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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNAI2
Full Name:
Dynein intermediate chain 2, axonemal
Alias:
Axonemal dynein intermediate chain 2; Dynein intermediate chain 2; Dynein, axonemal, intermediate chain 2; Dynein, axonemal, intermediate polypeptide 2
Type:
Motor protein
Mass (Da):
68851
Number AA:
605
UniProt ID:
Q9GZS0
International Prot ID:
IPI00304288
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005858
GO:0035085
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0042384
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
E
I
V
Y
V
Y
V
K
K
R
S
E
F
Site 2
S21
F
G
K
Q
C
N
F
S
D
R
Q
A
E
L
N
Site 3
T49
V
E
R
N
P
V
D
T
G
I
Q
C
S
I
S
Site 4
S54
V
D
T
G
I
Q
C
S
I
S
M
S
E
H
E
Site 5
S56
T
G
I
Q
C
S
I
S
M
S
E
H
E
A
N
Site 6
S58
I
Q
C
S
I
S
M
S
E
H
E
A
N
S
E
Site 7
S64
M
S
E
H
E
A
N
S
E
R
F
E
M
E
T
Site 8
T71
S
E
R
F
E
M
E
T
R
G
V
N
H
V
E
Site 9
T93
N
P
L
E
L
E
Q
T
I
R
F
R
K
K
V
Site 10
Y106
K
V
E
K
D
E
N
Y
V
N
A
I
M
Q
L
Site 11
Y130
Q
N
N
A
I
D
I
Y
E
E
Y
F
N
D
E
Site 12
Y133
A
I
D
I
Y
E
E
Y
F
N
D
E
E
A
M
Site 13
S148
E
V
M
E
E
D
P
S
A
K
T
I
N
V
F
Site 14
T166
Q
E
I
K
R
A
A
T
H
L
S
W
H
P
D
Site 15
S169
K
R
A
A
T
H
L
S
W
H
P
D
G
N
R
Site 16
S183
R
K
L
A
V
A
Y
S
C
L
D
F
Q
R
A
Site 17
S196
R
A
P
V
G
M
S
S
D
S
Y
I
W
D
L
Site 18
S198
P
V
G
M
S
S
D
S
Y
I
W
D
L
E
N
Site 19
Y199
V
G
M
S
S
D
S
Y
I
W
D
L
E
N
P
Site 20
T221
K
P
S
S
P
L
V
T
L
E
F
N
P
K
D
Site 21
S229
L
E
F
N
P
K
D
S
H
V
L
L
G
G
C
Site 22
T246
G
Q
I
A
C
W
D
T
R
K
G
S
L
V
A
Site 23
S250
C
W
D
T
R
K
G
S
L
V
A
E
L
S
T
Site 24
S256
G
S
L
V
A
E
L
S
T
I
E
S
S
H
R
Site 25
T257
S
L
V
A
E
L
S
T
I
E
S
S
H
R
D
Site 26
S260
A
E
L
S
T
I
E
S
S
H
R
D
P
V
Y
Site 27
S261
E
L
S
T
I
E
S
S
H
R
D
P
V
Y
G
Site 28
Y267
S
S
H
R
D
P
V
Y
G
T
I
W
L
Q
S
Site 29
T278
W
L
Q
S
K
T
G
T
E
C
F
S
A
S
T
Site 30
S298
W
W
D
I
R
K
M
S
E
P
T
E
V
V
I
Site 31
T301
I
R
K
M
S
E
P
T
E
V
V
I
L
D
I
Site 32
T309
E
V
V
I
L
D
I
T
K
K
E
Q
L
E
N
Site 33
T331
E
F
E
S
T
L
P
T
K
F
M
V
G
T
E
Site 34
T337
P
T
K
F
M
V
G
T
E
Q
G
I
V
I
S
Site 35
S344
T
E
Q
G
I
V
I
S
C
N
R
K
A
K
T
Site 36
T351
S
C
N
R
K
A
K
T
S
A
E
K
I
V
C
Site 37
S352
C
N
R
K
A
K
T
S
A
E
K
I
V
C
T
Site 38
T359
S
A
E
K
I
V
C
T
F
P
G
H
H
G
P
Site 39
Y368
P
G
H
H
G
P
I
Y
A
L
Q
R
N
P
F
Site 40
Y376
A
L
Q
R
N
P
F
Y
P
K
N
F
L
T
V
Site 41
S392
D
W
T
A
R
I
W
S
E
D
S
R
E
S
S
Site 42
S395
A
R
I
W
S
E
D
S
R
E
S
S
I
M
W
Site 43
S399
S
E
D
S
R
E
S
S
I
M
W
T
K
Y
H
Site 44
Y405
S
S
I
M
W
T
K
Y
H
M
A
Y
L
T
D
Site 45
Y409
W
T
K
Y
H
M
A
Y
L
T
D
A
A
W
S
Site 46
T411
K
Y
H
M
A
Y
L
T
D
A
A
W
S
P
V
Site 47
T445
M
F
E
Q
C
D
P
T
L
S
L
K
V
C
D
Site 48
T477
G
S
Q
L
G
T
T
T
L
L
E
V
S
P
G
Site 49
S486
L
E
V
S
P
G
L
S
T
L
Q
R
N
E
K
Site 50
T504
S
S
M
F
E
R
E
T
R
R
E
K
I
L
E
Site 51
T533
E
G
R
D
E
E
Q
T
D
E
E
L
A
V
D
Site 52
T571
E
A
D
A
I
K
L
T
P
V
P
Q
Q
P
S
Site 53
S578
T
P
V
P
Q
Q
P
S
P
E
E
D
Q
V
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation