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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FRMD8
Full Name:
FERM domain-containing protein 8
Alias:
FLJ32216
Type:
Uncharacterized protein
Mass (Da):
51218
Number AA:
464
UniProt ID:
Q9BZ67
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
Q
P
G
P
A
E
R
S
H
R
S
S
V
S
S
Site 2
S20
P
A
E
R
S
H
R
S
S
V
S
S
V
G
A
Site 3
S21
A
E
R
S
H
R
S
S
V
S
S
V
G
A
R
Site 4
S24
S
H
R
S
S
V
S
S
V
G
A
R
A
A
D
Site 5
S53
V
E
N
L
P
S
L
S
A
H
E
L
H
R
A
Site 6
T109
P
E
L
L
L
R
F
T
S
A
P
D
D
D
V
Site 7
S110
E
L
L
L
R
F
T
S
A
P
D
D
D
V
A
Site 8
Y149
E
E
V
L
R
L
L
Y
E
E
A
K
G
N
V
Site 9
Y161
G
N
V
L
A
A
R
Y
P
C
D
V
E
D
C
Site 10
Y183
C
R
V
Q
L
G
P
Y
Q
P
G
R
P
A
A
Site 11
S199
D
L
R
E
K
L
D
S
F
L
P
A
H
L
C
Site 12
S211
H
L
C
K
R
G
Q
S
L
F
A
A
L
R
G
Site 13
S242
R
Q
V
Q
E
V
S
S
D
G
G
C
E
A
A
Site 14
Y257
L
G
T
H
Y
R
A
Y
L
L
K
C
H
E
L
Site 15
S293
R
G
G
R
K
P
V
S
V
A
I
S
L
E
G
Site 16
S306
E
G
V
H
V
I
D
S
R
E
K
H
V
L
L
Site 17
S321
G
L
R
F
Q
E
L
S
W
D
H
T
S
P
E
Site 18
T325
Q
E
L
S
W
D
H
T
S
P
E
E
E
E
P
Site 19
S326
E
L
S
W
D
H
T
S
P
E
E
E
E
P
I
Site 20
S342
W
L
E
F
D
G
D
S
E
G
T
P
V
N
K
Site 21
T345
F
D
G
D
S
E
G
T
P
V
N
K
L
L
K
Site 22
S355
N
K
L
L
K
I
Y
S
K
Q
A
E
L
M
S
Site 23
S363
K
Q
A
E
L
M
S
S
L
I
E
Y
C
I
E
Site 24
S383
E
P
A
G
P
Q
D
S
A
T
G
S
P
S
D
Site 25
T385
A
G
P
Q
D
S
A
T
G
S
P
S
D
P
S
Site 26
S387
P
Q
D
S
A
T
G
S
P
S
D
P
S
S
S
Site 27
S389
D
S
A
T
G
S
P
S
D
P
S
S
S
L
A
Site 28
S392
T
G
S
P
S
D
P
S
S
S
L
A
P
V
Q
Site 29
S393
G
S
P
S
D
P
S
S
S
L
A
P
V
Q
R
Site 30
S394
S
P
S
D
P
S
S
S
L
A
P
V
Q
R
P
Site 31
S408
P
K
L
R
R
Q
G
S
V
V
S
S
R
I
Q
Site 32
S411
R
R
Q
G
S
V
V
S
S
R
I
Q
H
L
S
Site 33
S412
R
Q
G
S
V
V
S
S
R
I
Q
H
L
S
T
Site 34
S418
S
S
R
I
Q
H
L
S
T
I
D
Y
V
E
D
Site 35
T419
S
R
I
Q
H
L
S
T
I
D
Y
V
E
D
G
Site 36
Y422
Q
H
L
S
T
I
D
Y
V
E
D
G
K
G
I
Site 37
T437
R
R
V
K
P
K
R
T
T
S
F
F
S
R
Q
Site 38
T438
R
V
K
P
K
R
T
T
S
F
F
S
R
Q
L
Site 39
S439
V
K
P
K
R
T
T
S
F
F
S
R
Q
L
S
Site 40
S442
K
R
T
T
S
F
F
S
R
Q
L
S
L
G
Q
Site 41
S446
S
F
F
S
R
Q
L
S
L
G
Q
G
S
Y
T
Site 42
S451
Q
L
S
L
G
Q
G
S
Y
T
V
V
Q
P
G
Site 43
Y452
L
S
L
G
Q
G
S
Y
T
V
V
Q
P
G
D
Site 44
T453
S
L
G
Q
G
S
Y
T
V
V
Q
P
G
D
S
Site 45
S460
T
V
V
Q
P
G
D
S
L
E
Q
G
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation