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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
YTHDF1
Full Name:
YTH domain family protein 1
Alias:
C20orf21; DACA-1; Dermatomyositis associated with cancer autoantigen 1; Dermatomyositis associated with cancer putative autoantigen 1; FLJ20391; YTH domain family, member 1; YTHD1
Type:
Uncharacterized protein
Mass (Da):
60874
Number AA:
559
UniProt ID:
Q9BYJ9
International Prot ID:
IPI00221345
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
S
A
T
S
V
D
T
Q
R
T
K
G
Q
D
Site 2
S22
D
N
K
V
Q
N
G
S
L
H
Q
K
D
T
V
Site 3
T28
G
S
L
H
Q
K
D
T
V
H
D
N
D
F
E
Site 4
Y37
H
D
N
D
F
E
P
Y
L
T
G
Q
S
N
Q
Site 5
T39
N
D
F
E
P
Y
L
T
G
Q
S
N
Q
S
N
Site 6
S45
L
T
G
Q
S
N
Q
S
N
S
Y
P
S
M
S
Site 7
S47
G
Q
S
N
Q
S
N
S
Y
P
S
M
S
D
P
Site 8
Y48
Q
S
N
Q
S
N
S
Y
P
S
M
S
D
P
Y
Site 9
S50
N
Q
S
N
S
Y
P
S
M
S
D
P
Y
L
S
Site 10
S52
S
N
S
Y
P
S
M
S
D
P
Y
L
S
S
Y
Site 11
Y55
Y
P
S
M
S
D
P
Y
L
S
S
Y
Y
P
P
Site 12
S57
S
M
S
D
P
Y
L
S
S
Y
Y
P
P
S
I
Site 13
S58
M
S
D
P
Y
L
S
S
Y
Y
P
P
S
I
G
Site 14
Y59
S
D
P
Y
L
S
S
Y
Y
P
P
S
I
G
F
Site 15
Y60
D
P
Y
L
S
S
Y
Y
P
P
S
I
G
F
P
Site 16
S63
L
S
S
Y
Y
P
P
S
I
G
F
P
Y
S
L
Site 17
S69
P
S
I
G
F
P
Y
S
L
N
E
A
P
W
S
Site 18
S76
S
L
N
E
A
P
W
S
T
A
G
D
P
P
I
Site 19
Y85
A
G
D
P
P
I
P
Y
L
T
T
Y
G
Q
L
Site 20
T87
D
P
P
I
P
Y
L
T
T
Y
G
Q
L
S
N
Site 21
Y89
P
I
P
Y
L
T
T
Y
G
Q
L
S
N
G
D
Site 22
Y116
G
G
L
G
N
N
I
Y
Q
H
R
F
N
F
F
Site 23
S130
F
P
E
N
P
A
F
S
A
W
G
T
S
G
S
Site 24
T134
P
A
F
S
A
W
G
T
S
G
S
Q
G
Q
Q
Site 25
S137
S
A
W
G
T
S
G
S
Q
G
Q
Q
T
Q
S
Site 26
T142
S
G
S
Q
G
Q
Q
T
Q
S
S
A
Y
G
S
Site 27
S144
S
Q
G
Q
Q
T
Q
S
S
A
Y
G
S
S
Y
Site 28
S145
Q
G
Q
Q
T
Q
S
S
A
Y
G
S
S
Y
T
Site 29
S149
T
Q
S
S
A
Y
G
S
S
Y
T
Y
P
P
S
Site 30
S150
Q
S
S
A
Y
G
S
S
Y
T
Y
P
P
S
S
Site 31
Y151
S
S
A
Y
G
S
S
Y
T
Y
P
P
S
S
L
Site 32
T152
S
A
Y
G
S
S
Y
T
Y
P
P
S
S
L
G
Site 33
Y153
A
Y
G
S
S
Y
T
Y
P
P
S
S
L
G
G
Site 34
S156
S
S
Y
T
Y
P
P
S
S
L
G
G
T
V
V
Site 35
S157
S
Y
T
Y
P
P
S
S
L
G
G
T
V
V
D
Site 36
T161
P
P
S
S
L
G
G
T
V
V
D
G
Q
P
G
Site 37
S171
D
G
Q
P
G
F
H
S
D
T
L
S
K
A
P
Site 38
T173
Q
P
G
F
H
S
D
T
L
S
K
A
P
G
M
Site 39
S175
G
F
H
S
D
T
L
S
K
A
P
G
M
N
S
Site 40
S182
S
K
A
P
G
M
N
S
L
E
Q
G
M
V
G
Site 41
S198
K
I
G
D
V
S
S
S
A
V
K
T
V
G
S
Site 42
S229
T
N
V
N
M
P
V
S
K
P
T
S
W
A
A
Site 43
S233
M
P
V
S
K
P
T
S
W
A
A
I
A
S
K
Site 44
S239
T
S
W
A
A
I
A
S
K
P
A
K
P
Q
P
Site 45
T250
K
P
Q
P
K
M
K
T
K
S
G
P
V
M
G
Site 46
S252
Q
P
K
M
K
T
K
S
G
P
V
M
G
G
G
Site 47
T273
K
H
N
M
D
I
G
T
W
D
N
K
G
P
V
Site 48
S291
P
V
P
Q
Q
A
P
S
P
Q
A
A
P
Q
P
Site 49
Y317
P
A
L
A
Q
P
Q
Y
Q
S
P
Q
Q
P
P
Site 50
S319
L
A
Q
P
Q
Y
Q
S
P
Q
Q
P
P
Q
T
Site 51
T326
S
P
Q
Q
P
P
Q
T
R
W
V
A
P
R
N
Site 52
S346
G
Q
S
G
G
A
G
S
D
S
N
S
P
G
N
Site 53
S348
S
G
G
A
G
S
D
S
N
S
P
G
N
V
Q
Site 54
S350
G
A
G
S
D
S
N
S
P
G
N
V
Q
P
N
Site 55
S358
P
G
N
V
Q
P
N
S
A
P
S
V
E
S
H
Site 56
S361
V
Q
P
N
S
A
P
S
V
E
S
H
P
V
L
Site 57
S376
E
K
L
K
A
A
H
S
Y
N
P
K
E
F
E
Site 58
S396
G
R
V
F
I
I
K
S
Y
S
E
D
D
I
H
Site 59
S398
V
F
I
I
K
S
Y
S
E
D
D
I
H
R
S
Site 60
Y408
D
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
Site 61
S409
I
H
R
S
I
K
Y
S
I
W
C
S
T
E
H
Site 62
S413
I
K
Y
S
I
W
C
S
T
E
H
G
N
K
R
Site 63
S423
H
G
N
K
R
L
D
S
A
F
R
C
M
S
S
Site 64
S429
D
S
A
F
R
C
M
S
S
K
G
P
V
Y
L
Site 65
S454
C
G
V
A
E
M
K
S
P
V
D
Y
G
T
S
Site 66
Y458
E
M
K
S
P
V
D
Y
G
T
S
A
G
V
W
Site 67
T460
K
S
P
V
D
Y
G
T
S
A
G
V
W
S
Q
Site 68
S466
G
T
S
A
G
V
W
S
Q
D
K
W
K
G
K
Site 69
T503
N
N
D
N
K
P
V
T
N
S
R
D
T
Q
E
Site 70
T508
P
V
T
N
S
R
D
T
Q
E
V
P
L
E
K
Site 71
S525
Q
V
L
K
I
I
S
S
Y
K
H
T
T
S
I
Site 72
T529
I
I
S
S
Y
K
H
T
T
S
I
F
D
D
F
Site 73
S531
S
S
Y
K
H
T
T
S
I
F
D
D
F
A
H
Site 74
Y539
I
F
D
D
F
A
H
Y
E
K
R
Q
E
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation