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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GTPBP1
Full Name:
Nucleolar GTP-binding protein 1
Alias:
GP1; GP-1; G-protein 1; GTB1; GTP binding protein 1; GTPB1; GTPB1_HUMAN; HSPC018
Type:
G protein
Mass (Da):
72454
Number AA:
634
UniProt ID:
Q9BZE4
International Prot ID:
IPI00010463
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0048471
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
GO:0007165
GO:0008285
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
H
Y
N
F
K
K
I
T
V
V
P
S
A
K
D
Site 2
T22
A
K
D
F
I
D
L
T
L
S
K
T
Q
R
K
Site 3
S24
D
F
I
D
L
T
L
S
K
T
Q
R
K
T
P
Site 4
T26
I
D
L
T
L
S
K
T
Q
R
K
T
P
T
V
Site 5
T30
L
S
K
T
Q
R
K
T
P
T
V
I
H
K
H
Site 6
T32
K
T
Q
R
K
T
P
T
V
I
H
K
H
Y
Q
Site 7
Y38
P
T
V
I
H
K
H
Y
Q
I
H
R
I
R
H
Site 8
Y47
I
H
R
I
R
H
F
Y
M
R
K
V
K
F
T
Site 9
Y58
V
K
F
T
Q
Q
N
Y
H
D
R
L
S
Q
I
Site 10
S63
Q
N
Y
H
D
R
L
S
Q
I
L
T
D
F
P
Site 11
T67
D
R
L
S
Q
I
L
T
D
F
P
K
L
D
D
Site 12
Y87
A
D
L
M
N
I
L
Y
D
K
D
H
Y
K
L
Site 13
Y92
I
L
Y
D
K
D
H
Y
K
L
A
L
G
Q
I
Site 14
Y113
V
D
N
V
A
K
D
Y
V
R
L
M
K
Y
G
Site 15
Y119
D
Y
V
R
L
M
K
Y
G
D
S
L
Y
R
C
Site 16
S122
R
L
M
K
Y
G
D
S
L
Y
R
C
K
Q
L
Site 17
Y124
M
K
Y
G
D
S
L
Y
R
C
K
Q
L
K
R
Site 18
T139
A
A
L
G
R
M
C
T
V
I
K
R
Q
K
Q
Site 19
S147
V
I
K
R
Q
K
Q
S
L
E
Y
L
E
Q
V
Site 20
S159
E
Q
V
R
Q
H
L
S
R
L
P
T
I
D
P
Site 21
T163
Q
H
L
S
R
L
P
T
I
D
P
N
T
R
T
Site 22
T170
T
I
D
P
N
T
R
T
L
L
L
C
G
Y
P
Site 23
Y176
R
T
L
L
L
C
G
Y
P
N
V
G
K
S
S
Site 24
S182
G
Y
P
N
V
G
K
S
S
F
I
N
K
V
T
Site 25
S183
Y
P
N
V
G
K
S
S
F
I
N
K
V
T
R
Site 26
Y212
L
F
V
G
H
M
D
Y
K
Y
L
R
W
Q
V
Site 27
Y214
V
G
H
M
D
Y
K
Y
L
R
W
Q
V
V
D
Site 28
T222
L
R
W
Q
V
V
D
T
P
G
I
L
D
H
P
Site 29
T235
H
P
L
E
D
R
N
T
I
E
M
Q
A
I
T
Site 30
S300
V
K
R
I
A
E
L
S
E
D
D
Q
K
I
F
Site 31
T308
E
D
D
Q
K
I
F
T
D
L
Q
S
E
G
F
Site 32
S312
K
I
F
T
D
L
Q
S
E
G
F
P
V
I
E
Site 33
T346
L
L
A
H
R
V
E
T
K
M
K
G
N
K
V
Site 34
T390
A
R
R
K
R
M
E
T
E
E
S
R
K
K
R
Site 35
S393
K
R
M
E
T
E
E
S
R
K
K
R
E
R
D
Site 36
Y409
E
L
E
M
G
D
D
Y
I
L
D
L
Q
K
Y
Site 37
Y416
Y
I
L
D
L
Q
K
Y
W
D
L
M
N
L
S
Site 38
Y441
E
G
H
N
I
A
D
Y
I
D
P
A
I
M
K
Site 39
T461
E
K
E
E
E
L
R
T
A
A
G
E
Y
D
S
Site 40
Y466
L
R
T
A
A
G
E
Y
D
S
V
S
E
S
E
Site 41
S468
T
A
A
G
E
Y
D
S
V
S
E
S
E
D
E
Site 42
S470
A
G
E
Y
D
S
V
S
E
S
E
D
E
E
M
Site 43
S472
E
Y
D
S
V
S
E
S
E
D
E
E
M
L
E
Site 44
S498
K
K
L
K
I
L
E
S
K
E
K
N
T
Q
G
Site 45
T511
Q
G
P
R
M
P
R
T
A
K
K
V
Q
R
T
Site 46
S526
V
L
E
K
E
M
R
S
L
G
V
D
M
D
D
Site 47
Y539
D
D
K
D
D
A
H
Y
A
V
Q
A
R
R
S
Site 48
S546
Y
A
V
Q
A
R
R
S
R
S
I
T
R
K
R
Site 49
S548
V
Q
A
R
R
S
R
S
I
T
R
K
R
K
R
Site 50
T550
A
R
R
S
R
S
I
T
R
K
R
K
R
E
D
Site 51
S558
R
K
R
K
R
E
D
S
A
P
P
S
S
V
A
Site 52
S562
R
E
D
S
A
P
P
S
S
V
A
R
S
G
S
Site 53
S563
E
D
S
A
P
P
S
S
V
A
R
S
G
S
C
Site 54
S567
P
P
S
S
V
A
R
S
G
S
C
S
R
T
P
Site 55
S569
S
S
V
A
R
S
G
S
C
S
R
T
P
R
D
Site 56
S571
V
A
R
S
G
S
C
S
R
T
P
R
D
V
S
Site 57
T573
R
S
G
S
C
S
R
T
P
R
D
V
S
G
L
Site 58
S578
S
R
T
P
R
D
V
S
G
L
R
D
V
K
M
Site 59
S623
M
K
P
K
H
L
L
S
G
K
R
K
A
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation