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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Nuf2
Full Name:
Kinetochore protein Nuf2
Alias:
Cancer/testis antigen 106; CDCA1; Cell division cycle-associated protein 1; CT106; NUF2, NDC80 kinetochore complex component,; Nuf2R
Type:
DNA replication protein
Mass (Da):
54304
Number AA:
464
UniProt ID:
Q9BZD4
International Prot ID:
IPI00305887
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031262
GO:0000777
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007059
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
H
I
R
N
K
I
L
T
G
A
D
G
K
N
L
Site 2
Y37
N
L
T
K
N
D
L
Y
P
N
P
K
P
E
V
Site 3
Y65
G
I
R
L
E
H
F
Y
M
M
P
V
N
S
E
Site 4
Y75
P
V
N
S
E
V
M
Y
P
H
L
M
E
G
F
Site 5
T117
L
C
P
K
A
K
R
T
S
R
F
L
S
G
I
Site 6
S118
C
P
K
A
K
R
T
S
R
F
L
S
G
I
I
Site 7
S122
K
R
T
S
R
F
L
S
G
I
I
N
F
I
H
Site 8
Y138
R
E
A
C
R
E
T
Y
M
E
F
L
W
Q
Y
Site 9
Y145
Y
M
E
F
L
W
Q
Y
K
S
S
A
D
K
M
Site 10
S171
M
K
L
E
R
L
D
S
V
P
V
E
E
Q
E
Site 11
S184
Q
E
E
F
K
Q
L
S
D
G
I
Q
E
L
Q
Site 12
S193
G
I
Q
E
L
Q
Q
S
L
N
Q
D
F
H
Q
Site 13
S210
I
V
L
Q
E
G
N
S
Q
K
K
S
N
I
S
Site 14
S214
E
G
N
S
Q
K
K
S
N
I
S
E
K
T
K
Site 15
T220
K
S
N
I
S
E
K
T
K
R
L
N
E
L
K
Site 16
S239
S
L
K
E
I
Q
E
S
L
K
T
K
I
V
D
Site 17
T242
E
I
Q
E
S
L
K
T
K
I
V
D
S
P
E
Site 18
S247
L
K
T
K
I
V
D
S
P
E
K
L
K
N
Y
Site 19
T261
Y
K
E
K
M
K
D
T
V
Q
K
L
K
N
A
Site 20
Y276
R
Q
E
V
V
E
K
Y
E
I
Y
G
D
S
V
Site 21
S282
K
Y
E
I
Y
G
D
S
V
D
C
L
P
S
C
Site 22
Y296
C
Q
L
E
V
Q
L
Y
Q
K
K
I
Q
D
L
Site 23
S304
Q
K
K
I
Q
D
L
S
D
N
R
E
K
L
A
Site 24
S312
D
N
R
E
K
L
A
S
I
L
K
E
S
L
N
Site 25
S326
N
L
E
D
Q
I
E
S
D
E
S
E
L
K
K
Site 26
S329
D
Q
I
E
S
D
E
S
E
L
K
K
L
K
T
Site 27
T336
S
E
L
K
K
L
K
T
E
E
N
S
F
K
R
Site 28
S340
K
L
K
T
E
E
N
S
F
K
R
L
M
I
V
Site 29
T354
V
K
K
E
K
L
A
T
A
Q
F
K
I
N
K
Site 30
Y369
K
H
E
D
V
K
Q
Y
K
R
T
V
I
E
D
Site 31
Y388
Q
E
K
R
G
A
V
Y
E
R
V
T
T
I
N
Site 32
T392
G
A
V
Y
E
R
V
T
T
I
N
Q
E
I
Q
Site 33
T393
A
V
Y
E
R
V
T
T
I
N
Q
E
I
Q
K
Site 34
S419
A
E
R
E
K
L
K
S
Q
E
I
F
L
N
L
Site 35
T428
E
I
F
L
N
L
K
T
A
L
E
K
Y
H
D
Site 36
Y433
L
K
T
A
L
E
K
Y
H
D
G
I
E
K
A
Site 37
Y445
E
K
A
A
E
D
S
Y
A
K
I
D
E
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation