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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM5B
Full Name:
Protein FAM5B
Alias:
BMP/retinoic acid-inducible neural-specific protein 2;DBCCR1-like protein 2
Type:
Mass (Da):
89005
Number AA:
783
UniProt ID:
Q9C0B6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S48
V
V
P
E
Q
H
A
S
V
A
G
Q
H
P
L
Site 2
T60
H
P
L
D
W
L
L
T
D
R
G
P
F
H
R
Site 3
Y71
P
F
H
R
A
Q
E
Y
A
D
F
M
E
R
Y
Site 4
Y78
Y
A
D
F
M
E
R
Y
R
Q
G
F
T
T
R
Site 5
T83
E
R
Y
R
Q
G
F
T
T
R
Y
R
I
Y
R
Site 6
T84
R
Y
R
Q
G
F
T
T
R
Y
R
I
Y
R
E
Site 7
Y86
R
Q
G
F
T
T
R
Y
R
I
Y
R
E
F
A
Site 8
Y89
F
T
T
R
Y
R
I
Y
R
E
F
A
R
W
K
Site 9
Y142
T
E
N
L
I
K
K
Y
G
T
H
F
L
L
S
Site 10
S149
Y
G
T
H
F
L
L
S
A
T
L
G
G
E
E
Site 11
T151
T
H
F
L
L
S
A
T
L
G
G
E
E
S
L
Site 12
S157
A
T
L
G
G
E
E
S
L
T
I
F
V
D
K
Site 13
T159
L
G
G
E
E
S
L
T
I
F
V
D
K
Q
K
Site 14
T171
K
Q
K
L
G
R
K
T
E
T
T
G
G
A
S
Site 15
T174
L
G
R
K
T
E
T
T
G
G
A
S
I
I
G
Site 16
S178
T
E
T
T
G
G
A
S
I
I
G
G
S
G
N
Site 17
S190
S
G
N
S
T
A
V
S
L
E
T
L
H
Q
L
Site 18
Y201
L
H
Q
L
A
A
S
Y
F
I
D
R
E
S
T
Site 19
S207
S
Y
F
I
D
R
E
S
T
L
R
R
L
H
H
Site 20
T208
Y
F
I
D
R
E
S
T
L
R
R
L
H
H
I
Site 21
S235
R
T
G
P
L
G
C
S
N
Y
D
N
L
D
S
Site 22
Y237
G
P
L
G
C
S
N
Y
D
N
L
D
S
V
S
Site 23
S242
S
N
Y
D
N
L
D
S
V
S
S
V
L
V
Q
Site 24
S244
Y
D
N
L
D
S
V
S
S
V
L
V
Q
S
P
Site 25
S245
D
N
L
D
S
V
S
S
V
L
V
Q
S
P
E
Site 26
S250
V
S
S
V
L
V
Q
S
P
E
N
K
V
Q
L
Site 27
S319
D
I
Q
A
M
E
D
S
L
L
Q
I
Q
D
S
Site 28
S326
S
L
L
Q
I
Q
D
S
W
A
T
H
N
R
Q
Site 29
S337
H
N
R
Q
F
E
E
S
E
E
F
Q
A
L
L
Site 30
S355
P
D
D
R
F
L
N
S
T
A
I
S
Q
F
W
Site 31
T356
D
D
R
F
L
N
S
T
A
I
S
Q
F
W
A
Site 32
Y372
D
T
S
L
Q
H
R
Y
Q
Q
L
G
A
G
L
Site 33
T386
L
K
V
L
F
K
K
T
H
R
I
L
R
R
L
Site 34
S413
F
R
L
P
K
E
R
S
L
S
Y
W
W
N
R
Site 35
S415
L
P
K
E
R
S
L
S
Y
W
W
N
R
I
Q
Site 36
Y426
N
R
I
Q
S
L
L
Y
C
G
E
S
T
F
P
Site 37
T435
G
E
S
T
F
P
G
T
F
L
E
Q
S
H
S
Site 38
T444
L
E
Q
S
H
S
C
T
C
P
Y
D
Q
S
S
Site 39
Y447
S
H
S
C
T
C
P
Y
D
Q
S
S
C
Q
G
Site 40
S479
D
N
S
T
R
C
G
S
C
N
P
G
Y
V
L
Site 41
Y516
L
Q
D
L
E
L
K
Y
L
L
Q
K
Q
D
S
Site 42
S523
Y
L
L
Q
K
Q
D
S
R
I
E
V
H
S
I
Site 43
S529
D
S
R
I
E
V
H
S
I
F
I
S
N
D
M
Site 44
S533
E
V
H
S
I
F
I
S
N
D
M
R
L
G
S
Site 45
S540
S
N
D
M
R
L
G
S
W
F
D
P
S
W
R
Site 46
T553
W
R
K
R
M
L
L
T
L
K
S
N
K
Y
K
Site 47
S556
R
M
L
L
T
L
K
S
N
K
Y
K
P
G
L
Site 48
Y559
L
T
L
K
S
N
K
Y
K
P
G
L
V
H
V
Site 49
S598
N
P
F
G
G
S
H
S
E
S
W
F
M
P
V
Site 50
S609
F
M
P
V
N
E
G
S
F
P
D
W
E
R
T
Site 51
T637
T
L
G
N
R
W
K
T
F
F
E
T
V
H
V
Site 52
Y645
F
F
E
T
V
H
V
Y
L
R
S
R
I
K
S
Site 53
S648
T
V
H
V
Y
L
R
S
R
I
K
S
L
D
D
Site 54
S652
Y
L
R
S
R
I
K
S
L
D
D
S
S
N
E
Site 55
S656
R
I
K
S
L
D
D
S
S
N
E
T
I
Y
Y
Site 56
S657
I
K
S
L
D
D
S
S
N
E
T
I
Y
Y
E
Site 57
T660
L
D
D
S
S
N
E
T
I
Y
Y
E
P
L
E
Site 58
Y662
D
S
S
N
E
T
I
Y
Y
E
P
L
E
M
T
Site 59
Y663
S
S
N
E
T
I
Y
Y
E
P
L
E
M
T
D
Site 60
S672
P
L
E
M
T
D
P
S
K
N
L
G
Y
M
K
Site 61
Y688
N
T
L
Q
V
F
G
Y
S
L
P
F
D
P
D
Site 62
Y706
D
L
I
L
Q
L
D
Y
P
Y
T
Q
G
S
Q
Site 63
Y708
I
L
Q
L
D
Y
P
Y
T
Q
G
S
Q
D
S
Site 64
T709
L
Q
L
D
Y
P
Y
T
Q
G
S
Q
D
S
A
Site 65
S712
D
Y
P
Y
T
Q
G
S
Q
D
S
A
L
L
Q
Site 66
S731
R
D
R
V
N
Q
L
S
P
P
G
K
V
R
L
Site 67
S761
N
E
V
G
R
I
Q
S
S
L
R
A
F
N
S
Site 68
S762
E
V
G
R
I
Q
S
S
L
R
A
F
N
S
K
Site 69
S768
S
S
L
R
A
F
N
S
K
L
P
N
P
V
E
Site 70
Y776
K
L
P
N
P
V
E
Y
E
T
G
K
L
C
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation