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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM6
Full Name:
Tripartite motif-containing protein 6
Alias:
RING finger protein 89
Type:
Mass (Da):
56400
Number AA:
488
UniProt ID:
Q9C030
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T40
S
F
C
Q
A
C
I
T
P
N
G
R
E
S
V
Site 2
S46
I
T
P
N
G
R
E
S
V
I
G
Q
E
G
E
Site 3
S55
I
G
Q
E
G
E
R
S
C
P
V
C
Q
T
S
Site 4
S62
S
C
P
V
C
Q
T
S
Y
Q
P
G
N
L
R
Site 5
T130
Q
E
H
R
G
H
H
T
F
L
V
E
E
V
A
Site 6
Y140
V
E
E
V
A
Q
E
Y
Q
E
K
F
Q
E
S
Site 7
T185
P
E
R
C
R
I
Q
T
E
F
N
Q
L
R
N
Site 8
S229
D
L
V
H
Q
T
Q
S
L
R
E
L
I
S
D
Site 9
S235
Q
S
L
R
E
L
I
S
D
L
E
R
R
C
Q
Site 10
S244
L
E
R
R
C
Q
G
S
T
M
E
L
L
Q
D
Site 11
T245
E
R
R
C
Q
G
S
T
M
E
L
L
Q
D
V
Site 12
S253
M
E
L
L
Q
D
V
S
D
V
T
E
R
S
E
Site 13
T256
L
Q
D
V
S
D
V
T
E
R
S
E
F
W
T
Site 14
T263
T
E
R
S
E
F
W
T
L
R
K
P
E
A
L
Site 15
T272
R
K
P
E
A
L
P
T
K
L
R
S
M
F
R
Site 16
S276
A
L
P
T
K
L
R
S
M
F
R
A
P
D
L
Site 17
T294
L
R
V
C
R
E
L
T
D
V
Q
S
Y
W
V
Site 18
S298
R
E
L
T
D
V
Q
S
Y
W
V
D
V
T
L
Site 19
S331
R
F
V
G
A
K
V
S
G
P
S
C
L
E
K
Site 20
Y340
P
S
C
L
E
K
H
Y
D
C
S
V
L
G
S
Site 21
S343
L
E
K
H
Y
D
C
S
V
L
G
S
Q
H
F
Site 22
S347
Y
D
C
S
V
L
G
S
Q
H
F
S
S
G
K
Site 23
S351
V
L
G
S
Q
H
F
S
S
G
K
H
Y
W
E
Site 24
Y356
H
F
S
S
G
K
H
Y
W
E
V
D
V
A
K
Site 25
T379
C
S
N
S
L
G
P
T
F
S
F
N
H
F
A
Site 26
S381
N
S
L
G
P
T
F
S
F
N
H
F
A
Q
N
Site 27
Y392
F
A
Q
N
H
S
A
Y
S
R
Y
Q
P
Q
S
Site 28
Y395
N
H
S
A
Y
S
R
Y
Q
P
Q
S
G
Y
W
Site 29
Y401
R
Y
Q
P
Q
S
G
Y
W
V
I
G
L
Q
H
Site 30
Y415
H
N
H
E
Y
R
A
Y
E
D
S
S
P
S
L
Site 31
S418
E
Y
R
A
Y
E
D
S
S
P
S
L
L
L
S
Site 32
S419
Y
R
A
Y
E
D
S
S
P
S
L
L
L
S
M
Site 33
S425
S
S
P
S
L
L
L
S
M
T
V
P
P
R
R
Site 34
Y447
E
A
G
T
V
S
F
Y
N
V
T
N
H
G
F
Site 35
Y457
T
N
H
G
F
P
I
Y
T
F
S
K
Y
Y
F
Site 36
T458
N
H
G
F
P
I
Y
T
F
S
K
Y
Y
F
P
Site 37
T482
C
N
C
V
I
P
M
T
L
R
R
P
S
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation