PhosphoNET

           
Protein Info 
   
Short Name:  PBX4
Full Name:  Pre-B-cell leukemia transcription factor 4
Alias:  Homeobox protein PBX4
Type: 
Mass (Da):  40854
Number AA:  374
UniProt ID:  Q9BYU1
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10APPRPAPSPPAPRRL
Site 2T19PAPRRLDTSDVLQQI
Site 3S20APRRLDTSDVLQQIM
Site 4S33IMAITDQSLDEAQAR
Site 5S67IKEKTVVSIRGIQDE
Site 6T112VARAGTATPGGCPND
Site 7S121GGCPNDNSIEHSDYR
Site 8S125NDNSIEHSDYRAKLS
Site 9Y127NSIEHSDYRAKLSQI
Site 10S132SDYRAKLSQIRQIYH
Site 11Y138LSQIRQIYHSELEKY
Site 12S140QIRQIYHSELEKYEQ
Site 13Y145YHSELEKYEQACREF
Site 14T153EQACREFTTHVTNLL
Site 15S164TNLLQEQSRMRPVSP
Site 16S170QSRMRPVSPKEIERM
Site 17S218RRKRRNFSKQATEVL
Site 18T222RNFSKQATEVLNEYF
Site 19Y228ATEVLNEYFYSHLNN
Site 20Y230EVLNEYFYSHLNNPY
Site 21Y237YSHLNNPYPSEEAKE
Site 22T253LARKGGLTISQVSNW
Site 23S255RKGGLTISQVSNWFG
Site 24S258GLTISQVSNWFGNKR
Site 25Y268FGNKRIRYKKNMGKF
Site 26Y282FQEEATIYTGKTAVD
Site 27T290TGKTAVDTTEVGVPG
Site 28T291GKTAVDTTEVGVPGN
Site 29S301GVPGNHASCLSTPSS
Site 30S304GNHASCLSTPSSGSS
Site 31T305NHASCLSTPSSGSSG
Site 32S307ASCLSTPSSGSSGPF
Site 33S308SCLSTPSSGSSGPFP
Site 34S310LSTPSSGSSGPFPLP
Site 35S311STPSSGSSGPFPLPS
Site 36S331LTLRTLASLQPPPGG
Site 37S343PGGGCLQSQAQGSWQ
Site 38S348LQSQAQGSWQGATPQ
Site 39T353QGSWQGATPQPATAS
Site 40T358GATPQPATASPAGDP
Site 41S360TPQPATASPAGDPGS
Site 42S367SPAGDPGSINSSTSN
Site 43S370GDPGSINSSTSN___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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