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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM4
Full Name:
Tripartite motif-containing protein 4
Alias:
RING finger protein 87
Type:
Mass (Da):
57461
Number AA:
500
UniProt ID:
Q9C037
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
E
D
I
Q
E
E
L
T
C
P
I
C
L
D
Y
Site 2
S56
C
P
E
C
R
H
P
S
A
P
A
A
L
R
P
Site 3
T71
N
W
A
L
A
R
L
T
E
K
T
Q
R
R
R
Site 4
T74
L
A
R
L
T
E
K
T
Q
R
R
R
L
G
P
Site 5
S129
P
I
D
E
A
F
E
S
Y
R
T
G
N
F
D
Site 6
T132
E
A
F
E
S
Y
R
T
G
N
F
D
I
H
V
Site 7
Y152
R
L
I
R
L
L
L
Y
H
F
K
Q
E
E
K
Site 8
S163
Q
E
E
K
L
L
K
S
Q
R
N
L
V
A
K
Site 9
S200
K
S
Q
R
M
R
I
S
T
E
F
S
K
L
H
Site 10
T201
S
Q
R
M
R
I
S
T
E
F
S
K
L
H
N
Site 11
S257
I
L
E
V
G
E
K
S
Q
A
P
T
L
E
L
Site 12
T261
G
E
K
S
Q
A
P
T
L
E
L
L
Q
N
P
Site 13
S275
P
K
E
V
L
T
R
S
E
I
Q
D
V
N
Y
Site 14
Y282
S
E
I
Q
D
V
N
Y
S
L
E
A
V
K
V
Site 15
S323
A
H
P
K
L
V
F
S
Q
E
G
R
Y
V
K
Site 16
Y328
V
F
S
Q
E
G
R
Y
V
K
N
T
A
S
A
Site 17
T332
E
G
R
Y
V
K
N
T
A
S
A
S
S
W
P
Site 18
S334
R
Y
V
K
N
T
A
S
A
S
S
W
P
V
F
Site 19
S336
V
K
N
T
A
S
A
S
S
W
P
V
F
S
S
Site 20
S337
K
N
T
A
S
A
S
S
W
P
V
F
S
S
A
Site 21
T357
G
W
R
N
P
Q
K
T
A
F
V
E
R
F
Q
Site 22
Y381
V
F
T
S
G
K
H
Y
W
E
V
E
S
R
D
Site 23
S389
W
E
V
E
S
R
D
S
L
E
V
A
V
G
V
Site 24
T405
R
E
D
V
M
G
I
T
D
R
S
K
M
S
P
Site 25
S408
V
M
G
I
T
D
R
S
K
M
S
P
D
V
G
Site 26
S411
I
T
D
R
S
K
M
S
P
D
V
G
I
W
A
Site 27
T435
P
L
I
G
F
P
G
T
P
T
Q
Q
E
P
A
Site 28
Y449
A
L
H
R
V
G
V
Y
L
D
R
G
T
G
N
Site 29
T454
G
V
Y
L
D
R
G
T
G
N
V
S
F
Y
S
Site 30
S458
D
R
G
T
G
N
V
S
F
Y
S
A
V
D
G
Site 31
S474
H
L
H
T
F
S
C
S
S
V
S
R
L
R
P
Site 32
S475
L
H
T
F
S
C
S
S
V
S
R
L
R
P
F
Site 33
S477
T
F
S
C
S
S
V
S
R
L
R
P
F
F
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation