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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAB
Full Name:
Linker for activation of T-cells family member 2
Alias:
HSPC046; Hypothetical protein FLJ11237; LAT2; Linker for activation of B cells; Linker for activation of T cells family, member 2; Membrane-associated adaptor molecule; Non-T cell activation linker; NTAL; Similar to Williams-Beuren syndrome chromosome region 5; WBS15 protein; WBS15 splice variant 1; WBS15 splice variant 2; WBSCR15; WBSCR5; Wbscr5; Williams-Beuren syndrome protein Wbscr5; WSCR5
Type:
Adapter/scaffold protein
Mass (Da):
26550
Number AA:
243
UniProt ID:
Q9GZY6
International Prot ID:
IPI00395993
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0045121
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0042169
PhosphoSite+
KinaseNET
Biological Process:
GO:0042113
GO:0050853
GO:0019722
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
A
S
L
C
V
R
C
S
R
P
G
A
K
R
S
Site 2
S36
S
R
P
G
A
K
R
S
E
K
I
Y
Q
Q
R
Site 3
Y40
A
K
R
S
E
K
I
Y
Q
Q
R
S
L
R
E
Site 4
S44
E
K
I
Y
Q
Q
R
S
L
R
E
D
Q
Q
S
Site 5
S51
S
L
R
E
D
Q
Q
S
F
T
G
S
R
T
Y
Site 6
T53
R
E
D
Q
Q
S
F
T
G
S
R
T
Y
S
L
Site 7
S55
D
Q
Q
S
F
T
G
S
R
T
Y
S
L
V
G
Site 8
T57
Q
S
F
T
G
S
R
T
Y
S
L
V
G
Q
A
Site 9
Y58
S
F
T
G
S
R
T
Y
S
L
V
G
Q
A
W
Site 10
S59
F
T
G
S
R
T
Y
S
L
V
G
Q
A
W
P
Site 11
Y84
K
D
K
L
L
Q
F
Y
P
S
L
E
D
P
A
Site 12
S86
K
L
L
Q
F
Y
P
S
L
E
D
P
A
S
S
Site 13
S92
P
S
L
E
D
P
A
S
S
R
Y
Q
N
F
S
Site 14
Y95
E
D
P
A
S
S
R
Y
Q
N
F
S
K
G
S
Site 15
S99
S
S
R
Y
Q
N
F
S
K
G
S
R
H
G
S
Site 16
S106
S
K
G
S
R
H
G
S
E
E
A
Y
I
D
P
Site 17
Y110
R
H
G
S
E
E
A
Y
I
D
P
I
A
M
E
Site 18
Y118
I
D
P
I
A
M
E
Y
Y
N
W
G
R
F
S
Site 19
Y119
D
P
I
A
M
E
Y
Y
N
W
G
R
F
S
K
Site 20
S135
P
E
D
D
D
A
N
S
Y
E
N
V
L
I
C
Site 21
Y136
E
D
D
D
A
N
S
Y
E
N
V
L
I
C
K
Site 22
S176
A
L
K
T
G
P
T
S
G
L
C
P
S
A
S
Site 23
S181
P
T
S
G
L
C
P
S
A
S
P
E
E
D
E
Site 24
S183
S
G
L
C
P
S
A
S
P
E
E
D
E
E
S
Site 25
S190
S
P
E
E
D
E
E
S
E
D
Y
Q
N
S
A
Site 26
Y193
E
D
E
E
S
E
D
Y
Q
N
S
A
S
I
H
Site 27
S196
E
S
E
D
Y
Q
N
S
A
S
I
H
Q
W
R
Site 28
S198
E
D
Y
Q
N
S
A
S
I
H
Q
W
R
E
S
Site 29
S217
G
Q
L
Q
R
E
A
S
P
G
P
V
G
S
P
Site 30
S223
A
S
P
G
P
V
G
S
P
D
E
E
D
G
E
Site 31
Y233
E
E
D
G
E
P
D
Y
V
N
G
E
V
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation