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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBL1XR1
Full Name:
F-box-like/WD repeat-containing protein TBL1XR1
Alias:
C21; DC42; F-box-like/WD-repeat protein TBL1XR1; FLJ12894; IRA1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1R; TBL1-related protein 1; TBLR1; Transducin (beta)-like 1 X-linked receptor 1; Transducin beta-like 1X-linked receptor 1; Transducin beta-like 1X-related protein 1
Type:
Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Mass (Da):
55595
Number AA:
514
UniProt ID:
Q9BZK7
International Prot ID:
IPI00002922
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005876
GO:0017053
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0008013
GO:0042393
GO:0010843
PhosphoSite+
KinaseNET
Biological Process:
GO:0060070
GO:0016568
GO:0010553
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
V
N
F
L
V
Y
R
Y
L
Q
E
S
G
F
S
Site 2
S19
V
Y
R
Y
L
Q
E
S
G
F
S
H
S
A
F
Site 3
S22
Y
L
Q
E
S
G
F
S
H
S
A
F
T
F
G
Site 4
S24
Q
E
S
G
F
S
H
S
A
F
T
F
G
I
E
Site 5
S35
F
G
I
E
S
H
I
S
Q
S
N
I
N
G
A
Site 6
S65
Q
Y
V
E
A
E
V
S
I
N
E
D
G
T
L
Site 7
T71
V
S
I
N
E
D
G
T
L
F
D
G
R
P
I
Site 8
S119
A
A
A
A
A
A
A
S
Q
Q
G
S
A
K
N
Site 9
S123
A
A
A
S
Q
Q
G
S
A
K
N
G
E
N
T
Site 10
S186
P
V
S
D
L
L
A
S
G
S
G
D
S
T
A
Site 11
S188
S
D
L
L
A
S
G
S
G
D
S
T
A
R
I
Site 12
S191
L
A
S
G
S
G
D
S
T
A
R
I
W
N
L
Site 13
T192
A
S
G
S
G
D
S
T
A
R
I
W
N
L
S
Site 14
S199
T
A
R
I
W
N
L
S
E
N
S
T
S
G
S
Site 15
S202
I
W
N
L
S
E
N
S
T
S
G
S
T
Q
L
Site 16
T203
W
N
L
S
E
N
S
T
S
G
S
T
Q
L
V
Site 17
S204
N
L
S
E
N
S
T
S
G
S
T
Q
L
V
L
Site 18
S206
S
E
N
S
T
S
G
S
T
Q
L
V
L
R
H
Site 19
S224
E
G
G
Q
D
V
P
S
N
K
D
V
T
S
L
Site 20
S230
P
S
N
K
D
V
T
S
L
D
W
N
S
E
G
Site 21
S235
V
T
S
L
D
W
N
S
E
G
T
L
L
A
T
Site 22
T253
D
G
F
A
R
I
W
T
K
D
G
N
L
A
S
Site 23
S260
T
K
D
G
N
L
A
S
T
L
G
Q
H
K
G
Site 24
S283
K
K
G
N
F
I
L
S
A
G
V
D
K
T
T
Site 25
T290
S
A
G
V
D
K
T
T
I
I
W
D
A
H
T
Site 26
T344
G
Q
D
R
P
I
K
T
F
Q
G
H
T
N
E
Site 27
S366
P
T
G
N
L
L
A
S
C
S
D
D
M
T
L
Site 28
T396
A
H
N
K
E
I
Y
T
I
K
W
S
P
T
G
Site 29
S400
E
I
Y
T
I
K
W
S
P
T
G
P
G
T
N
Site 30
T406
W
S
P
T
G
P
G
T
N
N
P
N
A
N
L
Site 31
T423
A
S
A
S
F
D
S
T
V
R
L
W
D
V
D
Site 32
T439
G
I
C
I
H
T
L
T
K
H
Q
E
P
V
Y
Site 33
Y446
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Site 34
S447
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
G
Site 35
Y456
A
F
S
P
D
G
R
Y
L
A
S
G
S
F
D
Site 36
S461
G
R
Y
L
A
S
G
S
F
D
K
C
V
H
I
Site 37
S479
Q
T
G
A
L
V
H
S
Y
R
G
T
G
G
I
Site 38
S501
A
G
D
K
V
G
A
S
A
S
D
G
S
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation