PhosphoNET

           
Protein Info 
   
Short Name:  EGLN1
Full Name:  Egl nine homolog 1
Alias:  EC 1.14.11.-; EGL nine (C.elegans) homologue 1; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; Hypoxia-inducible factor prolyl hydroxylase 2; PHD2; ZMYND6
Type:  Oxidoreductase, Biosynthesis of Secondary Metabolites group, Diterpenoid biosynthesis family
Mass (Da):  46021
Number AA:  426
UniProt ID:  Q9GZT9
International Prot ID:  IPI00004928
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0044424  GO:0044444 Uniprot OncoNet
Molecular Function:  GO:0031418  GO:0005506  GO:0016702 PhosphoSite+ KinaseNET
Biological Process:  GO:0043433  GO:0055114  GO:0032364 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12SGGPGGPSPSERDRQ
Site 2S14GPGGPSPSERDRQYC
Site 3Y20PSERDRQYCELCGKM
Site 4S34MENLLRCSRCRSSFY
Site 5Y41SRCRSSFYCCKEHQR
Site 6S61HKLVCQGSEGALGHG
Site 7S75GVGPHQHSGPAPPAA
Site 8S104AARRDNASGDAAKGK
Site 9S125ADPAAAASPCRAAAG
Site 10S154EEPPARSSLFQEKAN
Site 11Y163FQEKANLYPPSNTPG
Site 12S166KANLYPPSNTPGDAL
Site 13T168NLYPPSNTPGDALSP
Site 14S174NTPGDALSPGGGLRP
Site 15T232EVRALHDTGKFTDGQ
Site 16S242FTDGQLVSQKSDSSK
Site 17S245GQLVSQKSDSSKDIR
Site 18S247LVSQKSDSSKDIRGD
Site 19T257DIRGDKITWIEGKEP
Site 20Y303TKAMVACYPGNGTGY
Site 21Y310YPGNGTGYVRHVDNP
Site 22S368DRLLFFWSDRRNPHE
Site 23Y380PHEVQPAYATRYAIT
Site 24Y390RYAITVWYFDADERA
Site 25Y403RARAKVKYLTGEKGV
Site 26T405RAKVKYLTGEKGVRV
Site 27S420ELNKPSDSVGKDVF_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation