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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PBX4
Full Name:
Pre-B-cell leukemia transcription factor 4
Alias:
Homeobox protein PBX4
Type:
Mass (Da):
40854
Number AA:
374
UniProt ID:
Q9BYU1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
P
P
R
P
A
P
S
P
P
A
P
R
R
L
Site 2
T19
P
A
P
R
R
L
D
T
S
D
V
L
Q
Q
I
Site 3
S20
A
P
R
R
L
D
T
S
D
V
L
Q
Q
I
M
Site 4
S33
I
M
A
I
T
D
Q
S
L
D
E
A
Q
A
R
Site 5
S67
I
K
E
K
T
V
V
S
I
R
G
I
Q
D
E
Site 6
T112
V
A
R
A
G
T
A
T
P
G
G
C
P
N
D
Site 7
S121
G
G
C
P
N
D
N
S
I
E
H
S
D
Y
R
Site 8
S125
N
D
N
S
I
E
H
S
D
Y
R
A
K
L
S
Site 9
Y127
N
S
I
E
H
S
D
Y
R
A
K
L
S
Q
I
Site 10
S132
S
D
Y
R
A
K
L
S
Q
I
R
Q
I
Y
H
Site 11
Y138
L
S
Q
I
R
Q
I
Y
H
S
E
L
E
K
Y
Site 12
S140
Q
I
R
Q
I
Y
H
S
E
L
E
K
Y
E
Q
Site 13
Y145
Y
H
S
E
L
E
K
Y
E
Q
A
C
R
E
F
Site 14
T153
E
Q
A
C
R
E
F
T
T
H
V
T
N
L
L
Site 15
S164
T
N
L
L
Q
E
Q
S
R
M
R
P
V
S
P
Site 16
S170
Q
S
R
M
R
P
V
S
P
K
E
I
E
R
M
Site 17
S218
R
R
K
R
R
N
F
S
K
Q
A
T
E
V
L
Site 18
T222
R
N
F
S
K
Q
A
T
E
V
L
N
E
Y
F
Site 19
Y228
A
T
E
V
L
N
E
Y
F
Y
S
H
L
N
N
Site 20
Y230
E
V
L
N
E
Y
F
Y
S
H
L
N
N
P
Y
Site 21
Y237
Y
S
H
L
N
N
P
Y
P
S
E
E
A
K
E
Site 22
T253
L
A
R
K
G
G
L
T
I
S
Q
V
S
N
W
Site 23
S255
R
K
G
G
L
T
I
S
Q
V
S
N
W
F
G
Site 24
S258
G
L
T
I
S
Q
V
S
N
W
F
G
N
K
R
Site 25
Y268
F
G
N
K
R
I
R
Y
K
K
N
M
G
K
F
Site 26
Y282
F
Q
E
E
A
T
I
Y
T
G
K
T
A
V
D
Site 27
T290
T
G
K
T
A
V
D
T
T
E
V
G
V
P
G
Site 28
T291
G
K
T
A
V
D
T
T
E
V
G
V
P
G
N
Site 29
S301
G
V
P
G
N
H
A
S
C
L
S
T
P
S
S
Site 30
S304
G
N
H
A
S
C
L
S
T
P
S
S
G
S
S
Site 31
T305
N
H
A
S
C
L
S
T
P
S
S
G
S
S
G
Site 32
S307
A
S
C
L
S
T
P
S
S
G
S
S
G
P
F
Site 33
S308
S
C
L
S
T
P
S
S
G
S
S
G
P
F
P
Site 34
S310
L
S
T
P
S
S
G
S
S
G
P
F
P
L
P
Site 35
S311
S
T
P
S
S
G
S
S
G
P
F
P
L
P
S
Site 36
S331
L
T
L
R
T
L
A
S
L
Q
P
P
P
G
G
Site 37
S343
P
G
G
G
C
L
Q
S
Q
A
Q
G
S
W
Q
Site 38
S348
L
Q
S
Q
A
Q
G
S
W
Q
G
A
T
P
Q
Site 39
T353
Q
G
S
W
Q
G
A
T
P
Q
P
A
T
A
S
Site 40
T358
G
A
T
P
Q
P
A
T
A
S
P
A
G
D
P
Site 41
S360
T
P
Q
P
A
T
A
S
P
A
G
D
P
G
S
Site 42
S367
S
P
A
G
D
P
G
S
I
N
S
S
T
S
N
Site 43
S370
G
D
P
G
S
I
N
S
S
T
S
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation