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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NBPF3
Full Name:
Neuroblastoma breakpoint family member 3
Alias:
Protein AE2;Protein SHIIIa4
Type:
Mass (Da):
72951
Number AA:
633
UniProt ID:
Q9H094
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
T
V
Q
G
F
Q
W
T
L
R
G
P
D
V
E
Site 2
S22
R
G
P
D
V
E
T
S
P
F
G
A
P
R
A
Site 3
S31
F
G
A
P
R
A
A
S
H
G
V
G
R
H
Q
Site 4
T44
H
Q
E
L
R
D
P
T
V
P
G
P
T
S
S
Site 5
T49
D
P
T
V
P
G
P
T
S
S
A
T
N
V
S
Site 6
S50
P
T
V
P
G
P
T
S
S
A
T
N
V
S
M
Site 7
S60
T
N
V
S
M
V
V
S
A
G
P
W
S
G
E
Site 8
S65
V
V
S
A
G
P
W
S
G
E
K
A
E
M
N
Site 9
Y116
N
R
Q
N
N
Y
D
Y
E
D
C
K
D
L
I
Site 10
S125
D
C
K
D
L
I
K
S
M
L
R
D
E
R
L
Site 11
T134
L
R
D
E
R
L
L
T
E
E
K
L
A
E
E
Site 12
Y151
Q
A
E
E
L
R
Q
Y
K
V
L
V
H
S
Q
Site 13
S157
Q
Y
K
V
L
V
H
S
Q
E
R
E
L
T
Q
Site 14
T163
H
S
Q
E
R
E
L
T
Q
L
R
E
K
L
Q
Site 15
S176
L
Q
E
G
R
D
A
S
R
S
L
N
Q
H
L
Site 16
S178
E
G
R
D
A
S
R
S
L
N
Q
H
L
Q
A
Site 17
T188
Q
H
L
Q
A
L
L
T
P
D
E
P
D
N
S
Site 18
S195
T
P
D
E
P
D
N
S
Q
G
R
D
L
R
E
Site 19
S219
Q
H
L
V
Q
K
L
S
P
E
N
D
D
D
E
Site 20
Y242
A
E
K
V
Q
E
L
Y
A
P
R
E
V
Q
K
Site 21
S259
E
K
E
V
P
E
D
S
L
E
E
C
A
I
T
Site 22
T266
S
L
E
E
C
A
I
T
C
S
N
S
H
H
P
Site 23
Y280
P
C
E
S
N
Q
P
Y
G
N
T
R
I
T
F
Site 24
T286
P
Y
G
N
T
R
I
T
F
E
E
D
Q
V
D
Site 25
S294
F
E
E
D
Q
V
D
S
T
L
I
D
S
S
S
Site 26
T295
E
E
D
Q
V
D
S
T
L
I
D
S
S
S
H
Site 27
S301
S
T
L
I
D
S
S
S
H
D
E
W
L
D
A
Site 28
S329
E
E
E
K
G
P
V
S
P
R
N
L
Q
E
S
Site 29
S336
S
P
R
N
L
Q
E
S
E
E
E
E
A
P
Q
Site 30
T352
S
W
D
E
G
D
W
T
L
S
I
P
P
D
M
Site 31
S354
D
E
G
D
W
T
L
S
I
P
P
D
M
S
A
Site 32
S360
L
S
I
P
P
D
M
S
A
S
Y
Q
S
D
R
Site 33
S362
I
P
P
D
M
S
A
S
Y
Q
S
D
R
S
T
Site 34
Y363
P
P
D
M
S
A
S
Y
Q
S
D
R
S
T
F
Site 35
S365
D
M
S
A
S
Y
Q
S
D
R
S
T
F
H
S
Site 36
S368
A
S
Y
Q
S
D
R
S
T
F
H
S
V
E
E
Site 37
T369
S
Y
Q
S
D
R
S
T
F
H
S
V
E
E
Q
Site 38
S372
S
D
R
S
T
F
H
S
V
E
E
Q
Q
V
G
Site 39
S401
K
E
D
Q
E
A
T
S
P
R
L
S
R
E
L
Site 40
S405
E
A
T
S
P
R
L
S
R
E
L
L
D
E
K
Site 41
S420
E
P
E
V
L
Q
D
S
L
D
R
F
Y
S
T
Site 42
Y425
Q
D
S
L
D
R
F
Y
S
T
P
F
E
Y
L
Site 43
S426
D
S
L
D
R
F
Y
S
T
P
F
E
Y
L
E
Site 44
T427
S
L
D
R
F
Y
S
T
P
F
E
Y
L
E
L
Site 45
Y441
L
P
D
L
C
Q
P
Y
R
S
D
F
Y
S
L
Site 46
S443
D
L
C
Q
P
Y
R
S
D
F
Y
S
L
Q
E
Site 47
Y446
Q
P
Y
R
S
D
F
Y
S
L
Q
E
Q
H
L
Site 48
S447
P
Y
R
S
D
F
Y
S
L
Q
E
Q
H
L
G
Site 49
S480
G
P
P
C
P
R
L
S
R
E
L
P
E
V
V
Site 50
S495
E
P
E
D
L
Q
D
S
L
D
R
W
Y
S
T
Site 51
Y500
Q
D
S
L
D
R
W
Y
S
T
P
F
S
Y
P
Site 52
S501
D
S
L
D
R
W
Y
S
T
P
F
S
Y
P
E
Site 53
T502
S
L
D
R
W
Y
S
T
P
F
S
Y
P
E
L
Site 54
S505
R
W
Y
S
T
P
F
S
Y
P
E
L
P
D
S
Site 55
Y506
W
Y
S
T
P
F
S
Y
P
E
L
P
D
S
C
Site 56
S512
S
Y
P
E
L
P
D
S
C
Q
P
Y
G
S
C
Site 57
Y516
L
P
D
S
C
Q
P
Y
G
S
C
F
Y
S
L
Site 58
S518
D
S
C
Q
P
Y
G
S
C
F
Y
S
L
E
E
Site 59
S522
P
Y
G
S
C
F
Y
S
L
E
E
E
H
V
G
Site 60
S531
E
E
E
H
V
G
F
S
L
D
V
D
E
I
E
Site 61
Y540
D
V
D
E
I
E
K
Y
Q
E
G
E
E
D
Q
Site 62
S570
E
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 63
Y575
Q
D
S
L
D
R
C
Y
S
T
T
S
T
Y
F
Site 64
S576
D
S
L
D
R
C
Y
S
T
T
S
T
Y
F
Q
Site 65
T578
L
D
R
C
Y
S
T
T
S
T
Y
F
Q
L
H
Site 66
T580
R
C
Y
S
T
T
S
T
Y
F
Q
L
H
A
S
Site 67
Y581
C
Y
S
T
T
S
T
Y
F
Q
L
H
A
S
F
Site 68
S587
T
Y
F
Q
L
H
A
S
F
Q
Q
Y
R
S
A
Site 69
Y591
L
H
A
S
F
Q
Q
Y
R
S
A
F
Y
S
F
Site 70
S593
A
S
F
Q
Q
Y
R
S
A
F
Y
S
F
E
E
Site 71
S597
Q
Y
R
S
A
F
Y
S
F
E
E
Q
D
V
S
Site 72
S604
S
F
E
E
Q
D
V
S
L
A
L
D
V
D
N
Site 73
T615
D
V
D
N
R
F
F
T
L
T
V
I
R
H
H
Site 74
T617
D
N
R
F
F
T
L
T
V
I
R
H
H
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation