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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADAM19
Full Name:
Disintegrin and metalloproteinase domain-containing protein 19
Alias:
Meltrin-beta;Metalloprotease and disintegrin dendritic antigen marker
Type:
Mass (Da):
105039
Number AA:
956
UniProt ID:
Q9H013
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
A
A
R
E
P
G
W
T
S
K
G
S
E
E
G
Site 2
S32
A
R
E
P
G
W
T
S
K
G
S
E
E
G
S
Site 3
S35
P
G
W
T
S
K
G
S
E
E
G
S
P
K
L
Site 4
S39
S
K
G
S
E
E
G
S
P
K
L
Q
H
E
L
Site 5
S54
I
I
P
Q
W
K
T
S
E
S
P
V
R
E
K
Site 6
S56
P
Q
W
K
T
S
E
S
P
V
R
E
K
H
P
Site 7
Y92
E
Q
L
F
A
P
S
Y
T
E
T
H
Y
T
S
Site 8
T95
F
A
P
S
Y
T
E
T
H
Y
T
S
S
G
N
Site 9
Y97
P
S
Y
T
E
T
H
Y
T
S
S
G
N
P
Q
Site 10
T98
S
Y
T
E
T
H
Y
T
S
S
G
N
P
Q
T
Site 11
T105
T
S
S
G
N
P
Q
T
T
T
R
K
L
E
D
Site 12
T123
Y
H
G
T
V
R
E
T
E
L
S
S
V
T
L
Site 13
S126
T
V
R
E
T
E
L
S
S
V
T
L
S
T
C
Site 14
S127
V
R
E
T
E
L
S
S
V
T
L
S
T
C
R
Site 15
S131
E
L
S
S
V
T
L
S
T
C
R
G
I
R
G
Site 16
Y148
T
V
S
S
N
L
S
Y
V
I
E
P
L
P
D
Site 17
S156
V
I
E
P
L
P
D
S
K
G
Q
H
L
I
Y
Site 18
Y163
S
K
G
Q
H
L
I
Y
R
S
E
H
L
K
P
Site 19
T184
F
E
H
S
K
P
T
T
R
D
W
A
L
Q
F
Site 20
Y212
E
D
L
N
S
M
K
Y
V
E
L
Y
L
V
A
Site 21
S737
K
L
G
Q
L
K
P
S
A
L
P
S
K
L
R
Site 22
S741
L
K
P
S
A
L
P
S
K
L
R
Q
Q
F
S
Site 23
S748
S
K
L
R
Q
Q
F
S
C
P
F
R
V
S
Q
Site 24
S754
F
S
C
P
F
R
V
S
Q
N
S
G
T
G
H
Site 25
S757
P
F
R
V
S
Q
N
S
G
T
G
H
A
N
P
Site 26
T765
G
T
G
H
A
N
P
T
F
K
L
Q
T
P
Q
Site 27
T770
N
P
T
F
K
L
Q
T
P
Q
G
K
R
K
V
Site 28
T780
G
K
R
K
V
I
N
T
P
E
I
L
R
K
P
Site 29
S788
P
E
I
L
R
K
P
S
Q
P
P
P
R
P
P
Site 30
Y798
P
P
R
P
P
P
D
Y
L
R
G
G
S
P
P
Site 31
S803
P
D
Y
L
R
G
G
S
P
P
A
P
L
P
A
Site 32
S813
A
P
L
P
A
H
L
S
R
A
A
R
N
S
P
Site 33
S819
L
S
R
A
A
R
N
S
P
G
P
G
S
Q
I
Site 34
S824
R
N
S
P
G
P
G
S
Q
I
E
R
T
E
S
Site 35
T829
P
G
S
Q
I
E
R
T
E
S
S
R
R
P
P
Site 36
S831
S
Q
I
E
R
T
E
S
S
R
R
P
P
P
S
Site 37
S832
Q
I
E
R
T
E
S
S
R
R
P
P
P
S
R
Site 38
S838
S
S
R
R
P
P
P
S
R
P
I
P
P
A
P
Site 39
S850
P
A
P
N
C
I
V
S
Q
D
F
S
R
P
R
Site 40
S854
C
I
V
S
Q
D
F
S
R
P
R
P
P
Q
K
Site 41
S873
N
P
V
P
G
R
R
S
L
P
R
P
G
G
A
Site 42
S881
L
P
R
P
G
G
A
S
P
L
R
P
P
G
A
Site 43
S893
P
G
A
G
P
Q
Q
S
R
P
L
A
A
L
A
Site 44
T928
G
R
C
R
V
E
K
T
K
Q
F
M
L
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation