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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLPB
Full Name:
Caseinolytic peptidase B protein homolog
Alias:
caseinolytic peptidase B; ClpB caseinolytic peptidase B; FLJ13152; HSP78; SKD3; suppressor of potassium transport defect 3
Type:
Unknown function
Mass (Da):
78729
Number AA:
707
UniProt ID:
Q9H078
International Prot ID:
IPI00006615
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0017111
PhosphoSite+
KinaseNET
Biological Process:
GO:0034605
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
L
L
L
R
L
L
R
S
P
T
L
R
G
H
G
Site 2
T25
L
R
L
L
R
S
P
T
L
R
G
H
G
G
A
Site 3
S33
L
R
G
H
G
G
A
S
G
R
N
V
T
T
G
Site 4
T38
G
A
S
G
R
N
V
T
T
G
S
L
G
E
P
Site 5
S41
G
R
N
V
T
T
G
S
L
G
E
P
Q
W
L
Site 6
T52
P
Q
W
L
R
V
A
T
G
G
R
P
G
T
S
Site 7
T58
A
T
G
G
R
P
G
T
S
P
A
L
F
S
G
Site 8
S59
T
G
G
R
P
G
T
S
P
A
L
F
S
G
R
Site 9
S64
G
T
S
P
A
L
F
S
G
R
G
A
A
T
G
Site 10
T80
R
Q
G
G
R
F
D
T
K
C
L
A
A
A
T
Site 11
T97
R
L
P
G
P
E
E
T
L
P
G
Q
D
S
W
Site 12
S103
E
T
L
P
G
Q
D
S
W
N
G
V
P
S
R
Site 13
S109
D
S
W
N
G
V
P
S
R
A
G
L
G
M
C
Site 14
Y127
A
A
L
V
V
H
C
Y
S
K
S
P
S
N
K
Site 15
S128
A
L
V
V
H
C
Y
S
K
S
P
S
N
K
D
Site 16
S130
V
V
H
C
Y
S
K
S
P
S
N
K
D
A
A
Site 17
S132
H
C
Y
S
K
S
P
S
N
K
D
A
A
L
L
Site 18
S155
Q
E
V
S
R
L
L
S
E
G
A
D
V
N
A
Site 19
S200
P
N
L
G
D
D
F
S
S
V
Y
K
T
A
K
Site 20
S201
N
L
G
D
D
F
S
S
V
Y
K
T
A
K
E
Site 21
T205
D
F
S
S
V
Y
K
T
A
K
E
Q
G
I
H
Site 22
S213
A
K
E
Q
G
I
H
S
L
E
D
G
G
Q
D
Site 23
T227
D
G
A
S
R
H
I
T
N
Q
W
T
S
A
L
Site 24
S263
N
R
L
N
N
R
A
S
F
K
G
C
T
A
L
Site 25
T281
V
L
A
D
D
Y
R
T
V
K
E
L
L
D
G
Site 26
T301
Q
R
N
E
M
G
H
T
P
L
D
Y
A
R
E
Site 27
Y305
M
G
H
T
P
L
D
Y
A
R
E
G
E
V
M
Site 28
S318
V
M
K
L
L
R
T
S
E
A
K
Y
Q
E
K
Site 29
Y322
L
R
T
S
E
A
K
Y
Q
E
K
Q
R
K
R
Site 30
Y369
R
R
K
E
N
G
W
Y
D
E
E
H
P
L
V
Site 31
S412
G
F
I
R
L
D
M
S
E
F
Q
E
R
H
E
Site 32
S426
E
V
A
K
F
I
G
S
P
P
G
Y
V
G
H
Site 33
Y430
F
I
G
S
P
P
G
Y
V
G
H
E
E
G
G
Site 34
T477
L
F
D
E
G
R
L
T
D
G
K
G
K
T
I
Site 35
S499
I
M
T
S
N
V
A
S
D
E
I
A
Q
H
A
Site 36
S531
N
L
G
D
V
Q
I
S
D
K
I
T
I
S
K
Site 37
T535
V
Q
I
S
D
K
I
T
I
S
K
N
F
K
E
Site 38
Y613
A
D
V
L
V
D
G
Y
N
V
H
Y
G
A
R
Site 39
Y617
V
D
G
Y
N
V
H
Y
G
A
R
S
I
K
H
Site 40
T652
G
G
C
T
L
R
I
T
V
E
D
S
D
K
Q
Site 41
S656
L
R
I
T
V
E
D
S
D
K
Q
L
L
K
S
Site 42
S663
S
D
K
Q
L
L
K
S
P
E
L
P
S
P
Q
Site 43
S668
L
K
S
P
E
L
P
S
P
Q
A
E
K
R
L
Site 44
S687
L
E
I
I
D
K
D
S
K
T
R
R
L
D
I
Site 45
T689
I
I
D
K
D
S
K
T
R
R
L
D
I
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation