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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACTR6
Full Name:
Actin-related protein 6
Alias:
hARPX
Type:
Mass (Da):
45810
Number AA:
396
UniProt ID:
Q9GZN1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
L
V
L
D
N
G
A
Y
N
A
K
I
G
Y
S
Site 2
S32
I
P
N
C
Q
F
R
S
K
T
A
R
L
K
T
Site 3
T34
N
C
Q
F
R
S
K
T
A
R
L
K
T
F
T
Site 4
T39
S
K
T
A
R
L
K
T
F
T
A
N
Q
I
D
Site 5
T41
T
A
R
L
K
T
F
T
A
N
Q
I
D
E
I
Site 6
Y56
K
D
P
S
G
L
F
Y
I
L
P
F
Q
K
G
Site 7
Y77
V
Q
R
Q
V
W
D
Y
L
F
G
K
E
M
Y
Site 8
Y84
Y
L
F
G
K
E
M
Y
Q
V
D
F
L
D
T
Site 9
S108
N
F
T
S
I
Q
E
S
M
N
E
I
L
F
E
Site 10
S131
R
V
N
A
G
A
L
S
A
H
R
Y
F
R
D
Site 11
Y135
G
A
L
S
A
H
R
Y
F
R
D
N
P
S
E
Site 12
Y160
S
F
T
H
I
V
P
Y
C
R
S
K
K
K
K
Site 13
Y190
H
L
K
E
I
I
S
Y
R
Q
L
H
V
M
D
Site 14
T199
Q
L
H
V
M
D
E
T
H
V
I
N
Q
V
K
Site 15
Y211
Q
V
K
E
D
V
C
Y
V
S
Q
D
F
Y
R
Site 16
Y217
C
Y
V
S
Q
D
F
Y
R
D
M
D
I
A
K
Site 17
Y236
E
N
T
V
M
I
D
Y
V
L
P
D
F
S
T
Site 18
T243
Y
V
L
P
D
F
S
T
I
K
K
G
F
C
K
Site 19
S258
P
R
E
E
M
V
L
S
G
K
Y
K
S
G
E
Site 20
Y261
E
M
V
L
S
G
K
Y
K
S
G
E
Q
I
L
Site 21
S263
V
L
S
G
K
Y
K
S
G
E
Q
I
L
R
L
Site 22
S285
P
E
I
L
F
N
P
S
D
I
G
I
Q
E
M
Site 23
S301
I
P
E
A
I
V
Y
S
I
Q
N
L
P
E
E
Site 24
Y334
P
G
F
R
D
R
V
Y
S
E
V
R
C
L
T
Site 25
S335
G
F
R
D
R
V
Y
S
E
V
R
C
L
T
P
Site 26
T341
Y
S
E
V
R
C
L
T
P
T
D
Y
D
V
S
Site 27
T343
E
V
R
C
L
T
P
T
D
Y
D
V
S
V
V
Site 28
S348
T
P
T
D
Y
D
V
S
V
V
L
P
E
N
P
Site 29
T357
V
L
P
E
N
P
I
T
Y
A
W
E
G
G
K
Site 30
Y358
L
P
E
N
P
I
T
Y
A
W
E
G
G
K
L
Site 31
S367
W
E
G
G
K
L
I
S
E
N
D
D
F
E
D
Site 32
Y382
M
V
V
T
R
E
D
Y
E
E
N
G
H
S
V
Site 33
S388
D
Y
E
E
N
G
H
S
V
C
E
E
K
F
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation