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Updated November 2019
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Protein Info
Short Name:
FAM190A
Full Name:
Protein FAM190A
Alias:
Type:
Mass (Da):
99510
Number AA:
900
UniProt ID:
Q9C0I3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
D
S
G
S
R
R
S
T
L
V
S
Site 2
S9
G
D
S
G
S
R
R
S
T
L
V
S
R
L
P
Site 3
T10
D
S
G
S
R
R
S
T
L
V
S
R
L
P
I
Site 4
S13
S
R
R
S
T
L
V
S
R
L
P
I
F
R
R
Site 5
S21
R
L
P
I
F
R
R
S
I
N
R
R
H
D
S
Site 6
S28
S
I
N
R
R
H
D
S
L
P
S
S
P
S
S
Site 7
S31
R
R
H
D
S
L
P
S
S
P
S
S
S
N
T
Site 8
S32
R
H
D
S
L
P
S
S
P
S
S
S
N
T
V
Site 9
S34
D
S
L
P
S
S
P
S
S
S
N
T
V
G
V
Site 10
S35
S
L
P
S
S
P
S
S
S
N
T
V
G
V
H
Site 11
S36
L
P
S
S
P
S
S
S
N
T
V
G
V
H
S
Site 12
T38
S
S
P
S
S
S
N
T
V
G
V
H
S
S
S
Site 13
S43
S
N
T
V
G
V
H
S
S
S
P
S
S
T
N
Site 14
S44
N
T
V
G
V
H
S
S
S
P
S
S
T
N
S
Site 15
S45
T
V
G
V
H
S
S
S
P
S
S
T
N
S
S
Site 16
S47
G
V
H
S
S
S
P
S
S
T
N
S
S
S
G
Site 17
S48
V
H
S
S
S
P
S
S
T
N
S
S
S
G
S
Site 18
T49
H
S
S
S
P
S
S
T
N
S
S
S
G
S
T
Site 19
S51
S
S
P
S
S
T
N
S
S
S
G
S
T
G
K
Site 20
S52
S
P
S
S
T
N
S
S
S
G
S
T
G
K
R
Site 21
S53
P
S
S
T
N
S
S
S
G
S
T
G
K
R
R
Site 22
S55
S
T
N
S
S
S
G
S
T
G
K
R
R
S
I
Site 23
T56
T
N
S
S
S
G
S
T
G
K
R
R
S
I
F
Site 24
S61
G
S
T
G
K
R
R
S
I
F
R
T
P
S
I
Site 25
T65
K
R
R
S
I
F
R
T
P
S
I
S
F
H
H
Site 26
S67
R
S
I
F
R
T
P
S
I
S
F
H
H
K
K
Site 27
S69
I
F
R
T
P
S
I
S
F
H
H
K
K
G
S
Site 28
S76
S
F
H
H
K
K
G
S
E
P
K
Q
E
P
T
Site 29
S88
E
P
T
N
Q
N
L
S
I
S
N
G
A
Q
P
Site 30
S90
T
N
Q
N
L
S
I
S
N
G
A
Q
P
G
H
Site 31
S98
N
G
A
Q
P
G
H
S
N
M
Q
K
L
S
L
Site 32
S104
H
S
N
M
Q
K
L
S
L
E
E
H
I
K
T
Site 33
T111
S
L
E
E
H
I
K
T
R
G
R
H
S
V
G
Site 34
S116
I
K
T
R
G
R
H
S
V
G
F
S
S
S
R
Site 35
S120
G
R
H
S
V
G
F
S
S
S
R
N
K
K
I
Site 36
S121
R
H
S
V
G
F
S
S
S
R
N
K
K
I
T
Site 37
S122
H
S
V
G
F
S
S
S
R
N
K
K
I
T
R
Site 38
T128
S
S
R
N
K
K
I
T
R
S
L
T
E
D
F
Site 39
S130
R
N
K
K
I
T
R
S
L
T
E
D
F
E
R
Site 40
T132
K
K
I
T
R
S
L
T
E
D
F
E
R
E
K
Site 41
S142
F
E
R
E
K
E
H
S
T
N
K
N
V
F
I
Site 42
S153
N
V
F
I
N
C
L
S
S
G
K
S
E
G
D
Site 43
S154
V
F
I
N
C
L
S
S
G
K
S
E
G
D
D
Site 44
S157
N
C
L
S
S
G
K
S
E
G
D
D
S
G
F
Site 45
S162
G
K
S
E
G
D
D
S
G
F
T
E
D
Q
T
Site 46
T165
E
G
D
D
S
G
F
T
E
D
Q
T
R
R
S
Site 47
T169
S
G
F
T
E
D
Q
T
R
R
S
V
K
Q
S
Site 48
S172
T
E
D
Q
T
R
R
S
V
K
Q
S
T
R
K
Site 49
S176
T
R
R
S
V
K
Q
S
T
R
K
L
L
P
K
Site 50
S184
T
R
K
L
L
P
K
S
F
S
S
H
Y
K
F
Site 51
S186
K
L
L
P
K
S
F
S
S
H
Y
K
F
S
K
Site 52
S187
L
L
P
K
S
F
S
S
H
Y
K
F
S
K
P
Site 53
Y189
P
K
S
F
S
S
H
Y
K
F
S
K
P
V
L
Site 54
S192
F
S
S
H
Y
K
F
S
K
P
V
L
Q
S
Q
Site 55
S202
V
L
Q
S
Q
S
I
S
L
V
Q
Q
S
E
F
Site 56
S210
L
V
Q
Q
S
E
F
S
L
E
V
T
Q
Y
Q
Site 57
T214
S
E
F
S
L
E
V
T
Q
Y
Q
E
R
E
P
Site 58
Y216
F
S
L
E
V
T
Q
Y
Q
E
R
E
P
V
L
Site 59
S231
V
R
A
S
P
S
C
S
V
D
V
T
E
R
A
Site 60
T235
P
S
C
S
V
D
V
T
E
R
A
G
S
S
L
Site 61
S240
D
V
T
E
R
A
G
S
S
L
Q
S
P
L
L
Site 62
S241
V
T
E
R
A
G
S
S
L
Q
S
P
L
L
S
Site 63
S244
R
A
G
S
S
L
Q
S
P
L
L
S
A
D
L
Site 64
S248
S
L
Q
S
P
L
L
S
A
D
L
T
T
A
Q
Site 65
T252
P
L
L
S
A
D
L
T
T
A
Q
T
P
S
E
Site 66
T264
P
S
E
F
L
A
L
T
E
D
S
V
S
E
M
Site 67
S269
A
L
T
E
D
S
V
S
E
M
D
A
F
S
K
Site 68
S275
V
S
E
M
D
A
F
S
K
S
G
S
M
A
S
Site 69
S277
E
M
D
A
F
S
K
S
G
S
M
A
S
H
C
Site 70
S279
D
A
F
S
K
S
G
S
M
A
S
H
C
D
N
Site 71
S282
S
K
S
G
S
M
A
S
H
C
D
N
F
G
H
Site 72
S292
D
N
F
G
H
N
D
S
T
S
Q
M
S
L
N
Site 73
T293
N
F
G
H
N
D
S
T
S
Q
M
S
L
N
S
Site 74
S294
F
G
H
N
D
S
T
S
Q
M
S
L
N
S
A
Site 75
S297
N
D
S
T
S
Q
M
S
L
N
S
A
A
V
T
Site 76
T304
S
L
N
S
A
A
V
T
K
T
T
T
E
L
T
Site 77
S320
T
V
P
C
A
I
M
S
P
G
K
Y
R
L
E
Site 78
Y324
A
I
M
S
P
G
K
Y
R
L
E
G
Q
C
S
Site 79
S331
Y
R
L
E
G
Q
C
S
T
E
S
N
S
L
P
Site 80
T332
R
L
E
G
Q
C
S
T
E
S
N
S
L
P
E
Site 81
S334
E
G
Q
C
S
T
E
S
N
S
L
P
E
T
S
Site 82
S336
Q
C
S
T
E
S
N
S
L
P
E
T
S
A
A
Site 83
T340
E
S
N
S
L
P
E
T
S
A
A
N
Q
K
E
Site 84
T358
Q
I
A
E
L
P
A
T
S
V
S
H
S
E
S
Site 85
S359
I
A
E
L
P
A
T
S
V
S
H
S
E
S
N
Site 86
S361
E
L
P
A
T
S
V
S
H
S
E
S
N
L
P
Site 87
S363
P
A
T
S
V
S
H
S
E
S
N
L
P
A
D
Site 88
S365
T
S
V
S
H
S
E
S
N
L
P
A
D
S
E
Site 89
S371
E
S
N
L
P
A
D
S
E
R
E
E
N
I
G
Site 90
T388
N
G
E
T
M
L
G
T
N
S
P
R
K
L
G
Site 91
S390
E
T
M
L
G
T
N
S
P
R
K
L
G
F
Y
Site 92
Y397
S
P
R
K
L
G
F
Y
E
Q
H
K
A
I
A
Site 93
S414
V
K
G
I
H
P
I
S
D
S
K
I
I
P
T
Site 94
S416
G
I
H
P
I
S
D
S
K
I
I
P
T
S
G
Site 95
S446
P
A
K
V
L
A
S
S
L
S
P
F
R
E
G
Site 96
S448
K
V
L
A
S
S
L
S
P
F
R
E
G
R
F
Site 97
S462
F
I
E
R
R
L
R
S
S
S
E
G
T
A
G
Site 98
S463
I
E
R
R
L
R
S
S
S
E
G
T
A
G
S
Site 99
S464
E
R
R
L
R
S
S
S
E
G
T
A
G
S
S
Site 100
T467
L
R
S
S
S
E
G
T
A
G
S
S
R
M
I
Site 101
S470
S
S
E
G
T
A
G
S
S
R
M
I
L
K
P
Site 102
S487
G
N
I
E
E
V
N
S
L
R
K
Q
R
A
G
Site 103
S495
L
R
K
Q
R
A
G
S
S
S
S
K
M
N
S
Site 104
S496
R
K
Q
R
A
G
S
S
S
S
K
M
N
S
L
Site 105
S497
K
Q
R
A
G
S
S
S
S
K
M
N
S
L
D
Site 106
S498
Q
R
A
G
S
S
S
S
K
M
N
S
L
D
V
Site 107
S502
S
S
S
S
K
M
N
S
L
D
V
L
N
N
L
Site 108
S530
L
E
F
L
E
E
Q
S
L
H
P
S
V
C
R
Site 109
S534
E
E
Q
S
L
H
P
S
V
C
R
E
D
S
Y
Site 110
S540
P
S
V
C
R
E
D
S
Y
H
S
V
V
S
C
Site 111
Y541
S
V
C
R
E
D
S
Y
H
S
V
V
S
C
A
Site 112
S543
C
R
E
D
S
Y
H
S
V
V
S
C
A
A
V
Site 113
S578
E
P
S
K
Q
N
L
S
L
K
L
T
K
D
V
Site 114
T582
Q
N
L
S
L
K
L
T
K
D
V
D
Q
E
A
Site 115
S592
V
D
Q
E
A
R
C
S
H
I
S
R
M
P
N
Site 116
S595
E
A
R
C
S
H
I
S
R
M
P
N
S
P
S
Site 117
S600
H
I
S
R
M
P
N
S
P
S
A
D
W
P
L
Site 118
S602
S
R
M
P
N
S
P
S
A
D
W
P
L
Q
G
Site 119
S618
E
E
N
G
G
I
D
S
L
P
F
R
L
M
L
Site 120
T633
Q
D
C
T
A
V
K
T
L
L
L
K
M
K
R
Site 121
S645
M
K
R
V
L
Q
E
S
A
D
M
S
P
A
S
Site 122
S649
L
Q
E
S
A
D
M
S
P
A
S
S
T
T
S
Site 123
S652
S
A
D
M
S
P
A
S
S
T
T
S
L
P
V
Site 124
S653
A
D
M
S
P
A
S
S
T
T
S
L
P
V
S
Site 125
S656
S
P
A
S
S
T
T
S
L
P
V
S
P
L
T
Site 126
S660
S
T
T
S
L
P
V
S
P
L
T
E
E
P
V
Site 127
T663
S
L
P
V
S
P
L
T
E
E
P
V
P
F
K
Site 128
S678
D
I
M
K
D
E
C
S
M
L
K
L
Q
L
K
Site 129
S710
H
L
Q
K
A
F
A
S
R
V
D
K
S
T
Q
Site 130
S715
F
A
S
R
V
D
K
S
T
Q
T
E
L
L
C
Site 131
T716
A
S
R
V
D
K
S
T
Q
T
E
L
L
C
Y
Site 132
Y723
T
Q
T
E
L
L
C
Y
D
G
L
N
L
K
R
Site 133
T733
L
N
L
K
R
L
E
T
V
Q
G
G
R
E
A
Site 134
T741
V
Q
G
G
R
E
A
T
Y
R
N
R
I
V
S
Site 135
Y742
Q
G
G
R
E
A
T
Y
R
N
R
I
V
S
Q
Site 136
S748
T
Y
R
N
R
I
V
S
Q
N
L
S
T
R
D
Site 137
S752
R
I
V
S
Q
N
L
S
T
R
D
R
K
A
I
Site 138
T761
R
D
R
K
A
I
H
T
P
T
E
D
R
F
R
Site 139
T763
R
K
A
I
H
T
P
T
E
D
R
F
R
Y
S
Site 140
Y769
P
T
E
D
R
F
R
Y
S
A
A
D
Q
T
S
Site 141
S770
T
E
D
R
F
R
Y
S
A
A
D
Q
T
S
P
Site 142
T775
R
Y
S
A
A
D
Q
T
S
P
Y
K
N
K
T
Site 143
S776
Y
S
A
A
D
Q
T
S
P
Y
K
N
K
T
C
Site 144
T782
T
S
P
Y
K
N
K
T
C
Q
L
P
S
L
C
Site 145
S791
Q
L
P
S
L
C
L
S
N
F
L
K
D
K
E
Site 146
T809
V
I
K
H
S
R
G
T
Y
E
T
L
T
S
D
Site 147
Y810
I
K
H
S
R
G
T
Y
E
T
L
T
S
D
V
Site 148
T812
H
S
R
G
T
Y
E
T
L
T
S
D
V
T
Q
Site 149
T814
R
G
T
Y
E
T
L
T
S
D
V
T
Q
N
L
Site 150
S815
G
T
Y
E
T
L
T
S
D
V
T
Q
N
L
R
Site 151
T818
E
T
L
T
S
D
V
T
Q
N
L
R
A
T
V
Site 152
T824
V
T
Q
N
L
R
A
T
V
G
Q
S
S
L
K
Site 153
S829
R
A
T
V
G
Q
S
S
L
K
P
T
A
K
T
Site 154
T833
G
Q
S
S
L
K
P
T
A
K
T
E
G
L
S
Site 155
T836
S
L
K
P
T
A
K
T
E
G
L
S
T
F
L
Site 156
T841
A
K
T
E
G
L
S
T
F
L
E
K
P
K
D
Site 157
S857
V
A
T
A
R
Q
H
S
T
F
T
G
R
F
G
Site 158
T858
A
T
A
R
Q
H
S
T
F
T
G
R
F
G
Q
Site 159
S872
Q
P
P
R
G
P
I
S
L
H
M
Y
S
R
K
Site 160
Y876
G
P
I
S
L
H
M
Y
S
R
K
N
V
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation