KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WDR33
Full Name:
WD repeat-containing protein 33
Alias:
FLJ11294; NET14; WD repeat domain 33; WD repeat-containing protein WDC146; WD33; WDC146; WD-repeat protein 33; WD-repeat protein WDC146
Type:
Adaptor/scaffold
Mass (Da):
145891
Number AA:
1336
UniProt ID:
Q9C0J8
International Prot ID:
IPI00106567
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000003
GO:0006139
GO:0006259
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
T
E
I
G
S
P
P
R
F
F
H
M
Site 2
Y27
Q
A
P
R
Q
L
F
Y
K
R
P
D
F
A
Q
Site 3
T42
Q
Q
A
M
Q
Q
L
T
F
D
G
K
R
M
R
Site 4
T56
R
K
A
V
N
R
K
T
I
D
Y
N
P
S
V
Site 5
Y59
V
N
R
K
T
I
D
Y
N
P
S
V
I
K
Y
Site 6
Y66
Y
N
P
S
V
I
K
Y
L
E
N
R
I
W
Q
Site 7
Y88
A
I
Q
P
D
A
G
Y
Y
N
D
L
V
P
P
Site 8
S114
T
T
K
F
V
R
T
S
T
N
K
V
K
C
P
Site 9
T115
T
K
F
V
R
T
S
T
N
K
V
K
C
P
V
Site 10
T136
P
E
G
R
R
L
V
T
G
A
S
S
G
E
F
Site 11
S139
R
R
L
V
T
G
A
S
S
G
E
F
T
L
W
Site 12
S162
T
I
L
Q
A
H
D
S
P
V
R
A
M
T
W
Site 13
Y184
L
T
A
D
H
G
G
Y
V
K
Y
W
Q
S
N
Site 14
S209
K
E
A
I
R
E
A
S
F
S
P
T
D
N
K
Site 15
S211
A
I
R
E
A
S
F
S
P
T
D
N
K
F
A
Site 16
T213
R
E
A
S
F
S
P
T
D
N
K
F
A
T
C
Site 17
T219
P
T
D
N
K
F
A
T
C
S
D
D
G
T
V
Site 18
S221
D
N
K
F
A
T
C
S
D
D
G
T
V
R
I
Site 19
S261
P
T
K
G
L
V
V
S
G
S
K
D
S
Q
Q
Site 20
S263
K
G
L
V
V
S
G
S
K
D
S
Q
Q
P
I
Site 21
S266
V
V
S
G
S
K
D
S
Q
Q
P
I
K
F
W
Site 22
T277
I
K
F
W
D
P
K
T
G
Q
S
L
A
T
L
Site 23
S280
W
D
P
K
T
G
Q
S
L
A
T
L
H
A
H
Site 24
T305
L
N
G
N
W
L
L
T
A
S
R
D
H
L
C
Site 25
S349
V
H
E
G
L
F
A
S
G
G
S
D
G
S
L
Site 26
S392
P
L
G
H
I
L
C
S
G
S
N
D
H
T
S
Site 27
S394
G
H
I
L
C
S
G
S
N
D
H
T
S
K
F
Site 28
S399
S
G
S
N
D
H
T
S
K
F
W
T
R
N
R
Site 29
T403
D
H
T
S
K
F
W
T
R
N
R
P
G
D
K
Site 30
Y415
G
D
K
M
R
D
R
Y
N
L
N
L
L
P
G
Site 31
S424
L
N
L
L
P
G
M
S
E
D
G
V
E
Y
D
Site 32
Y430
M
S
E
D
G
V
E
Y
D
D
L
E
P
N
S
Site 33
S437
Y
D
D
L
E
P
N
S
L
A
V
I
P
G
M
Site 34
S464
E
Q
M
G
K
D
E
S
N
E
I
E
M
T
I
Site 35
T470
E
S
N
E
I
E
M
T
I
P
G
L
D
W
G
Site 36
Y496
V
P
Q
K
K
V
P
Y
A
K
P
I
P
A
Q
Site 37
T537
K
L
E
E
K
K
K
T
Q
A
E
I
E
Q
E
Site 38
Y550
Q
E
M
A
T
L
Q
Y
T
N
P
Q
L
L
E
Site 39
S577
E
Q
I
Q
P
P
P
S
S
G
T
P
L
L
G
Site 40
S578
Q
I
Q
P
P
P
S
S
G
T
P
L
L
G
P
Site 41
T580
Q
P
P
P
S
S
G
T
P
L
L
G
P
Q
P
Site 42
S595
F
P
G
Q
G
P
M
S
Q
I
P
Q
G
F
Q
Site 43
S698
G
P
P
G
P
Q
G
S
S
G
P
Q
G
H
M
Site 44
S699
P
P
G
P
Q
G
S
S
G
P
Q
G
H
M
G
Site 45
T737
G
P
Q
G
P
P
G
T
Q
G
M
Q
G
P
P
Site 46
S764
G
I
Q
G
G
P
G
S
Q
G
I
Q
G
P
V
Site 47
S844
Q
G
P
P
P
Q
G
S
M
L
G
P
P
Q
E
Site 48
S858
E
L
R
G
P
P
G
S
Q
S
Q
Q
G
P
P
Site 49
S860
R
G
P
P
G
S
Q
S
Q
Q
G
P
P
Q
G
Site 50
S868
Q
Q
G
P
P
Q
G
S
L
G
P
P
P
Q
G
Site 51
S896
P
A
R
G
P
H
P
S
Q
G
P
I
P
F
Q
Site 52
T907
I
P
F
Q
Q
Q
K
T
P
L
L
G
D
G
P
Site 53
S924
P
F
N
Q
E
G
Q
S
T
G
P
P
P
L
I
Site 54
T925
F
N
Q
E
G
Q
S
T
G
P
P
P
L
I
P
Site 55
S959
P
G
P
N
K
G
D
S
R
G
P
P
N
H
H
Site 56
S978
S
E
R
R
H
E
Q
S
G
G
P
E
H
G
P
Site 57
S1014
P
D
F
P
D
D
F
S
R
P
D
D
F
H
P
Site 58
S1062
P
P
D
H
R
E
F
S
E
G
D
G
R
G
A
Site 59
S1103
F
R
G
R
R
E
E
S
F
R
R
G
A
P
P
Site 60
S1139
P
E
E
N
F
D
A
S
E
E
A
A
R
G
R
Site 61
T1155
L
R
G
R
G
R
G
T
P
R
G
G
R
K
G
Site 62
T1166
G
R
K
G
L
L
P
T
P
D
E
F
P
R
F
Site 63
S1181
E
G
G
R
K
P
D
S
W
D
G
N
R
E
P
Site 64
T1198
G
H
E
H
F
R
D
T
P
R
P
D
H
P
P
Site 65
S1210
H
P
P
H
D
G
H
S
P
A
S
R
E
R
S
Site 66
S1213
H
D
G
H
S
P
A
S
R
E
R
S
S
S
L
Site 67
S1217
S
P
A
S
R
E
R
S
S
S
L
Q
G
M
D
Site 68
S1218
P
A
S
R
E
R
S
S
S
L
Q
G
M
D
M
Site 69
S1219
A
S
R
E
R
S
S
S
L
Q
G
M
D
M
A
Site 70
S1227
L
Q
G
M
D
M
A
S
L
P
P
R
K
R
P
Site 71
S1254
M
E
A
P
G
G
P
S
E
D
R
G
G
K
G
Site 72
S1274
P
A
Q
R
V
P
K
S
G
R
S
S
S
L
D
Site 73
S1277
R
V
P
K
S
G
R
S
S
S
L
D
G
E
H
Site 74
S1278
V
P
K
S
G
R
S
S
S
L
D
G
E
H
H
Site 75
S1279
P
K
S
G
R
S
S
S
L
D
G
E
H
H
D
Site 76
Y1288
D
G
E
H
H
D
G
Y
H
R
D
E
P
F
G
Site 77
S1300
P
F
G
G
P
P
G
S
G
T
P
S
R
G
G
Site 78
T1302
G
G
P
P
G
S
G
T
P
S
R
G
G
R
S
Site 79
S1304
P
P
G
S
G
T
P
S
R
G
G
R
S
G
S
Site 80
S1309
T
P
S
R
G
G
R
S
G
S
N
W
G
R
G
Site 81
S1311
S
R
G
G
R
S
G
S
N
W
G
R
G
S
N
Site 82
S1317
G
S
N
W
G
R
G
S
N
M
N
S
G
P
P
Site 83
S1321
G
R
G
S
N
M
N
S
G
P
P
R
R
G
A
Site 84
S1329
G
P
P
R
R
G
A
S
R
G
G
G
R
G
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation