
Site 18
T290
D
L
R
W
F
R
S
T
S
G
P
G
M
P
M
Site 19
S291
L
R
W
F
R
S
T
S
G
P
G
M
P
M
N
Site 20
S339
T
G
A
V
E
S
T
S
Q
A
G
D
R
G
S
Site 21
S346
S
Q
A
G
D
R
G
S
V
S
S
Y
D
R
G
Site 22
S348
A
G
D
R
G
S
V
S
S
Y
D
R
G
Q
P
Site 23
S349
G
D
R
G
S
V
S
S
Y
D
R
G
Q
P
Y
Site 24
Y350
D
R
G
S
V
S
S
Y
D
R
G
Q
P
Y
A
Site 25
Y356
S
Y
D
R
G
Q
P
Y
A
T
E
W
S
D
D
Site 26
S361
Q
P
Y
A
T
E
W
S
D
D
E
S
G
N
P
Site 27
S365
T
E
W
S
D
D
E
S
G
N
P
F
G
G
S
Site 28
S372
S
G
N
P
F
G
G
S
E
T
N
G
G
A
N
Site 29
S385
A
N
P
F
E
D
D
S
K
G
V
R
V
R
A
Site 30
Y394
G
V
R
V
R
A
L
Y
D
Y
D
G
Q
E
Q
Site 31
Y396
R
V
R
A
L
Y
D
Y
D
G
Q
E
Q
D
E
Site 32
S405
G
Q
E
Q
D
E
L
S
F
K
A
G
D
E
L
Site 33
S430
W
C
R
G
R
L
D
S
G
Q
L
G
L
Y
P
Site 34
Y436
D
S
G
Q
L
G
L
Y
P
A
N
Y
V
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation