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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLIS2
Full Name:
Zinc finger protein GLIS2
Alias:
GLIS family zinc finger 2; GLI-similar 2; Kruppel-like zinc finger GLIS2; Nephrocystin-7; Neuronal Krueppel-like; NKL; NPHP7
Type:
Transcription protein
Mass (Da):
55705
Number AA:
524
UniProt ID:
Q9BZE0
International Prot ID:
IPI00000274
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0016563
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0016481
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
E
P
L
D
L
K
L
S
I
T
K
L
R
A
A
Site 2
T27
A
R
E
K
R
E
R
T
L
G
V
V
R
P
R
Site 3
S46
E
L
G
L
V
D
D
S
P
T
L
G
S
P
G
Site 4
T48
G
L
V
D
D
S
P
T
L
G
S
P
G
S
P
Site 5
S51
D
D
S
P
T
L
G
S
P
G
S
P
P
S
G
Site 6
S57
G
S
P
G
S
P
P
S
G
F
L
L
N
S
K
Site 7
S63
P
S
G
F
L
L
N
S
K
F
P
E
K
V
E
Site 8
S74
E
K
V
E
G
R
F
S
A
A
P
L
V
D
L
Site 9
S87
D
L
S
L
S
P
P
S
G
L
D
S
P
N
G
Site 10
S91
S
P
P
S
G
L
D
S
P
N
G
S
S
S
L
Site 11
S95
G
L
D
S
P
N
G
S
S
S
L
S
P
E
R
Site 12
S97
D
S
P
N
G
S
S
S
L
S
P
E
R
Q
G
Site 13
S99
P
N
G
S
S
S
L
S
P
E
R
Q
G
N
G
Site 14
S113
G
D
L
P
P
V
P
S
A
S
D
F
Q
P
L
Site 15
S115
L
P
P
V
P
S
A
S
D
F
Q
P
L
R
Y
Site 16
Y122
S
D
F
Q
P
L
R
Y
L
D
G
V
P
S
S
Site 17
S148
A
L
H
L
P
A
S
S
F
L
T
P
P
K
D
Site 18
T151
L
P
A
S
S
F
L
T
P
P
K
D
K
C
L
Site 19
S159
P
P
K
D
K
C
L
S
P
D
L
P
L
P
K
Site 20
Y192
L
V
D
H
V
N
D
Y
H
V
K
P
E
K
D
Site 21
Y220
G
R
G
F
N
A
R
Y
K
M
L
I
H
I
R
Site 22
T230
L
I
H
I
R
T
H
T
N
E
K
P
H
R
C
Site 23
T239
E
K
P
H
R
C
P
T
C
S
K
S
F
S
R
Site 24
S241
P
H
R
C
P
T
C
S
K
S
F
S
R
L
E
Site 25
S243
R
C
P
T
C
S
K
S
F
S
R
L
E
N
L
Site 26
S245
P
T
C
S
K
S
F
S
R
L
E
N
L
K
I
Site 27
T258
K
I
H
N
R
S
H
T
G
E
K
P
Y
V
C
Site 28
Y263
S
H
T
G
E
K
P
Y
V
C
P
Y
E
G
C
Site 29
Y267
E
K
P
Y
V
C
P
Y
E
G
C
N
K
R
Y
Site 30
S275
E
G
C
N
K
R
Y
S
N
S
S
D
R
F
K
Site 31
S277
C
N
K
R
Y
S
N
S
S
D
R
F
K
H
T
Site 32
S278
N
K
R
Y
S
N
S
S
D
R
F
K
H
T
R
Site 33
Y288
F
K
H
T
R
T
H
Y
V
D
K
P
Y
Y
C
Site 34
Y293
T
H
Y
V
D
K
P
Y
Y
C
K
M
P
G
C
Site 35
Y304
M
P
G
C
H
K
R
Y
T
D
P
S
S
L
R
Site 36
T305
P
G
C
H
K
R
Y
T
D
P
S
S
L
R
K
Site 37
S308
H
K
R
Y
T
D
P
S
S
L
R
K
H
I
K
Site 38
S309
K
R
Y
T
D
P
S
S
L
R
K
H
I
K
A
Site 39
S322
K
A
H
G
H
F
V
S
H
E
Q
Q
E
L
L
Site 40
S392
A
C
G
N
G
G
G
S
G
G
G
G
G
M
G
Site 41
S450
E
G
E
K
G
R
G
S
V
P
T
R
A
L
G
Site 42
T453
K
G
R
G
S
V
P
T
R
A
L
G
M
E
G
Site 43
T463
L
G
M
E
G
H
K
T
P
L
E
R
T
E
S
Site 44
S470
T
P
L
E
R
T
E
S
S
C
S
R
P
S
P
Site 45
S471
P
L
E
R
T
E
S
S
C
S
R
P
S
P
D
Site 46
S473
E
R
T
E
S
S
C
S
R
P
S
P
D
G
L
Site 47
S476
E
S
S
C
S
R
P
S
P
D
G
L
P
L
L
Site 48
S496
D
L
S
T
G
V
N
S
A
A
S
S
P
E
A
Site 49
S500
G
V
N
S
A
A
S
S
P
E
A
L
A
P
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation