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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC27
Full Name:
Leucine-rich repeat-containing protein 27
Alias:
Type:
Mass (Da):
60089
Number AA:
530
UniProt ID:
Q9C0I9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
G
S
S
S
Y
E
V
P
S
V
A
Site 2
Y7
_
M
E
G
S
S
S
Y
E
V
P
S
V
A
A
Site 3
S11
S
S
S
Y
E
V
P
S
V
A
A
A
D
L
E
Site 4
S26
E
G
A
G
Q
T
R
S
L
P
A
T
P
S
K
Site 5
T30
Q
T
R
S
L
P
A
T
P
S
K
D
V
H
K
Site 6
S32
R
S
L
P
A
T
P
S
K
D
V
H
K
G
V
Site 7
S55
P
I
L
D
L
S
E
S
G
L
C
R
L
E
E
Site 8
S68
E
E
V
F
R
I
P
S
L
Q
Q
L
H
L
Q
Site 9
Y100
L
T
W
L
D
L
R
Y
N
R
I
K
A
L
P
Site 10
T118
G
A
H
Q
H
L
K
T
L
L
L
E
R
N
P
Site 11
S176
R
M
W
A
V
E
H
S
L
P
R
N
P
T
S
Site 12
T182
H
S
L
P
R
N
P
T
S
Q
E
A
P
P
V
Site 13
S183
S
L
P
R
N
P
T
S
Q
E
A
P
P
V
R
Site 14
T193
A
P
P
V
R
E
M
T
L
R
D
L
P
S
P
Site 15
S199
M
T
L
R
D
L
P
S
P
G
L
E
L
S
G
Site 16
S205
P
S
P
G
L
E
L
S
G
D
H
A
S
N
Q
Site 17
S210
E
L
S
G
D
H
A
S
N
Q
G
A
V
N
A
Site 18
S230
A
V
M
K
E
K
A
S
F
L
P
P
V
E
K
Site 19
S241
P
V
E
K
P
D
L
S
E
L
R
K
S
A
D
Site 20
S246
D
L
S
E
L
R
K
S
A
D
S
S
E
N
W
Site 21
S249
E
L
R
K
S
A
D
S
S
E
N
W
P
S
E
Site 22
S250
L
R
K
S
A
D
S
S
E
N
W
P
S
E
E
Site 23
S255
D
S
S
E
N
W
P
S
E
E
E
I
R
R
F
Site 24
T312
R
H
V
F
R
R
K
T
A
S
S
R
S
I
L
Site 25
S314
V
F
R
R
K
T
A
S
S
R
S
I
L
P
D
Site 26
S315
F
R
R
K
T
A
S
S
R
S
I
L
P
D
L
Site 27
Y326
L
P
D
L
L
S
P
Y
Q
M
A
I
R
A
K
Site 28
S381
R
K
R
K
E
E
L
S
K
L
L
P
P
R
R
Site 29
S389
K
L
L
P
P
R
R
S
M
V
A
S
K
I
P
Site 30
S393
P
R
R
S
M
V
A
S
K
I
P
S
A
T
D
Site 31
S418
P
P
G
K
M
K
P
S
K
E
K
S
P
Q
A
Site 32
S422
M
K
P
S
K
E
K
S
P
Q
A
S
K
E
M
Site 33
S426
K
E
K
S
P
Q
A
S
K
E
M
S
A
L
Q
Site 34
S430
P
Q
A
S
K
E
M
S
A
L
Q
E
R
N
L
Site 35
T488
L
K
L
K
L
G
L
T
L
N
K
D
R
R
R
Site 36
T499
D
R
R
R
A
A
L
T
G
N
L
S
L
G
L
Site 37
T514
P
A
A
Q
P
Q
N
T
F
F
N
T
K
Y
G
Site 38
Y520
N
T
F
F
N
T
K
Y
G
E
S
G
N
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation