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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF518B
Full Name:
Zinc finger protein 518B
Alias:
Type:
Mass (Da):
119531
Number AA:
1074
UniProt ID:
Q9C0D4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
K
D
I
G
Q
Q
L
Y
T
T
H
L
N
G
G
Site 2
T11
I
G
Q
Q
L
Y
T
T
H
L
N
G
G
H
N
Site 3
S19
H
L
N
G
G
H
N
S
L
T
M
S
P
K
Q
Site 4
T21
N
G
G
H
N
S
L
T
M
S
P
K
Q
P
D
Site 5
S23
G
H
N
S
L
T
M
S
P
K
Q
P
D
A
N
Site 6
T42
P
N
R
Q
E
A
Q
T
L
L
Y
Q
G
S
E
Site 7
S48
Q
T
L
L
Y
Q
G
S
E
A
E
A
A
M
M
Site 8
S65
A
T
C
A
K
C
K
S
V
H
K
I
S
L
Q
Site 9
S70
C
K
S
V
H
K
I
S
L
Q
D
L
Q
K
G
Site 10
S102
P
P
N
F
H
F
V
S
N
N
S
S
A
T
H
Site 11
S106
H
F
V
S
N
N
S
S
A
T
H
V
G
N
K
Site 12
T114
A
T
H
V
G
N
K
T
E
N
F
S
S
S
V
Site 13
S118
G
N
K
T
E
N
F
S
S
S
V
N
S
K
F
Site 14
S119
N
K
T
E
N
F
S
S
S
V
N
S
K
F
K
Site 15
S120
K
T
E
N
F
S
S
S
V
N
S
K
F
K
V
Site 16
S123
N
F
S
S
S
V
N
S
K
F
K
V
R
N
F
Site 17
Y135
R
N
F
K
P
G
K
Y
Y
C
D
K
C
R
F
Site 18
T144
C
D
K
C
R
F
S
T
K
D
P
L
Q
Y
K
Site 19
Y169
F
I
C
S
H
C
S
Y
I
S
Y
T
K
G
E
Site 20
Y172
S
H
C
S
Y
I
S
Y
T
K
G
E
F
Q
R
Site 21
Y194
I
F
P
Y
Q
C
E
Y
C
D
Y
G
A
I
R
Site 22
Y197
Y
Q
C
E
Y
C
D
Y
G
A
I
R
N
D
Y
Site 23
Y204
Y
G
A
I
R
N
D
Y
I
V
K
H
T
K
R
Site 24
T233
A
K
L
E
P
K
R
T
G
T
S
K
Q
N
P
Site 25
T235
L
E
P
K
R
T
G
T
S
K
Q
N
P
E
L
Site 26
T250
L
K
A
S
N
P
R
T
T
F
Q
N
K
W
S
Site 27
T251
K
A
S
N
P
R
T
T
F
Q
N
K
W
S
D
Site 28
S257
T
T
F
Q
N
K
W
S
D
Q
L
S
G
F
S
Site 29
S261
N
K
W
S
D
Q
L
S
G
F
S
L
H
A
N
Site 30
Y284
L
L
P
E
P
K
E
Y
Q
K
D
V
V
C
I
Site 31
S298
I
P
N
K
M
T
L
S
E
P
N
E
V
N
L
Site 32
S317
N
V
E
V
E
V
L
S
P
A
K
E
P
V
Q
Site 33
S382
G
R
D
N
G
G
N
S
E
R
M
V
K
E
K
Site 34
S399
N
E
Q
E
K
V
L
S
A
E
K
T
K
S
L
Site 35
T403
K
V
L
S
A
E
K
T
K
S
L
T
V
D
G
Site 36
S405
L
S
A
E
K
T
K
S
L
T
V
D
G
N
V
Site 37
T407
A
E
K
T
K
S
L
T
V
D
G
N
V
G
K
Site 38
S420
G
K
L
V
G
I
D
S
F
Q
P
S
V
Q
K
Site 39
S424
G
I
D
S
F
Q
P
S
V
Q
K
Q
L
K
N
Site 40
Y438
N
V
K
W
V
R
S
Y
D
F
I
M
P
N
S
Site 41
S446
D
F
I
M
P
N
S
S
V
H
N
N
G
K
S
Site 42
S453
S
V
H
N
N
G
K
S
F
I
N
S
E
T
I
Site 43
S457
N
G
K
S
F
I
N
S
E
T
I
E
D
F
Q
Site 44
Y470
F
Q
K
K
N
N
L
Y
P
H
R
T
A
F
P
Site 45
T474
N
N
L
Y
P
H
R
T
A
F
P
S
V
A
L
Site 46
S478
P
H
R
T
A
F
P
S
V
A
L
K
G
H
S
Site 47
S497
F
K
N
S
V
L
R
S
L
G
A
A
S
N
P
Site 48
S516
A
A
V
C
F
A
E
S
G
R
N
L
H
S
S
Site 49
S522
E
S
G
R
N
L
H
S
S
S
Q
Q
L
L
P
Site 50
S523
S
G
R
N
L
H
S
S
S
Q
Q
L
L
P
F
Site 51
S524
G
R
N
L
H
S
S
S
Q
Q
L
L
P
F
A
Site 52
T536
P
F
A
A
S
P
A
T
C
S
F
S
G
E
K
Site 53
S538
A
A
S
P
A
T
C
S
F
S
G
E
K
G
L
Site 54
S540
S
P
A
T
C
S
F
S
G
E
K
G
L
L
P
Site 55
S549
E
K
G
L
L
P
V
S
E
N
D
L
E
S
T
Site 56
S555
V
S
E
N
D
L
E
S
T
S
K
V
N
I
P
Site 57
S567
N
I
P
V
K
V
V
S
S
N
R
K
Q
E
D
Site 58
S568
I
P
V
K
V
V
S
S
N
R
K
Q
E
D
N
Site 59
T577
R
K
Q
E
D
N
Q
T
E
E
H
K
A
V
S
Site 60
S591
S
T
V
G
Q
I
S
S
Q
H
K
S
E
Y
L
Site 61
Y597
S
S
Q
H
K
S
E
Y
L
H
I
N
I
T
G
Site 62
T603
E
Y
L
H
I
N
I
T
G
E
D
R
S
Q
Q
Site 63
S608
N
I
T
G
E
D
R
S
Q
Q
P
G
D
K
P
Site 64
S621
K
P
L
E
L
K
N
S
E
R
T
N
N
T
N
Site 65
S641
S
S
V
F
S
L
S
S
G
S
E
N
V
P
E
Site 66
S654
P
E
G
I
K
W
N
S
S
T
S
K
I
K
S
Site 67
S655
E
G
I
K
W
N
S
S
T
S
K
I
K
S
I
Site 68
S661
S
S
T
S
K
I
K
S
I
E
L
L
R
R
K
Site 69
S675
K
I
A
Q
L
I
E
S
C
G
K
P
S
S
L
Site 70
S680
I
E
S
C
G
K
P
S
S
L
A
S
N
S
A
Site 71
S681
E
S
C
G
K
P
S
S
L
A
S
N
S
A
H
Site 72
S684
G
K
P
S
S
L
A
S
N
S
A
H
R
R
S
Site 73
S686
P
S
S
L
A
S
N
S
A
H
R
R
S
V
G
Site 74
S691
S
N
S
A
H
R
R
S
V
G
Q
A
S
K
G
Site 75
S696
R
R
S
V
G
Q
A
S
K
G
T
S
K
A
T
Site 76
S700
G
Q
A
S
K
G
T
S
K
A
T
S
E
G
I
Site 77
S704
K
G
T
S
K
A
T
S
E
G
I
Q
E
I
N
Site 78
T723
G
L
G
H
S
T
G
T
L
Q
K
P
P
N
D
Site 79
T740
I
T
G
N
R
Q
L
T
H
Q
Q
I
Y
P
H
Site 80
Y745
Q
L
T
H
Q
Q
I
Y
P
H
F
A
D
G
S
Site 81
S752
Y
P
H
F
A
D
G
S
N
R
K
T
K
S
R
Site 82
T756
A
D
G
S
N
R
K
T
K
S
R
V
A
R
K
Site 83
S758
G
S
N
R
K
T
K
S
R
V
A
R
K
A
H
Site 84
S799
A
T
C
E
A
P
V
S
I
P
C
S
E
R
Q
Site 85
S803
A
P
V
S
I
P
C
S
E
R
Q
L
I
K
P
Site 86
S821
C
P
V
R
Q
A
D
S
D
L
Q
P
L
R
S
Site 87
S828
S
D
L
Q
P
L
R
S
E
R
G
P
I
D
M
Site 88
S836
E
R
G
P
I
D
M
S
P
N
I
E
T
P
L
Site 89
T841
D
M
S
P
N
I
E
T
P
L
R
P
K
L
R
Site 90
S851
R
P
K
L
R
K
E
S
A
V
C
S
T
I
H
Site 91
S855
R
K
E
S
A
V
C
S
T
I
H
R
K
T
G
Site 92
T861
C
S
T
I
H
R
K
T
G
L
L
Y
G
Q
Q
Site 93
Y865
H
R
K
T
G
L
L
Y
G
Q
Q
G
S
S
E
Site 94
S881
N
K
Q
G
R
L
L
S
R
S
L
S
I
S
R
Site 95
S883
Q
G
R
L
L
S
R
S
L
S
I
S
R
N
K
Site 96
S885
R
L
L
S
R
S
L
S
I
S
R
N
K
T
K
Site 97
S887
L
S
R
S
L
S
I
S
R
N
K
T
K
Q
V
Site 98
T891
L
S
I
S
R
N
K
T
K
Q
V
H
L
S
R
Site 99
S897
K
T
K
Q
V
H
L
S
R
K
K
N
K
I
Q
Site 100
S915
S
R
C
L
K
D
P
S
I
F
Q
V
A
R
Q
Site 101
S953
L
N
H
P
D
V
D
S
P
E
V
T
N
V
M
Site 102
T957
D
V
D
S
P
E
V
T
N
V
M
K
V
I
N
Site 103
T993
R
R
H
H
V
R
L
T
Y
Q
N
A
E
E
A
Site 104
Y994
R
H
H
V
R
L
T
Y
Q
N
A
E
E
A
S
Site 105
Y1021
K
K
V
H
K
N
N
Y
Q
V
V
D
S
L
P
Site 106
S1026
N
N
Y
Q
V
V
D
S
L
P
D
D
S
S
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation