PhosphoNET

           
Protein Info 
   
Short Name:  SETD5
Full Name:  SET domain-containing protein 5
Alias:  KIAA1757
Type:  Unknown function
Mass (Da):  157515
Number AA:  1442
UniProt ID:  Q9C0A6
International Prot ID:  IPI00741882
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T11AIPLGVTTSDTSYSD
Site 2S12IPLGVTTSDTSYSDM
Site 3S15GVTTSDTSYSDMAAG
Site 4Y16VTTSDTSYSDMAAGS
Site 5S17TTSDTSYSDMAAGSD
Site 6S23YSDMAAGSDPESVEA
Site 7S27AAGSDPESVEASPAV
Site 8S31DPESVEASPAVNEKS
Site 9S38SPAVNEKSVYSTHNY
Site 10Y40AVNEKSVYSTHNYGT
Site 11T42NEKSVYSTHNYGTTQ
Site 12Y45SVYSTHNYGTTQRHG
Site 13T48STHNYGTTQRHGCRG
Site 14Y58HGCRGLPYATIIPRS
Site 15S65YATIIPRSDLNGLPS
Site 16S72SDLNGLPSPVEERCG
Site 17S81VEERCGDSPNSEGET
Site 18S84RCGDSPNSEGETVPT
Site 19T88SPNSEGETVPTWCPC
Site 20T91SEGETVPTWCPCGLS
Site 21S113CDKCRGMSRGKVIRL
Site 22S129RRKQDNISGGDSSAT
Site 23S133DNISGGDSSATESWD
Site 24S134NISGGDSSATESWDE
Site 25T136SGGDSSATESWDEEL
Site 26S138GDSSATESWDEELSP
Site 27S144ESWDEELSPSTVLYT
Site 28S146WDEELSPSTVLYTAT
Site 29Y150LSPSTVLYTATQHTP
Site 30T156LYTATQHTPTSITLT
Site 31S159ATQHTPTSITLTVRR
Site 32T163TPTSITLTVRRTKPK
Site 33T167ITLTVRRTKPKKRKK
Site 34S175KPKKRKKSPEKGRAA
Site 35T185KGRAAPKTKKIKNSP
Site 36S191KTKKIKNSPSEAQNL
Site 37S193KKIKNSPSEAQNLDE
Site 38T214ENRIRLWTDQYEEAF
Site 39Y217IRLWTDQYEEAFTNQ
Site 40T222DQYEEAFTNQYSADV
Site 41T252GKPTILDTINKTELA
Site 42T263TELACNNTVIGSQMQ
Site 43T277QLQLGRVTRVQKHRK
Site 44Y322GHFFKKPYPFVLFYS
Site 45S353DARFIRRSCTPNAEV
Site 46T355RFIRRSCTPNAEVRH
Site 47Y391EVTIAFDYEYSNCNY
Site 48Y393TIAFDYEYSNCNYKV
Site 49T421QKRNPNATELPLLPP
Site 50S466EENNDQQSQEVPEKV
Site 51T474QEVPEKVTVSSDHEE
Site 52S506DQENLAHSRRTREDR
Site 53T509NLAHSRRTREDRKVE
Site 54S539RDQPLEQSNSDVEIT
Site 55S541QPLEQSNSDVEITTT
Site 56T548SDVEITTTTSETPVG
Site 57S550VEITTTTSETPVGEE
Site 58T552ITTTTSETPVGEETK
Site 59T560PVGEETKTEAPESEV
Site 60S565TKTEAPESEVSNSVS
Site 61S568EAPESEVSNSVSNVT
Site 62S570PESEVSNSVSNVTIP
Site 63S572SEVSNSVSNVTIPST
Site 64T575SNSVSNVTIPSTPQS
Site 65T579SNVTIPSTPQSVGVN
Site 66S582TIPSTPQSVGVNTRR
Site 67T587PQSVGVNTRRSSQAG
Site 68S590VGVNTRRSSQAGDIA
Site 69S591GVNTRRSSQAGDIAA
Site 70S611KPPPAKPSRPRPKSR
Site 71S617PSRPRPKSRISRYRT
Site 72S620PRPKSRISRYRTSSA
Site 73Y622PKSRISRYRTSSAQR
Site 74T624SRISRYRTSSAQRLK
Site 75S625RISRYRTSSAQRLKR
Site 76S626ISRYRTSSAQRLKRQ
Site 77S644NAQQAELSQAALEEG
Site 78S653AALEEGGSNSLVTPT
Site 79S655LEEGGSNSLVTPTEA
Site 80T658GGSNSLVTPTEAGSL
Site 81T660SNSLVTPTEAGSLDS
Site 82S664VTPTEAGSLDSSGEN
Site 83S668EAGSLDSSGENRPLT
Site 84T675SGENRPLTGSDPTVV
Site 85S677ENRPLTGSDPTVVSI
Site 86S683GSDPTVVSITGSHVN
Site 87S694SHVNRAASKYPKTKK
Site 88Y696VNRAASKYPKTKKYL
Site 89T699AASKYPKTKKYLVTE
Site 90Y702KYPKTKKYLVTEWLN
Site 91Y755ICTTPKHYIRFGSPF
Site 92S760KHYIRFGSPFIPERR
Site 93T776RPLLPDGTFSSCKKR
Site 94S778LLPDGTFSSCKKRWI
Site 95S779LPDGTFSSCKKRWIK
Site 96T794QALEEGMTQTSSVPQ
Site 97S798EGMTQTSSVPQETRT
Site 98Y809ETRTQHLYQSNENSS
Site 99S811RTQHLYQSNENSSSS
Site 100S815LYQSNENSSSSSICK
Site 101S816YQSNENSSSSSICKD
Site 102S817QSNENSSSSSICKDN
Site 103S819NENSSSSSICKDNAD
Site 104S829KDNADLLSPLKKWKS
Site 105S836SPLKKWKSRYLMEQN
Site 106Y838LKKWKSRYLMEQNVT
Site 107T845YLMEQNVTKLLRPLS
Site 108S852TKLLRPLSPVTPPPP
Site 109T855LRPLSPVTPPPPNSG
Site 110S861VTPPPPNSGSKSPQL
Site 111S863PPPPNSGSKSPQLAT
Site 112S865PPNSGSKSPQLATPG
Site 113T870SKSPQLATPGSSHPG
Site 114S873PQLATPGSSHPGEEE
Site 115Y885EEECRNGYSLMFSPV
Site 116S886EECRNGYSLMFSPVT
Site 117S890NGYSLMFSPVTSLTT
Site 118T896FSPVTSLTTASRCNT
Site 119S899VTSLTTASRCNTPLQ
Site 120T903TTASRCNTPLQFELC
Site 121Y922LDLAKVGYLDSNTNS
Site 122S925AKVGYLDSNTNSCAD
Site 123T927VGYLDSNTNSCADRP
Site 124S929YLDSNTNSCADRPSL
Site 125S935NSCADRPSLLNSGHS
Site 126S939DRPSLLNSGHSDLAP
Site 127S942SLLNSGHSDLAPHPS
Site 128S949SDLAPHPSLGPTSET
Site 129T953PHPSLGPTSETGFPS
Site 130S954HPSLGPTSETGFPSR
Site 131T956SLGPTSETGFPSRSG
Site 132S960TSETGFPSRSGDGHQ
Site 133T968RSGDGHQTLVRNSDQ
Site 134S973HQTLVRNSDQAFRTE
Site 135Y985RTEFNLMYAYSPLNA
Site 136Y987EFNLMYAYSPLNAMP
Site 137S988FNLMYAYSPLNAMPR
Site 138Y1000MPRADGLYRGSPLVG
Site 139S1003ADGLYRGSPLVGDRK
Site 140Y1018PLHLDGGYCSPAEGF
Site 141S1020HLDGGYCSPAEGFSS
Site 142S1026CSPAEGFSSRYEHGL
Site 143S1027SPAEGFSSRYEHGLM
Site 144Y1029AEGFSSRYEHGLMKD
Site 145S1038HGLMKDLSRGSLSPG
Site 146S1041MKDLSRGSLSPGGER
Site 147S1043DLSRGSLSPGGERAC
Site 148S1055RACEGVPSAPQNPPQ
Site 149Y1071KKVSLLEYRKRKQEA
Site 150S1089SAGGGGDSAQSKSKS
Site 151S1092GGGDSAQSKSKSAGA
Site 152S1094GDSAQSKSKSAGAGQ
Site 153S1096SAQSKSKSAGAGQGS
Site 154S1103SAGAGQGSSNSVSDT
Site 155S1104AGAGQGSSNSVSDTG
Site 156S1106AGQGSSNSVSDTGAH
Site 157S1108QGSSNSVSDTGAHGV
Site 158T1110SSNSVSDTGAHGVQG
Site 159S1118GAHGVQGSSARTPSS
Site 160S1119AHGVQGSSARTPSSP
Site 161T1122VQGSSARTPSSPHKK
Site 162S1124GSSARTPSSPHKKFS
Site 163S1125SSARTPSSPHKKFSP
Site 164S1131SSPHKKFSPSHSSMS
Site 165S1133PHKKFSPSHSSMSHL
Site 166S1135KKFSPSHSSMSHLEA
Site 167S1136KFSPSHSSMSHLEAV
Site 168S1138SPSHSSMSHLEAVSP
Site 169S1144MSHLEAVSPSDSRGT
Site 170S1146HLEAVSPSDSRGTSS
Site 171S1148EAVSPSDSRGTSSSH
Site 172T1151SPSDSRGTSSSHCRP
Site 173S1152PSDSRGTSSSHCRPQ
Site 174S1153SDSRGTSSSHCRPQE
Site 175S1154DSRGTSSSHCRPQEN
Site 176S1164RPQENISSRWMVPTS
Site 177T1170SSRWMVPTSVERLRE
Site 178S1171SRWMVPTSVERLREG
Site 179S1180ERLREGGSIPKVLRS
Site 180S1187SIPKVLRSSVRVAQK
Site 181S1188IPKVLRSSVRVAQKG
Site 182S1198VAQKGEPSPTWESNI
Site 183T1200QKGEPSPTWESNITE
Site 184T1206PTWESNITEKDSDPA
Site 185S1210SNITEKDSDPADGEG
Site 186T1220ADGEGPETLSSALSK
Site 187S1222GEGPETLSSALSKGA
Site 188S1223EGPETLSSALSKGAT
Site 189S1226ETLSSALSKGATVYS
Site 190T1230SALSKGATVYSPSRY
Site 191Y1232LSKGATVYSPSRYSY
Site 192S1233SKGATVYSPSRYSYQ
Site 193S1238VYSPSRYSYQLLQCD
Site 194Y1239YSPSRYSYQLLQCDS
Site 195S1246YQLLQCDSPRTESQS
Site 196T1249LQCDSPRTESQSLLQ
Site 197S1251CDSPRTESQSLLQQS
Site 198S1253SPRTESQSLLQQSSS
Site 199S1258SQSLLQQSSSPFRGH
Site 200S1259QSLLQQSSSPFRGHP
Site 201S1260SLLQQSSSPFRGHPT
Site 202T1267SPFRGHPTQSPGYSY
Site 203S1269FRGHPTQSPGYSYRT
Site 204S1273PTQSPGYSYRTTALR
Site 205T1277PGYSYRTTALRPGNP
Site 206S1286LRPGNPPSHGSSESS
Site 207S1289GNPPSHGSSESSLSS
Site 208S1290NPPSHGSSESSLSST
Site 209S1292PSHGSSESSLSSTSY
Site 210S1293SHGSSESSLSSTSYS
Site 211S1295GSSESSLSSTSYSSP
Site 212S1296SSESSLSSTSYSSPA
Site 213T1297SESSLSSTSYSSPAH
Site 214S1298ESSLSSTSYSSPAHP
Site 215Y1299SSLSSTSYSSPAHPV
Site 216S1300SLSSTSYSSPAHPVS
Site 217S1301LSSTSYSSPAHPVST
Site 218S1307SSPAHPVSTDSLAPF
Site 219S1310AHPVSTDSLAPFTGT
Site 220T1315TDSLAPFTGTPGYFS
Site 221T1317SLAPFTGTPGYFSSQ
Site 222Y1320PFTGTPGYFSSQPHS
Site 223S1322TGTPGYFSSQPHSGN
Site 224S1323GTPGYFSSQPHSGNS
Site 225S1327YFSSQPHSGNSTGSN
Site 226S1330SQPHSGNSTGSNLPR
Site 227T1331QPHSGNSTGSNLPRR
Site 228S1333HSGNSTGSNLPRRSC
Site 229S1339GSNLPRRSCPSSAAS
Site 230S1342LPRRSCPSSAASPTL
Site 231S1343PRRSCPSSAASPTLQ
Site 232S1346SCPSSAASPTLQGPS
Site 233T1348PSSAASPTLQGPSDS
Site 234S1353SPTLQGPSDSPTSDS
Site 235S1355TLQGPSDSPTSDSVS
Site 236T1357QGPSDSPTSDSVSQS
Site 237S1358GPSDSPTSDSVSQSS
Site 238S1360SDSPTSDSVSQSSTG
Site 239S1362SPTSDSVSQSSTGTL
Site 240S1364TSDSVSQSSTGTLSS
Site 241S1365SDSVSQSSTGTLSST
Site 242T1366DSVSQSSTGTLSSTS
Site 243T1368VSQSSTGTLSSTSFP
Site 244S1370QSSTGTLSSTSFPQN
Site 245S1371SSTGTLSSTSFPQNS
Site 246T1372STGTLSSTSFPQNSR
Site 247S1373TGTLSSTSFPQNSRS
Site 248S1378STSFPQNSRSSLPSD
Site 249S1380SFPQNSRSSLPSDLR
Site 250S1381FPQNSRSSLPSDLRT
Site 251S1384NSRSSLPSDLRTISL
Site 252T1388SLPSDLRTISLPSAG
Site 253S1390PSDLRTISLPSAGQS
Site 254S1397SLPSAGQSAVYQASR
Site 255Y1400SAGQSAVYQASRVSA
Site 256S1403QSAVYQASRVSAVSN
Site 257S1406VYQASRVSAVSNSQH
Site 258S1409ASRVSAVSNSQHYPH
Site 259S1411RVSAVSNSQHYPHRG
Site 260Y1414AVSNSQHYPHRGSGG
Site 261S1433RLQPLQGSGVKTQTG
Site 262T1437LQGSGVKTQTGLS__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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