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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX24
Full Name:
ATP-dependent RNA helicase DDX24
Alias:
DEAD box protein 24
Type:
Helicase; EC 3.6.1.-
Mass (Da):
96332
Number AA:
859
UniProt ID:
Q9GZR7
International Prot ID:
IPI00006987
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004004
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0016070
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
K
L
K
D
T
K
S
R
P
K
Q
S
Site 2
S8
M
K
L
K
D
T
K
S
R
P
K
Q
S
S
C
Site 3
S14
K
S
R
P
K
Q
S
S
C
G
K
F
Q
T
K
Site 4
Y56
C
F
E
E
L
T
D
Y
Q
L
V
S
P
A
K
Site 5
S60
L
T
D
Y
Q
L
V
S
P
A
K
N
P
S
S
Site 6
S66
V
S
P
A
K
N
P
S
S
L
F
S
K
E
A
Site 7
S67
S
P
A
K
N
P
S
S
L
F
S
K
E
A
P
Site 8
S70
K
N
P
S
S
L
F
S
K
E
A
P
K
R
K
Site 9
S82
K
R
K
A
Q
A
V
S
E
E
E
E
E
E
E
Site 10
S92
E
E
E
E
E
G
K
S
S
S
P
K
K
K
I
Site 11
S93
E
E
E
E
G
K
S
S
S
P
K
K
K
I
K
Site 12
S94
E
E
E
G
K
S
S
S
P
K
K
K
I
K
L
Site 13
S104
K
K
I
K
L
K
K
S
K
N
V
A
T
E
G
Site 14
T114
V
A
T
E
G
T
S
T
Q
K
E
F
E
V
K
Site 15
S166
G
K
K
G
L
E
P
S
Q
S
T
A
A
K
V
Site 16
S168
K
G
L
E
P
S
Q
S
T
A
A
K
V
P
K
Site 17
T169
G
L
E
P
S
Q
S
T
A
A
K
V
P
K
K
Site 18
T179
K
V
P
K
K
A
K
T
W
I
P
E
V
H
D
Site 19
S192
H
D
Q
K
A
D
V
S
A
W
K
D
L
F
V
Site 20
S268
R
N
A
A
P
P
P
S
N
T
E
A
P
P
G
Site 21
T270
A
A
P
P
P
S
N
T
E
A
P
P
G
E
T
Site 22
T279
A
P
P
G
E
T
R
T
E
A
G
A
E
T
R
Site 23
T285
R
T
E
A
G
A
E
T
R
S
P
G
K
A
E
Site 24
S287
E
A
G
A
E
T
R
S
P
G
K
A
E
A
E
Site 25
S295
P
G
K
A
E
A
E
S
D
A
L
P
D
D
T
Site 26
T302
S
D
A
L
P
D
D
T
V
I
E
S
E
A
L
Site 27
S306
P
D
D
T
V
I
E
S
E
A
L
P
S
D
I
Site 28
S311
I
E
S
E
A
L
P
S
D
I
A
A
E
A
R
Site 29
T321
A
A
E
A
R
A
K
T
G
G
T
V
S
D
Q
Site 30
T324
A
R
A
K
T
G
G
T
V
S
D
Q
A
L
L
Site 31
S343
D
A
G
E
G
P
S
S
L
I
R
E
K
P
V
Site 32
S377
K
Q
E
L
D
D
K
S
A
T
C
K
A
Y
P
Site 33
Y383
K
S
A
T
C
K
A
Y
P
K
R
P
L
L
G
Site 34
T394
P
L
L
G
L
V
L
T
P
T
R
E
L
A
V
Site 35
S426
A
I
L
V
G
G
M
S
T
Q
K
Q
Q
R
M
Site 36
Y457
E
L
I
K
E
K
H
Y
H
L
R
N
L
R
Q
Site 37
S486
K
G
H
F
A
E
L
S
Q
L
L
E
M
L
N
Site 38
S495
L
L
E
M
L
N
D
S
Q
Y
N
P
K
R
Q
Site 39
Y497
E
M
L
N
D
S
Q
Y
N
P
K
R
Q
T
L
Site 40
T503
Q
Y
N
P
K
R
Q
T
L
V
F
S
A
T
L
Site 41
T509
Q
T
L
V
F
S
A
T
L
T
L
V
H
Q
A
Site 42
T511
L
V
F
S
A
T
L
T
L
V
H
Q
A
P
A
Site 43
T532
H
T
K
K
M
D
K
T
A
K
L
D
L
L
M
Site 44
T554
K
P
K
V
I
D
L
T
R
N
E
A
T
V
E
Site 45
Y578
E
T
D
E
K
D
F
Y
L
Y
Y
F
L
M
Q
Site 46
Y580
D
E
K
D
F
Y
L
Y
Y
F
L
M
Q
Y
P
Site 47
Y581
E
K
D
F
Y
L
Y
Y
F
L
M
Q
Y
P
G
Site 48
Y662
K
V
Q
H
V
I
H
Y
Q
V
P
R
T
S
E
Site 49
S668
H
Y
Q
V
P
R
T
S
E
I
Y
V
H
R
S
Site 50
Y671
V
P
R
T
S
E
I
Y
V
H
R
S
G
R
T
Site 51
S675
S
E
I
Y
V
H
R
S
G
R
T
A
R
A
T
Site 52
T682
S
G
R
T
A
R
A
T
N
E
G
L
S
L
M
Site 53
T705
N
F
K
K
I
Y
K
T
L
K
K
D
E
D
I
Site 54
Y721
L
F
P
V
Q
T
K
Y
M
D
V
V
K
E
R
Site 55
S738
L
A
R
Q
I
E
K
S
E
Y
R
N
F
Q
A
Site 56
Y740
R
Q
I
E
K
S
E
Y
R
N
F
Q
A
C
L
Site 57
Y768
I
E
L
E
E
D
M
Y
K
G
G
K
A
D
Q
Site 58
S797
K
E
L
R
H
L
L
S
Q
P
L
F
T
E
S
Site 59
S804
S
Q
P
L
F
T
E
S
Q
K
T
K
Y
P
T
Site 60
T807
L
F
T
E
S
Q
K
T
K
Y
P
T
Q
S
G
Site 61
Y809
T
E
S
Q
K
T
K
Y
P
T
Q
S
G
K
P
Site 62
T811
S
Q
K
T
K
Y
P
T
Q
S
G
K
P
P
L
Site 63
S813
K
T
K
Y
P
T
Q
S
G
K
P
P
L
L
V
Site 64
S821
G
K
P
P
L
L
V
S
A
P
S
K
S
E
S
Site 65
S828
S
A
P
S
K
S
E
S
A
L
S
C
L
S
K
Site 66
S831
S
K
S
E
S
A
L
S
C
L
S
K
Q
K
K
Site 67
S834
E
S
A
L
S
C
L
S
K
Q
K
K
K
K
T
Site 68
T841
S
K
Q
K
K
K
K
T
K
K
P
K
E
P
Q
Site 69
S855
Q
P
E
Q
P
Q
P
S
T
S
A
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation