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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STLK6
Full Name:
STE20-related kinase adapter protein beta
Alias:
AL2S2; ALS2CR2; FLJ14731; ILP-interacting protein ILPIPA
Type:
Protein-serine kinase, STE group, STE20 family, STLK subfamily
Mass (Da):
47026
Number AA:
418
UniProt ID:
Q9C0K7
International Prot ID:
IPI00032099
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0032147
GO:0007049
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
S
L
L
D
C
F
C
T
S
R
T
Q
V
E
S
Site 2
T12
D
C
F
C
T
S
R
T
Q
V
E
S
L
R
P
Site 3
S16
T
S
R
T
Q
V
E
S
L
R
P
E
K
Q
S
Site 4
S23
S
L
R
P
E
K
Q
S
E
T
S
I
H
Q
Y
Site 5
Y30
S
E
T
S
I
H
Q
Y
L
V
D
E
P
T
L
Site 6
T36
Q
Y
L
V
D
E
P
T
L
S
W
S
R
P
S
Site 7
S38
L
V
D
E
P
T
L
S
W
S
R
P
S
T
R
Site 8
S40
D
E
P
T
L
S
W
S
R
P
S
T
R
A
S
Site 9
S43
T
L
S
W
S
R
P
S
T
R
A
S
E
V
L
Site 10
T44
L
S
W
S
R
P
S
T
R
A
S
E
V
L
C
Site 11
S47
S
R
P
S
T
R
A
S
E
V
L
C
S
T
N
Site 12
S52
R
A
S
E
V
L
C
S
T
N
V
S
H
Y
E
Site 13
S56
V
L
C
S
T
N
V
S
H
Y
E
L
Q
V
E
Site 14
T72
G
R
G
F
D
N
L
T
S
V
H
L
A
R
H
Site 15
S73
R
G
F
D
N
L
T
S
V
H
L
A
R
H
T
Site 16
T80
S
V
H
L
A
R
H
T
P
T
G
T
L
V
T
Site 17
Y122
R
H
P
N
I
T
T
Y
W
T
V
F
T
V
G
Site 18
S143
S
P
F
M
A
Y
G
S
A
S
Q
L
L
R
T
Site 19
T150
S
A
S
Q
L
L
R
T
Y
F
P
E
G
M
S
Site 20
Y151
A
S
Q
L
L
R
T
Y
F
P
E
G
M
S
E
Site 21
T159
F
P
E
G
M
S
E
T
L
I
R
N
I
L
F
Site 22
Y174
G
A
V
R
G
L
N
Y
L
H
Q
N
G
C
I
Site 23
S188
I
H
R
S
I
K
A
S
H
I
L
I
S
G
D
Site 24
S208
S
G
L
S
H
L
H
S
L
V
K
H
G
Q
R
Site 25
Y220
G
Q
R
H
R
A
V
Y
D
F
P
Q
F
S
T
Site 26
S228
D
F
P
Q
F
S
T
S
V
Q
P
W
L
S
P
Site 27
S234
T
S
V
Q
P
W
L
S
P
E
L
L
R
Q
D
Site 28
Y245
L
R
Q
D
L
H
G
Y
N
V
K
S
D
I
Y
Site 29
S249
L
H
G
Y
N
V
K
S
D
I
Y
S
V
G
I
Site 30
Y286
Q
K
L
K
G
P
P
Y
S
P
L
D
I
S
I
Site 31
S287
K
L
K
G
P
P
Y
S
P
L
D
I
S
I
F
Site 32
S292
P
Y
S
P
L
D
I
S
I
F
P
Q
S
E
S
Site 33
S297
D
I
S
I
F
P
Q
S
E
S
R
M
K
N
S
Site 34
S299
S
I
F
P
Q
S
E
S
R
M
K
N
S
Q
S
Site 35
S304
S
E
S
R
M
K
N
S
Q
S
G
V
D
S
G
Site 36
S306
S
R
M
K
N
S
Q
S
G
V
D
S
G
I
G
Site 37
S310
N
S
Q
S
G
V
D
S
G
I
G
E
S
V
L
Site 38
T322
S
V
L
V
S
S
G
T
H
T
V
N
S
D
R
Site 39
T324
L
V
S
S
G
T
H
T
V
N
S
D
R
L
H
Site 40
S327
S
G
T
H
T
V
N
S
D
R
L
H
T
P
S
Site 41
T332
V
N
S
D
R
L
H
T
P
S
S
K
T
F
S
Site 42
S334
S
D
R
L
H
T
P
S
S
K
T
F
S
P
A
Site 43
S335
D
R
L
H
T
P
S
S
K
T
F
S
P
A
F
Site 44
T337
L
H
T
P
S
S
K
T
F
S
P
A
F
F
S
Site 45
S359
Q
D
P
E
K
R
P
S
A
S
S
L
L
S
H
Site 46
S361
P
E
K
R
P
S
A
S
S
L
L
S
H
V
F
Site 47
S362
E
K
R
P
S
A
S
S
L
L
S
H
V
F
F
Site 48
S376
F
K
Q
M
K
E
E
S
Q
D
S
I
L
S
L
Site 49
S379
M
K
E
E
S
Q
D
S
I
L
S
L
L
P
P
Site 50
S382
E
S
Q
D
S
I
L
S
L
L
P
P
A
Y
N
Site 51
S392
P
P
A
Y
N
K
P
S
I
S
L
P
P
V
L
Site 52
S394
A
Y
N
K
P
S
I
S
L
P
P
V
L
P
W
Site 53
T402
L
P
P
V
L
P
W
T
E
P
E
C
D
F
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation