PhosphoNET

           
Protein Info 
   
Short Name:  SPRY4
Full Name:  Protein sprouty homolog 4
Alias:  sprouty 4; Spry-4; SPY4
Type:  Inhibitor protein; Adaptor/scaffold
Mass (Da):  32541
Number AA:  299
UniProt ID:  Q9C004
International Prot ID:  IPI00307426
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0042995  GO:0005737  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0007275     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MEPPIPQSAPLTPNS
Site 2S24MVQPLLDSRMSHSRL
Site 3S27PLLDSRMSHSRLQHP
Site 4Y52TSHVENDYIDNPSLA
Site 5S57NDYIDNPSLALTTGP
Site 6T61DNPSLALTTGPKRTR
Site 7T77GAPELAPTPARCDQD
Site 8S91DVTHHWISFSGRPSS
Site 9S93THHWISFSGRPSSVS
Site 10S97ISFSGRPSSVSSSSS
Site 11S98SFSGRPSSVSSSSST
Site 12S100SGRPSSVSSSSSTSS
Site 13S101GRPSSVSSSSSTSSD
Site 14S102RPSSVSSSSSTSSDQ
Site 15S103PSSVSSSSSTSSDQR
Site 16S104SSVSSSSSTSSDQRL
Site 17T105SVSSSSSTSSDQRLL
Site 18S106VSSSSSTSSDQRLLD
Site 19S107SSSSSTSSDQRLLDH
Site 20S125MEIGDTLSTAEESSP
Site 21S172CKCKECASPRTLPSC
Site 22T175KECASPRTLPSCWVC
Site 23S218TNEDDEGSCADHPCS
Site 24Y265VKLAQRGYDRLRRPG
Site 25T292AASGDAKTSRPDKPF
Site 26S293ASGDAKTSRPDKPF_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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