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Updated November 2019
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Protein Info
Short Name:
TNKS1BP1
Full Name:
182 kDa tankyrase-1-binding protein
Alias:
182 kDa tankyrase 1-binding protein; FLJ45975; KIAA1741; TAB182; TABP; Tankyrase 1 binding protein 1, 182kDa; TB182
Type:
Actin binding protein; Cell cycle regulation
Mass (Da):
181782
Number AA:
1729
UniProt ID:
Q9C0C2
International Prot ID:
IPI00304589
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005724
Uniprot
OncoNet
Molecular Function:
GO:0030506
GO:0019899
PhosphoSite+
KinaseNET
Biological Process:
GO:0007004
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
K
V
S
T
L
R
E
S
S
A
M
Site 2
S9
K
V
S
T
L
R
E
S
S
A
M
A
S
P
L
Site 3
S10
V
S
T
L
R
E
S
S
A
M
A
S
P
L
P
Site 4
S14
R
E
S
S
A
M
A
S
P
L
P
R
E
M
E
Site 5
T27
M
E
E
E
L
V
P
T
G
S
E
P
G
D
T
Site 6
S29
E
E
L
V
P
T
G
S
E
P
G
D
T
R
A
Site 7
T34
T
G
S
E
P
G
D
T
R
A
K
P
P
V
K
Site 8
S77
G
P
L
A
E
L
P
S
A
R
K
M
N
M
L
Site 9
Y90
M
L
A
G
P
Q
P
Y
G
G
S
K
R
P
L
Site 10
S93
G
P
Q
P
Y
G
G
S
K
R
P
L
P
F
A
Site 11
T131
K
E
E
P
P
P
L
T
P
P
A
R
C
A
A
Site 12
S153
P
A
P
F
R
P
A
S
E
R
F
A
A
T
T
Site 13
T159
A
S
E
R
F
A
A
T
T
V
E
E
I
L
A
Site 14
T160
S
E
R
F
A
A
T
T
V
E
E
I
L
A
K
Site 15
S178
P
R
K
E
V
L
A
S
P
D
R
L
W
G
S
Site 16
S185
S
P
D
R
L
W
G
S
R
L
T
F
N
H
D
Site 17
T188
R
L
W
G
S
R
L
T
F
N
H
D
G
S
S
Site 18
S194
L
T
F
N
H
D
G
S
S
R
Y
G
P
R
T
Site 19
S195
T
F
N
H
D
G
S
S
R
Y
G
P
R
T
Y
Site 20
T201
S
S
R
Y
G
P
R
T
Y
G
T
T
T
A
P
Site 21
Y202
S
R
Y
G
P
R
T
Y
G
T
T
T
A
P
R
Site 22
T205
G
P
R
T
Y
G
T
T
T
A
P
R
D
E
D
Site 23
S214
A
P
R
D
E
D
G
S
T
L
F
R
G
W
S
Site 24
T215
P
R
D
E
D
G
S
T
L
F
R
G
W
S
Q
Site 25
S221
S
T
L
F
R
G
W
S
Q
E
G
P
V
K
S
Site 26
S228
S
Q
E
G
P
V
K
S
P
A
E
C
R
E
E
Site 27
S237
A
E
C
R
E
E
H
S
K
T
P
E
E
R
S
Site 28
T239
C
R
E
E
H
S
K
T
P
E
E
R
S
L
P
Site 29
S244
S
K
T
P
E
E
R
S
L
P
S
D
L
A
F
Site 30
S247
P
E
E
R
S
L
P
S
D
L
A
F
N
G
D
Site 31
S268
S
E
L
P
A
D
I
S
K
P
W
I
P
S
S
Site 32
S274
I
S
K
P
W
I
P
S
S
P
A
P
S
S
E
Site 33
S275
S
K
P
W
I
P
S
S
P
A
P
S
S
E
N
Site 34
S279
I
P
S
S
P
A
P
S
S
E
N
G
G
P
A
Site 35
S280
P
S
S
P
A
P
S
S
E
N
G
G
P
A
S
Site 36
S287
S
E
N
G
G
P
A
S
P
G
L
P
A
E
A
Site 37
S295
P
G
L
P
A
E
A
S
G
S
G
P
G
S
P
Site 38
S297
L
P
A
E
A
S
G
S
G
P
G
S
P
H
L
Site 39
S301
A
S
G
S
G
P
G
S
P
H
L
H
P
P
D
Site 40
S310
H
L
H
P
P
D
K
S
S
P
C
H
S
Q
L
Site 41
S311
L
H
P
P
D
K
S
S
P
C
H
S
Q
L
L
Site 42
S315
D
K
S
S
P
C
H
S
Q
L
L
E
A
Q
S
Site 43
S322
S
Q
L
L
E
A
Q
S
P
E
A
S
Q
A
S
Site 44
S326
E
A
Q
S
P
E
A
S
Q
A
S
P
C
P
A
Site 45
S329
S
P
E
A
S
Q
A
S
P
C
P
A
V
T
P
Site 46
S348
A
A
L
P
D
E
G
S
R
H
T
P
S
P
G
Site 47
T351
P
D
E
G
S
R
H
T
P
S
P
G
L
P
A
Site 48
S353
E
G
S
R
H
T
P
S
P
G
L
P
A
E
G
Site 49
S368
A
P
E
A
P
R
P
S
S
P
P
P
E
V
L
Site 50
S369
P
E
A
P
R
P
S
S
P
P
P
E
V
L
E
Site 51
S379
P
E
V
L
E
P
H
S
L
D
Q
P
P
A
T
Site 52
T386
S
L
D
Q
P
P
A
T
S
P
R
P
L
I
E
Site 53
S387
L
D
Q
P
P
A
T
S
P
R
P
L
I
E
V
Site 54
T401
V
G
E
L
L
D
L
T
R
T
F
P
S
G
G
Site 55
T403
E
L
L
D
L
T
R
T
F
P
S
G
G
E
E
Site 56
T421
G
D
A
H
L
R
P
T
S
L
V
Q
R
R
F
Site 57
S422
D
A
H
L
R
P
T
S
L
V
Q
R
R
F
S
Site 58
S429
S
L
V
Q
R
R
F
S
E
G
V
L
Q
S
P
Site 59
S435
F
S
E
G
V
L
Q
S
P
S
Q
D
Q
E
K
Site 60
S437
E
G
V
L
Q
S
P
S
Q
D
Q
E
K
L
G
Site 61
S446
D
Q
E
K
L
G
G
S
L
A
A
L
P
Q
G
Site 62
S456
A
L
P
Q
G
Q
G
S
Q
L
A
L
D
R
P
Site 63
S468
D
R
P
F
G
A
E
S
N
W
S
L
S
Q
S
Site 64
S471
F
G
A
E
S
N
W
S
L
S
Q
S
F
E
W
Site 65
S473
A
E
S
N
W
S
L
S
Q
S
F
E
W
T
F
Site 66
S475
S
N
W
S
L
S
Q
S
F
E
W
T
F
P
T
Site 67
T479
L
S
Q
S
F
E
W
T
F
P
T
R
P
S
G
Site 68
T482
S
F
E
W
T
F
P
T
R
P
S
G
L
G
V
Site 69
S485
W
T
F
P
T
R
P
S
G
L
G
V
W
R
L
Site 70
S494
L
G
V
W
R
L
D
S
P
P
P
S
P
I
T
Site 71
S498
R
L
D
S
P
P
P
S
P
I
T
E
A
S
E
Site 72
T501
S
P
P
P
S
P
I
T
E
A
S
E
A
A
E
Site 73
S504
P
S
P
I
T
E
A
S
E
A
A
E
A
A
E
Site 74
S518
E
A
G
N
L
A
V
S
S
R
E
E
G
V
S
Site 75
S519
A
G
N
L
A
V
S
S
R
E
E
G
V
S
Q
Site 76
S525
S
S
R
E
E
G
V
S
Q
Q
G
Q
G
A
G
Site 77
S533
Q
Q
G
Q
G
A
G
S
A
P
S
G
S
G
S
Site 78
S536
Q
G
A
G
S
A
P
S
G
S
G
S
S
W
V
Site 79
S538
A
G
S
A
P
S
G
S
G
S
S
W
V
Q
G
Site 80
S540
S
A
P
S
G
S
G
S
S
W
V
Q
G
D
D
Site 81
S541
A
P
S
G
S
G
S
S
W
V
Q
G
D
D
P
Site 82
S549
W
V
Q
G
D
D
P
S
M
S
L
T
Q
K
G
Site 83
S551
Q
G
D
D
P
S
M
S
L
T
Q
K
G
D
G
Site 84
T553
D
D
P
S
M
S
L
T
Q
K
G
D
G
E
S
Site 85
S560
T
Q
K
G
D
G
E
S
Q
P
Q
F
P
A
V
Site 86
T574
V
P
L
E
P
L
P
T
T
E
G
T
P
G
L
Site 87
T578
P
L
P
T
T
E
G
T
P
G
L
P
L
Q
Q
Site 88
Y590
L
Q
Q
A
E
E
R
Y
E
S
Q
E
P
L
A
Site 89
S592
Q
A
E
E
R
Y
E
S
Q
E
P
L
A
G
Q
Site 90
S601
E
P
L
A
G
Q
E
S
P
L
P
L
A
T
R
Site 91
T607
E
S
P
L
P
L
A
T
R
E
A
A
L
P
I
Site 92
T652
P
V
E
E
E
A
V
T
L
A
R
A
E
T
T
Site 93
T658
V
T
L
A
R
A
E
T
T
Q
A
R
T
E
A
Site 94
T663
A
E
T
T
Q
A
R
T
E
A
Q
D
L
C
R
Site 95
S672
A
Q
D
L
C
R
A
S
P
E
P
P
G
P
E
Site 96
S680
P
E
P
P
G
P
E
S
S
S
R
W
L
D
D
Site 97
S681
E
P
P
G
P
E
S
S
S
R
W
L
D
D
L
Site 98
S682
P
P
G
P
E
S
S
S
R
W
L
D
D
L
L
Site 99
S691
W
L
D
D
L
L
A
S
P
P
P
S
G
G
G
Site 100
S695
L
L
A
S
P
P
P
S
G
G
G
A
R
R
G
Site 101
T710
A
G
A
E
L
K
D
T
Q
S
P
S
T
C
S
Site 102
S712
A
E
L
K
D
T
Q
S
P
S
T
C
S
E
G
Site 103
S714
L
K
D
T
Q
S
P
S
T
C
S
E
G
L
L
Site 104
T715
K
D
T
Q
S
P
S
T
C
S
E
G
L
L
G
Site 105
S717
T
Q
S
P
S
T
C
S
E
G
L
L
G
W
S
Site 106
S724
S
E
G
L
L
G
W
S
Q
K
D
L
Q
S
E
Site 107
S730
W
S
Q
K
D
L
Q
S
E
F
G
I
T
G
D
Site 108
T735
L
Q
S
E
F
G
I
T
G
D
P
Q
P
S
S
Site 109
S741
I
T
G
D
P
Q
P
S
S
F
S
P
S
S
W
Site 110
S742
T
G
D
P
Q
P
S
S
F
S
P
S
S
W
C
Site 111
S744
D
P
Q
P
S
S
F
S
P
S
S
W
C
Q
G
Site 112
S746
Q
P
S
S
F
S
P
S
S
W
C
Q
G
A
S
Site 113
S747
P
S
S
F
S
P
S
S
W
C
Q
G
A
S
Q
Site 114
S753
S
S
W
C
Q
G
A
S
Q
D
Y
G
L
G
G
Site 115
Y756
C
Q
G
A
S
Q
D
Y
G
L
G
G
A
S
P
Site 116
S762
D
Y
G
L
G
G
A
S
P
R
G
D
P
G
L
Site 117
T775
G
L
G
E
R
D
W
T
S
K
Y
G
Q
G
A
Site 118
S776
L
G
E
R
D
W
T
S
K
Y
G
Q
G
A
G
Site 119
Y778
E
R
D
W
T
S
K
Y
G
Q
G
A
G
E
G
Site 120
S786
G
Q
G
A
G
E
G
S
T
R
E
W
A
S
R
Site 121
S792
G
S
T
R
E
W
A
S
R
C
G
I
G
Q
E
Site 122
S804
G
Q
E
E
M
E
A
S
S
S
Q
D
Q
S
K
Site 123
S806
E
E
M
E
A
S
S
S
Q
D
Q
S
K
V
S
Site 124
S810
A
S
S
S
Q
D
Q
S
K
V
S
A
P
G
V
Site 125
S813
S
Q
D
Q
S
K
V
S
A
P
G
V
L
T
A
Site 126
T833
G
K
P
A
Q
L
G
T
Q
R
S
Q
E
A
D
Site 127
S836
A
Q
L
G
T
Q
R
S
Q
E
A
D
V
Q
D
Site 128
S851
W
E
F
R
K
R
D
S
Q
G
T
Y
S
S
R
Site 129
T854
R
K
R
D
S
Q
G
T
Y
S
S
R
D
A
E
Site 130
Y855
K
R
D
S
Q
G
T
Y
S
S
R
D
A
E
L
Site 131
S856
R
D
S
Q
G
T
Y
S
S
R
D
A
E
L
Q
Site 132
S857
D
S
Q
G
T
Y
S
S
R
D
A
E
L
Q
D
Site 133
S872
Q
E
F
G
K
R
D
S
L
G
T
Y
S
S
R
Site 134
T875
G
K
R
D
S
L
G
T
Y
S
S
R
D
V
S
Site 135
Y876
K
R
D
S
L
G
T
Y
S
S
R
D
V
S
L
Site 136
S877
R
D
S
L
G
T
Y
S
S
R
D
V
S
L
G
Site 137
S878
D
S
L
G
T
Y
S
S
R
D
V
S
L
G
D
Site 138
S882
T
Y
S
S
R
D
V
S
L
G
D
W
E
F
G
Site 139
S893
W
E
F
G
K
R
D
S
L
G
A
Y
A
S
Q
Site 140
Y897
K
R
D
S
L
G
A
Y
A
S
Q
D
A
N
E
Site 141
S899
D
S
L
G
A
Y
A
S
Q
D
A
N
E
Q
G
Site 142
Y918
K
R
D
H
H
G
R
Y
S
S
Q
D
A
D
E
Site 143
S919
R
D
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H
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R
Y
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Site 144
S920
D
H
H
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A
D
E
Q
D
Site 145
S936
E
F
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Y
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Site 146
T939
K
R
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G
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A
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Site 147
Y940
R
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Y
G
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A
E
P
Site 148
S942
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G
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A
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Q
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Site 149
Y961
K
S
A
W
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Y
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S
G
G
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S
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Site 150
S962
S
A
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Y
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G
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S
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Site 151
S963
A
W
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G
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Site 152
S966
R
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Y
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G
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A
Q
Site 153
S967
D
Y
S
S
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G
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Q
D
Site 154
S976
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L
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A
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Site 155
T979
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Q
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Site 156
S983
S
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Site 157
S984
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G
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E
A
Site 158
S987
R
P
L
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S
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E
E
A
Q
Q
Q
Site 159
S1004
E
F
E
K
K
I
P
S
V
E
D
S
L
G
E
Site 160
S1008
K
I
P
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E
D
S
L
G
E
G
S
R
D
Site 161
S1013
E
D
S
L
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E
G
S
R
D
A
G
R
P
G
Site 162
S1024
G
R
P
G
E
R
G
S
G
G
L
F
S
P
S
Site 163
S1029
R
G
S
G
G
L
F
S
P
S
T
A
H
V
P
Site 164
S1031
S
G
G
L
F
S
P
S
T
A
H
V
P
D
G
Site 165
T1032
G
G
L
F
S
P
S
T
A
H
V
P
D
G
A
Site 166
S1046
A
L
G
Q
R
D
Q
S
S
W
Q
N
S
D
A
Site 167
S1047
L
G
Q
R
D
Q
S
S
W
Q
N
S
D
A
S
Site 168
S1051
D
Q
S
S
W
Q
N
S
D
A
S
Q
E
V
G
Site 169
S1054
S
W
Q
N
S
D
A
S
Q
E
V
G
G
H
Q
Site 170
S1073
A
G
A
Q
G
P
G
S
A
D
L
E
D
G
E
Site 171
S1091
R
G
W
V
G
E
F
S
L
S
V
G
P
Q
R
Site 172
S1093
W
V
G
E
F
S
L
S
V
G
P
Q
R
E
A
Site 173
S1103
P
Q
R
E
A
A
F
S
P
G
Q
Q
D
W
S
Site 174
S1118
R
D
F
C
I
E
A
S
E
R
S
Y
Q
F
G
Site 175
Y1122
I
E
A
S
E
R
S
Y
Q
F
G
I
I
G
N
Site 176
S1133
I
I
G
N
D
R
V
S
G
A
G
F
S
P
S
Site 177
S1138
R
V
S
G
A
G
F
S
P
S
S
K
M
E
G
Site 178
S1140
S
G
A
G
F
S
P
S
S
K
M
E
G
G
H
Site 179
S1141
G
A
G
F
S
P
S
S
K
M
E
G
G
H
F
Site 180
T1154
H
F
V
P
P
G
K
T
T
A
G
S
V
D
W
Site 181
S1158
P
G
K
T
T
A
G
S
V
D
W
T
D
Q
L
Site 182
T1162
T
A
G
S
V
D
W
T
D
Q
L
G
L
R
N
Site 183
S1174
L
R
N
L
E
V
S
S
C
V
G
S
G
G
S
Site 184
S1178
E
V
S
S
C
V
G
S
G
G
S
S
E
A
R
Site 185
S1181
S
C
V
G
S
G
G
S
S
E
A
R
E
S
A
Site 186
S1182
C
V
G
S
G
G
S
S
E
A
R
E
S
A
V
Site 187
S1187
G
S
S
E
A
R
E
S
A
V
G
Q
M
G
W
Site 188
S1195
A
V
G
Q
M
G
W
S
G
G
L
S
L
R
D
Site 189
S1199
M
G
W
S
G
G
L
S
L
R
D
M
N
L
T
Site 190
T1206
S
L
R
D
M
N
L
T
G
C
L
E
S
G
G
Site 191
S1214
G
C
L
E
S
G
G
S
E
E
P
G
G
I
G
Site 192
T1228
G
V
G
E
K
D
W
T
S
D
V
N
V
K
S
Site 193
S1229
V
G
E
K
D
W
T
S
D
V
N
V
K
S
K
Site 194
S1248
V
G
E
G
G
G
H
S
Q
A
R
E
S
G
V
Site 195
S1253
G
H
S
Q
A
R
E
S
G
V
G
Q
T
D
W
Site 196
S1261
G
V
G
Q
T
D
W
S
G
V
E
A
G
E
F
Site 197
S1271
E
A
G
E
F
L
K
S
R
E
R
G
V
G
Q
Site 198
T1282
G
V
G
Q
A
D
W
T
P
D
L
G
L
R
N
Site 199
S1297
M
A
P
G
A
V
C
S
P
G
E
S
K
E
L
Site 200
S1301
A
V
C
S
P
G
E
S
K
E
L
G
V
G
Q
Site 201
T1323
G
L
R
D
L
E
V
T
C
D
P
D
S
G
G
Site 202
S1328
E
V
T
C
D
P
D
S
G
G
S
Q
G
L
R
Site 203
S1331
C
D
P
D
S
G
G
S
Q
G
L
R
G
C
G
Site 204
T1345
G
V
G
Q
M
D
W
T
Q
D
L
A
P
Q
N
Site 205
S1360
V
E
L
F
G
A
P
S
E
A
R
E
H
G
V
Site 206
S1371
E
H
G
V
G
G
V
S
Q
C
P
E
P
G
L
Site 207
S1383
P
G
L
R
H
N
G
S
L
S
P
G
L
E
A
Site 208
S1385
L
R
H
N
G
S
L
S
P
G
L
E
A
R
D
Site 209
S1405
E
L
G
V
G
E
T
S
G
P
E
T
Q
G
E
Site 210
T1409
G
E
T
S
G
P
E
T
Q
G
E
D
Y
S
S
Site 211
Y1414
P
E
T
Q
G
E
D
Y
S
S
S
S
L
E
P
Site 212
S1415
E
T
Q
G
E
D
Y
S
S
S
S
L
E
P
H
Site 213
S1416
T
Q
G
E
D
Y
S
S
S
S
L
E
P
H
P
Site 214
S1417
Q
G
E
D
Y
S
S
S
S
L
E
P
H
P
A
Site 215
S1418
G
E
D
Y
S
S
S
S
L
E
P
H
P
A
D
Site 216
S1435
M
E
T
G
E
A
L
S
F
G
A
S
P
G
R
Site 217
S1439
E
A
L
S
F
G
A
S
P
G
R
C
P
A
R
Site 218
S1450
C
P
A
R
P
P
P
S
G
S
Q
G
L
L
E
Site 219
S1452
A
R
P
P
P
S
G
S
Q
G
L
L
E
E
M
Site 220
S1465
E
M
L
A
A
S
S
S
K
A
V
A
R
R
E
Site 221
S1473
K
A
V
A
R
R
E
S
A
A
S
G
L
G
G
Site 222
S1476
A
R
R
E
S
A
A
S
G
L
G
G
L
L
E
Site 223
S1503
V
L
E
P
G
R
D
S
P
P
S
W
R
P
Q
Site 224
S1506
P
G
R
D
S
P
P
S
W
R
P
Q
P
D
G
Site 225
S1516
P
Q
P
D
G
E
A
S
Q
T
E
D
V
D
G
Site 226
T1518
P
D
G
E
A
S
Q
T
E
D
V
D
G
T
W
Site 227
T1524
Q
T
E
D
V
D
G
T
W
G
S
S
A
A
R
Site 228
S1528
V
D
G
T
W
G
S
S
A
A
R
W
S
D
Q
Site 229
S1533
G
S
S
A
A
R
W
S
D
Q
G
P
A
Q
T
Site 230
T1540
S
D
Q
G
P
A
Q
T
S
R
R
P
S
Q
G
Site 231
S1541
D
Q
G
P
A
Q
T
S
R
R
P
S
Q
G
P
Site 232
S1545
A
Q
T
S
R
R
P
S
Q
G
P
P
A
R
S
Site 233
S1552
S
Q
G
P
P
A
R
S
P
S
Q
D
F
S
F
Site 234
S1554
G
P
P
A
R
S
P
S
Q
D
F
S
F
I
E
Site 235
S1558
R
S
P
S
Q
D
F
S
F
I
E
D
T
E
I
Site 236
T1563
D
F
S
F
I
E
D
T
E
I
L
D
S
A
M
Site 237
S1568
E
D
T
E
I
L
D
S
A
M
Y
R
S
R
A
Site 238
Y1571
E
I
L
D
S
A
M
Y
R
S
R
A
N
L
G
Site 239
S1597
P
G
G
T
L
G
L
S
E
A
A
D
S
D
A
Site 240
S1602
G
L
S
E
A
A
D
S
D
A
H
L
F
Q
D
Site 241
S1610
D
A
H
L
F
Q
D
S
T
E
P
R
A
S
R
Site 242
T1611
A
H
L
F
Q
D
S
T
E
P
R
A
S
R
V
Site 243
S1616
D
S
T
E
P
R
A
S
R
V
P
S
S
D
E
Site 244
S1620
P
R
A
S
R
V
P
S
S
D
E
E
V
V
E
Site 245
S1621
R
A
S
R
V
P
S
S
D
E
E
V
V
E
E
Site 246
S1631
E
V
V
E
E
P
Q
S
R
R
T
R
M
S
L
Site 247
T1634
E
E
P
Q
S
R
R
T
R
M
S
L
G
T
K
Site 248
S1637
Q
S
R
R
T
R
M
S
L
G
T
K
G
L
K
Site 249
S1652
V
N
L
F
P
G
L
S
P
S
A
L
K
A
K
Site 250
S1654
L
F
P
G
L
S
P
S
A
L
K
A
K
L
R
Site 251
S1666
K
L
R
P
R
N
R
S
A
E
E
G
E
L
A
Site 252
S1675
E
E
G
E
L
A
E
S
K
S
S
Q
K
E
S
Site 253
S1677
G
E
L
A
E
S
K
S
S
Q
K
E
S
A
V
Site 254
S1678
E
L
A
E
S
K
S
S
Q
K
E
S
A
V
Q
Site 255
S1682
S
K
S
S
Q
K
E
S
A
V
Q
R
S
K
S
Site 256
S1689
S
A
V
Q
R
S
K
S
C
K
V
P
G
L
G
Site 257
T1700
P
G
L
G
K
P
L
T
L
P
P
K
P
E
K
Site 258
S1708
L
P
P
K
P
E
K
S
S
G
S
E
G
S
S
Site 259
S1709
P
P
K
P
E
K
S
S
G
S
E
G
S
S
P
Site 260
S1711
K
P
E
K
S
S
G
S
E
G
S
S
P
N
W
Site 261
S1714
K
S
S
G
S
E
G
S
S
P
N
W
L
Q
A
Site 262
S1715
S
S
G
S
E
G
S
S
P
N
W
L
Q
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation