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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBA5
Full Name:
Ubiquitin-like modifier-activating enzyme 5
Alias:
FLJ23251; ThiFP1; UBA5, ubiquitin-activating enzyme E1; UBE1DC1; Ubiquitin-activating enzyme 5; Ubiquitin-activating enzyme E1 domain-containing protein 1; Ubiquitin-like modifier activating enzyme 5; UFM1-activating enzyme
Type:
Ubiquitin conjugating system
Mass (Da):
44863
Number AA:
404
UniProt ID:
Q9GZZ9
International Prot ID:
IPI00015736
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0016491
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0006511
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
E
S
V
E
R
L
Q
Q
R
Site 2
S24
R
E
L
A
Q
E
R
S
L
Q
V
P
R
S
G
Site 3
S30
R
S
L
Q
V
P
R
S
G
D
G
G
G
G
R
Site 4
S44
R
V
R
I
E
K
M
S
S
E
V
V
D
S
N
Site 5
S45
V
R
I
E
K
M
S
S
E
V
V
D
S
N
P
Site 6
S50
M
S
S
E
V
V
D
S
N
P
Y
S
R
L
M
Site 7
Y53
E
V
V
D
S
N
P
Y
S
R
L
M
A
L
K
Site 8
S54
V
V
D
S
N
P
Y
S
R
L
M
A
L
K
R
Site 9
S66
L
K
R
M
G
I
V
S
D
Y
E
K
I
R
T
Site 10
Y68
R
M
G
I
V
S
D
Y
E
K
I
R
T
F
A
Site 11
Y105
G
K
L
L
L
F
D
Y
D
K
V
E
L
A
N
Site 12
T134
K
V
Q
A
A
E
H
T
L
R
N
I
N
P
D
Site 13
Y149
V
L
F
E
V
H
N
Y
N
I
T
T
V
E
N
Site 14
S165
Q
H
F
M
D
R
I
S
N
G
G
L
E
E
G
Site 15
T193
E
A
R
M
T
I
N
T
A
C
N
E
L
G
Q
Site 16
T201
A
C
N
E
L
G
Q
T
W
M
E
S
G
V
S
Site 17
S208
T
W
M
E
S
G
V
S
E
N
A
V
S
G
H
Site 18
T243
A
A
N
I
D
E
K
T
L
K
R
E
G
V
C
Site 19
S347
E
W
G
I
E
L
V
S
E
V
S
E
E
E
L
Site 20
S358
E
E
E
L
K
N
F
S
G
P
V
P
D
L
P
Site 21
T369
P
D
L
P
E
G
I
T
V
A
Y
T
I
P
K
Site 22
Y372
P
E
G
I
T
V
A
Y
T
I
P
K
K
Q
E
Site 23
T373
E
G
I
T
V
A
Y
T
I
P
K
K
Q
E
D
Site 24
S381
I
P
K
K
Q
E
D
S
V
T
E
L
T
V
E
Site 25
T383
K
K
Q
E
D
S
V
T
E
L
T
V
E
D
S
Site 26
T386
E
D
S
V
T
E
L
T
V
E
D
S
G
E
S
Site 27
S390
T
E
L
T
V
E
D
S
G
E
S
L
E
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation