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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
API5
Full Name:
Apoptosis inhibitor 5
Alias:
AAC11; AAC-11; API-5; API5L1; API5-like 1; Apoptosis inhibitor 5: Fibroblast growth factor 2-interacting factor: Protein XAGL: Antiapoptosis clone 11 protein: Cell migration-inducing gene 8 protein: Apoptosis inhibitor 5: Fibroblast growth factor 2-interacting factor: Protein XAGL: Antiapoptosis clone 11 protein: Cell migration-inducing gene 8 protein: Apoptosis inhibitor 5: Fibroblast growth factor 2-interacting factor: Protein XAGL: Antiapoptosis clone 11 protein: Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; Fibroblast growth factor 2-interacting factor 2; FIF; Migration-inducing protein MIG8; XAGL protein
Type:
Uncharacterized protein
Mass (Da):
57561
Number AA:
510
UniProt ID:
Q9BZZ5
International Prot ID:
IPI00555572
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0017134
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
P
T
V
E
E
L
Y
R
N
Y
G
I
L
A
Site 2
Y11
V
E
E
L
Y
R
N
Y
G
I
L
A
D
A
T
Site 3
T18
Y
G
I
L
A
D
A
T
E
Q
V
G
Q
H
K
Site 4
Y28
V
G
Q
H
K
D
A
Y
Q
V
I
L
D
G
V
Site 5
S62
H
F
P
E
L
A
D
S
A
I
N
A
Q
L
D
Site 6
S77
L
C
E
D
E
D
V
S
I
R
R
Q
A
I
K
Site 7
T103
P
R
V
A
D
I
L
T
Q
L
L
Q
T
D
D
Site 8
S111
Q
L
L
Q
T
D
D
S
A
E
F
N
L
V
N
Site 9
S156
E
R
A
I
K
F
L
S
T
K
L
K
T
L
P
Site 10
T177
E
V
E
E
L
I
L
T
E
S
K
K
V
L
E
Site 11
S179
E
E
L
I
L
T
E
S
K
K
V
L
E
D
V
Site 12
S203
K
I
L
S
G
L
K
S
L
Q
T
V
S
G
R
Site 13
T206
S
G
L
K
S
L
Q
T
V
S
G
R
Q
Q
L
Site 14
S208
L
K
S
L
Q
T
V
S
G
R
Q
Q
L
V
E
Site 15
T226
E
Q
A
D
L
E
Q
T
F
N
P
S
D
P
D
Site 16
S230
L
E
Q
T
F
N
P
S
D
P
D
C
V
D
R
Site 17
S250
R
Q
A
V
P
L
F
S
K
N
V
H
S
T
R
Site 18
Y261
H
S
T
R
F
V
T
Y
F
C
E
Q
V
L
P
Site 19
S295
K
L
L
A
E
M
S
S
F
C
G
D
M
E
K
Site 20
T305
G
D
M
E
K
L
E
T
N
L
R
K
L
F
D
Site 21
Y317
L
F
D
K
L
L
E
Y
M
P
L
P
P
E
E
Site 22
S341
E
E
P
K
L
Q
F
S
Y
V
E
C
L
L
Y
Site 23
Y342
E
P
K
L
Q
F
S
Y
V
E
C
L
L
Y
S
Site 24
Y348
S
Y
V
E
C
L
L
Y
S
F
H
Q
L
G
R
Site 25
T362
R
K
L
P
D
F
L
T
A
K
L
N
A
E
K
Site 26
Y379
D
F
K
I
R
L
Q
Y
F
A
R
G
L
Q
V
Site 27
T405
K
T
G
E
A
L
K
T
E
E
N
K
I
K
V
Site 28
S434
D
L
F
H
I
P
P
S
Y
K
S
T
V
T
L
Site 29
S437
H
I
P
P
S
Y
K
S
T
V
T
L
S
W
K
Site 30
T438
I
P
P
S
Y
K
S
T
V
T
L
S
W
K
P
Site 31
T440
P
S
Y
K
S
T
V
T
L
S
W
K
P
V
Q
Site 32
S442
Y
K
S
T
V
T
L
S
W
K
P
V
Q
K
V
Site 33
S457
E
I
G
Q
K
R
A
S
E
D
T
T
S
G
S
Site 34
T460
Q
K
R
A
S
E
D
T
T
S
G
S
P
P
K
Site 35
T461
K
R
A
S
E
D
T
T
S
G
S
P
P
K
K
Site 36
S462
R
A
S
E
D
T
T
S
G
S
P
P
K
K
S
Site 37
S464
S
E
D
T
T
S
G
S
P
P
K
K
S
S
A
Site 38
S469
S
G
S
P
P
K
K
S
S
A
G
P
K
R
D
Site 39
S470
G
S
P
P
K
K
S
S
A
G
P
K
R
D
A
Site 40
Y481
K
R
D
A
R
Q
I
Y
N
P
P
S
G
K
Y
Site 41
S485
R
Q
I
Y
N
P
P
S
G
K
Y
S
S
N
L
Site 42
Y488
Y
N
P
P
S
G
K
Y
S
S
N
L
G
N
F
Site 43
S489
N
P
P
S
G
K
Y
S
S
N
L
G
N
F
N
Site 44
S490
P
P
S
G
K
Y
S
S
N
L
G
N
F
N
Y
Site 45
Y497
S
N
L
G
N
F
N
Y
G
E
R
F
R
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation