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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM129A
Full Name:
Protein Niban
Alias:
cell growth inhibiting protein 39; NIBA; NIBAN
Type:
Protein synthesis regulatory protein; Cytoplasm
Mass (Da):
103135
Number AA:
928
UniProt ID:
Q9BZQ8
International Prot ID:
IPI00328350
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0001933
GO:0001934
GO:0045727
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
G
G
S
A
S
S
Q
L
D
E
Site 2
Y16
L
D
E
G
K
C
A
Y
I
R
G
K
T
E
A
Site 3
T21
C
A
Y
I
R
G
K
T
E
A
A
I
K
N
F
Site 4
S29
E
A
A
I
K
N
F
S
P
Y
Y
S
R
Q
Y
Site 5
Y31
A
I
K
N
F
S
P
Y
Y
S
R
Q
Y
S
V
Site 6
Y32
I
K
N
F
S
P
Y
Y
S
R
Q
Y
S
V
A
Site 7
S33
K
N
F
S
P
Y
Y
S
R
Q
Y
S
V
A
F
Site 8
Y36
S
P
Y
Y
S
R
Q
Y
S
V
A
F
C
N
H
Site 9
S37
P
Y
Y
S
R
Q
Y
S
V
A
F
C
N
H
V
Site 10
T55
V
E
Q
Q
R
D
L
T
S
Q
F
L
K
T
K
Site 11
S56
E
Q
Q
R
D
L
T
S
Q
F
L
K
T
K
P
Site 12
T61
L
T
S
Q
F
L
K
T
K
P
P
L
A
P
G
Site 13
S77
I
L
Y
E
A
E
L
S
Q
F
S
E
D
I
K
Site 14
Y90
I
K
K
W
K
E
R
Y
V
V
V
K
N
D
Y
Site 15
Y97
Y
V
V
V
K
N
D
Y
A
V
E
S
Y
E
N
Site 16
S101
K
N
D
Y
A
V
E
S
Y
E
N
K
E
A
Y
Site 17
Y108
S
Y
E
N
K
E
A
Y
Q
R
G
A
A
P
K
Site 18
Y132
V
L
T
S
E
D
E
Y
N
L
L
S
D
R
H
Site 19
S136
E
D
E
Y
N
L
L
S
D
R
H
F
P
D
P
Site 20
S147
F
P
D
P
L
A
S
S
E
K
E
N
T
Q
P
Site 21
T152
A
S
S
E
K
E
N
T
Q
P
F
V
V
L
P
Site 22
Y165
L
P
K
E
F
P
V
Y
L
W
Q
P
F
F
R
Site 23
S188
A
A
D
Q
K
R
F
S
A
L
L
S
D
C
V
Site 24
S192
K
R
F
S
A
L
L
S
D
C
V
R
H
L
N
Site 25
Y202
V
R
H
L
N
H
D
Y
M
K
Q
M
T
F
E
Site 26
Y227
F
R
Q
E
K
G
H
Y
G
S
W
E
M
I
T
Site 27
T271
K
K
N
D
R
K
R
T
W
L
G
L
L
E
E
Site 28
T281
G
L
L
E
E
A
Y
T
L
V
Q
H
Q
V
S
Site 29
S292
H
Q
V
S
E
G
L
S
A
L
K
E
E
C
R
Site 30
T302
K
E
E
C
R
A
L
T
K
G
L
E
G
T
I
Site 31
S311
G
L
E
G
T
I
R
S
D
M
D
Q
I
V
N
Site 32
S338
V
A
Q
P
A
E
K
S
C
L
E
S
V
Q
P
Site 33
S342
A
E
K
S
C
L
E
S
V
Q
P
F
L
A
S
Site 34
S349
S
V
Q
P
F
L
A
S
I
L
E
E
L
M
G
Site 35
S359
E
E
L
M
G
P
V
S
S
G
F
S
E
V
R
Site 36
S377
E
K
E
V
N
E
V
S
Q
N
F
Q
T
T
K
Site 37
S386
N
F
Q
T
T
K
D
S
V
Q
L
K
E
H
L
Site 38
Y410
S
V
K
M
E
P
C
Y
T
K
V
N
L
L
H
Site 39
T411
V
K
M
E
P
C
Y
T
K
V
N
L
L
H
E
Site 40
S425
E
R
L
Q
D
L
K
S
R
F
R
F
P
H
I
Site 41
S459
F
T
F
E
Q
L
L
S
P
H
L
Q
G
E
A
Site 42
S467
P
H
L
Q
G
E
A
S
K
T
A
V
A
I
E
Site 43
Y484
K
L
R
V
L
K
Q
Y
D
Y
D
S
S
T
I
Site 44
Y486
R
V
L
K
Q
Y
D
Y
D
S
S
T
I
R
K
Site 45
S488
L
K
Q
Y
D
Y
D
S
S
T
I
R
K
K
I
Site 46
S489
K
Q
Y
D
Y
D
S
S
T
I
R
K
K
I
F
Site 47
T490
Q
Y
D
Y
D
S
S
T
I
R
K
K
I
F
Q
Site 48
Y523
C
K
P
E
L
Q
K
Y
E
Q
F
I
F
A
D
Site 49
S577
E
D
N
M
A
L
P
S
E
S
V
S
S
L
T
Site 50
S579
N
M
A
L
P
S
E
S
V
S
S
L
T
D
L
Site 51
S581
A
L
P
S
E
S
V
S
S
L
T
D
L
K
P
Site 52
S582
L
P
S
E
S
V
S
S
L
T
D
L
K
P
P
Site 53
T584
S
E
S
V
S
S
L
T
D
L
K
P
P
T
G
Site 54
T590
L
T
D
L
K
P
P
T
G
S
N
Q
A
S
P
Site 55
S592
D
L
K
P
P
T
G
S
N
Q
A
S
P
A
R
Site 56
S596
P
T
G
S
N
Q
A
S
P
A
R
R
A
S
A
Site 57
S602
A
S
P
A
R
R
A
S
A
I
L
P
G
V
L
Site 58
S611
I
L
P
G
V
L
G
S
E
T
L
S
N
E
V
Site 59
T613
P
G
V
L
G
S
E
T
L
S
N
E
V
F
Q
Site 60
S615
V
L
G
S
E
T
L
S
N
E
V
F
Q
E
S
Site 61
S622
S
N
E
V
F
Q
E
S
E
E
E
K
Q
P
E
Site 62
S633
K
Q
P
E
V
P
S
S
L
A
K
G
E
S
L
Site 63
S639
S
S
L
A
K
G
E
S
L
S
L
P
G
P
S
Site 64
S641
L
A
K
G
E
S
L
S
L
P
G
P
S
P
P
Site 65
S646
S
L
S
L
P
G
P
S
P
P
P
D
G
T
E
Site 66
T652
P
S
P
P
P
D
G
T
E
Q
V
I
I
S
R
Site 67
T679
D
T
A
G
L
P
G
T
C
S
S
E
L
E
F
Site 68
S682
G
L
P
G
T
C
S
S
E
L
E
F
G
G
T
Site 69
T689
S
E
L
E
F
G
G
T
L
E
D
E
E
P
A
Site 70
T704
Q
E
E
P
E
P
I
T
A
S
G
S
L
K
A
Site 71
S706
E
P
E
P
I
T
A
S
G
S
L
K
A
L
R
Site 72
S726
S
V
E
V
P
V
D
S
A
P
V
M
E
E
D
Site 73
T734
A
P
V
M
E
E
D
T
N
G
E
S
H
V
P
Site 74
S738
E
E
D
T
N
G
E
S
H
V
P
Q
E
N
E
Site 75
S753
E
E
E
E
K
E
P
S
Q
A
A
A
I
H
P
Site 76
S766
H
P
D
N
C
E
E
S
E
V
S
E
R
E
A
Site 77
S769
N
C
E
E
S
E
V
S
E
R
E
A
Q
P
P
Site 78
S793
G
G
F
P
E
V
G
S
P
A
S
P
P
A
S
Site 79
S796
P
E
V
G
S
P
A
S
P
P
A
S
G
G
L
Site 80
S800
S
P
A
S
P
P
A
S
G
G
L
T
E
E
P
Site 81
T804
P
P
A
S
G
G
L
T
E
E
P
L
G
P
M
Site 82
T823
P
G
E
A
C
T
L
T
A
H
E
G
R
G
G
Site 83
T833
E
G
R
G
G
K
C
T
E
E
G
D
A
S
Q
Site 84
S839
C
T
E
E
G
D
A
S
Q
Q
E
G
C
T
L
Site 85
S848
Q
E
G
C
T
L
G
S
D
P
I
C
L
S
E
Site 86
S854
G
S
D
P
I
C
L
S
E
S
Q
V
S
E
E
Site 87
S856
D
P
I
C
L
S
E
S
Q
V
S
E
E
Q
E
Site 88
S859
C
L
S
E
S
Q
V
S
E
E
Q
E
E
M
G
Site 89
S870
E
E
M
G
G
Q
S
S
A
A
Q
A
T
A
S
Site 90
S877
S
A
A
Q
A
T
A
S
V
N
A
E
E
I
K
Site 91
S906
P
N
P
D
V
L
L
S
H
K
D
D
V
K
E
Site 92
S920
E
G
E
G
G
Q
E
S
F
P
E
L
P
S
E
Site 93
S926
E
S
F
P
E
L
P
S
E
E
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation