KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DKFZp434O194
Full Name:
Uncharacterized protein KIAA1683
Alias:
Type:
Mass (Da):
127693
Number AA:
1180
UniProt ID:
Q9H0B3
International Prot ID:
IPI00031282
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
L
Q
G
R
A
D
L
S
G
N
Q
G
N
A
A
Site 2
T29
T
V
H
E
P
V
V
T
Q
W
A
V
H
P
P
Site 3
S42
P
P
A
P
A
H
P
S
L
L
D
K
M
E
K
Site 4
S61
P
Q
H
E
G
L
K
S
K
E
H
L
P
Q
Q
Site 5
S76
P
A
E
G
K
T
A
S
R
R
V
P
R
L
R
Site 6
T108
M
M
H
A
R
A
A
T
L
I
Q
A
N
W
R
Site 7
Y117
I
Q
A
N
W
R
G
Y
W
L
R
Q
K
L
I
Site 8
S125
W
L
R
Q
K
L
I
S
Q
M
M
A
A
K
A
Site 9
S148
N
K
R
H
I
L
H
S
S
K
S
L
V
K
K
Site 10
S151
H
I
L
H
S
S
K
S
L
V
K
K
T
R
A
Site 11
Y165
A
E
E
G
D
I
P
Y
H
A
P
Q
Q
V
R
Site 12
S183
P
E
E
N
R
L
L
S
P
P
I
M
V
N
K
Site 13
S208
V
L
C
R
P
Q
S
S
P
L
L
Q
P
P
A
Site 14
T219
Q
P
P
A
A
Q
G
T
P
E
P
C
V
Q
G
Site 15
S252
I
R
F
P
C
P
V
S
L
D
A
K
C
Q
P
Site 16
T263
K
C
Q
P
C
L
L
T
R
T
I
R
S
T
C
Site 17
T281
I
E
G
D
S
V
K
T
K
R
V
S
A
R
T
Site 18
S285
S
V
K
T
K
R
V
S
A
R
T
N
K
A
R
Site 19
T296
N
K
A
R
A
P
E
T
P
L
S
R
R
Y
D
Site 20
S299
R
A
P
E
T
P
L
S
R
R
Y
D
Q
A
V
Site 21
Y302
E
T
P
L
S
R
R
Y
D
Q
A
V
T
R
P
Site 22
T307
R
R
Y
D
Q
A
V
T
R
P
S
R
A
Q
T
Site 23
S310
D
Q
A
V
T
R
P
S
R
A
Q
T
Q
G
P
Site 24
T314
T
R
P
S
R
A
Q
T
Q
G
P
V
K
A
E
Site 25
T322
Q
G
P
V
K
A
E
T
P
K
A
P
F
Q
I
Site 26
Y354
S
V
T
L
P
Q
T
Y
P
A
S
T
M
T
T
Site 27
S357
L
P
Q
T
Y
P
A
S
T
M
T
T
T
P
P
Site 28
T361
Y
P
A
S
T
M
T
T
T
P
P
K
T
S
P
Site 29
T362
P
A
S
T
M
T
T
T
P
P
K
T
S
P
V
Site 30
S367
T
T
T
P
P
K
T
S
P
V
P
K
V
T
I
Site 31
T377
P
K
V
T
I
I
K
T
P
A
Q
M
Y
P
G
Site 32
Y382
I
K
T
P
A
Q
M
Y
P
G
P
T
V
T
K
Site 33
T386
A
Q
M
Y
P
G
P
T
V
T
K
T
A
P
H
Site 34
T390
P
G
P
T
V
T
K
T
A
P
H
T
C
P
M
Site 35
T394
V
T
K
T
A
P
H
T
C
P
M
P
T
M
T
Site 36
T408
T
K
I
Q
V
H
P
T
A
S
R
T
G
T
P
Site 37
S410
I
Q
V
H
P
T
A
S
R
T
G
T
P
R
Q
Site 38
T412
V
H
P
T
A
S
R
T
G
T
P
R
Q
T
C
Site 39
T414
P
T
A
S
R
T
G
T
P
R
Q
T
C
P
A
Site 40
T418
R
T
G
T
P
R
Q
T
C
P
A
T
I
T
A
Site 41
T422
P
R
Q
T
C
P
A
T
I
T
A
K
N
R
P
Site 42
S432
A
K
N
R
P
Q
V
S
L
L
A
S
I
M
K
Site 43
T453
P
G
P
A
M
A
K
T
P
P
Q
M
H
P
V
Site 44
T461
P
P
Q
M
H
P
V
T
T
P
A
K
N
P
L
Site 45
T462
P
Q
M
H
P
V
T
T
P
A
K
N
P
L
Q
Site 46
S473
N
P
L
Q
T
C
L
S
A
T
M
S
K
T
S
Site 47
T475
L
Q
T
C
L
S
A
T
M
S
K
T
S
S
Q
Site 48
S477
T
C
L
S
A
T
M
S
K
T
S
S
Q
R
S
Site 49
T479
L
S
A
T
M
S
K
T
S
S
Q
R
S
P
V
Site 50
S480
S
A
T
M
S
K
T
S
S
Q
R
S
P
V
G
Site 51
S481
A
T
M
S
K
T
S
S
Q
R
S
P
V
G
V
Site 52
S484
S
K
T
S
S
Q
R
S
P
V
G
V
T
K
P
Site 53
S492
P
V
G
V
T
K
P
S
P
Q
T
R
L
P
A
Site 54
T502
T
R
L
P
A
M
I
T
K
T
P
A
Q
L
R
Site 55
T504
L
P
A
M
I
T
K
T
P
A
Q
L
R
S
V
Site 56
S510
K
T
P
A
Q
L
R
S
V
A
T
I
L
K
T
Site 57
T517
S
V
A
T
I
L
K
T
L
C
L
A
S
P
T
Site 58
S546
G
T
P
N
T
S
G
S
I
H
E
N
P
P
K
Site 59
T557
N
P
P
K
A
K
A
T
V
N
V
K
Q
A
A
Site 60
S571
A
K
V
V
K
A
S
S
P
S
Y
L
A
E
G
Site 61
Y574
V
K
A
S
S
P
S
Y
L
A
E
G
K
I
R
Site 62
T590
L
A
Q
P
H
P
G
T
G
V
P
R
A
A
A
Site 63
T608
L
E
A
E
K
I
K
T
G
T
Q
K
Q
A
K
Site 64
T616
G
T
Q
K
Q
A
K
T
D
M
A
F
K
T
S
Site 65
Y648
G
D
K
P
P
H
V
Y
V
P
V
D
M
A
V
Site 66
T667
G
Q
L
A
A
P
L
T
N
A
S
S
Q
R
H
Site 67
S671
A
P
L
T
N
A
S
S
Q
R
H
P
P
C
L
Site 68
S679
Q
R
H
P
P
C
L
S
Q
R
P
L
A
A
P
Site 69
T688
R
P
L
A
A
P
L
T
K
A
S
S
Q
G
H
Site 70
S692
A
P
L
T
K
A
S
S
Q
G
H
L
P
T
E
Site 71
T701
G
H
L
P
T
E
L
T
K
T
P
S
L
A
H
Site 72
T703
L
P
T
E
L
T
K
T
P
S
L
A
H
L
D
Site 73
S705
T
E
L
T
K
T
P
S
L
A
H
L
D
T
C
Site 74
T711
P
S
L
A
H
L
D
T
C
L
S
K
M
H
S
Site 75
S718
T
C
L
S
K
M
H
S
Q
T
H
L
A
T
G
Site 76
T740
A
P
L
A
T
C
L
T
K
T
Q
S
R
G
Q
Site 77
T742
L
A
T
C
L
T
K
T
Q
S
R
G
Q
P
I
Site 78
T750
Q
S
R
G
Q
P
I
T
D
I
T
T
C
L
I
Site 79
S766
A
H
Q
A
A
D
L
S
S
N
T
H
S
Q
V
Site 80
S767
H
Q
A
A
D
L
S
S
N
T
H
S
Q
V
L
Site 81
S771
D
L
S
S
N
T
H
S
Q
V
L
L
T
G
S
Site 82
T776
T
H
S
Q
V
L
L
T
G
S
K
V
S
N
H
Site 83
S778
S
Q
V
L
L
T
G
S
K
V
S
N
H
A
C
Site 84
S792
C
Q
R
L
G
G
L
S
A
P
P
W
A
K
P
Site 85
T804
A
K
P
E
D
R
Q
T
Q
P
Q
P
H
G
H
Site 86
T816
H
G
H
V
P
G
K
T
T
Q
G
G
P
C
P
Site 87
S860
G
A
T
R
A
Q
P
S
M
P
G
Q
A
V
P
Site 88
T900
R
G
A
A
S
W
D
T
W
R
N
K
A
V
V
Site 89
S912
A
V
V
P
P
R
R
S
G
E
P
M
V
S
M
Site 90
S918
R
S
G
E
P
M
V
S
M
Q
A
A
E
E
I
Site 91
Y940
I
Q
A
G
V
R
G
Y
L
A
R
R
R
I
R
Site 92
Y963
I
Q
A
T
W
R
G
Y
R
V
R
R
N
L
A
Site 93
T977
A
H
L
C
R
A
T
T
T
I
Q
S
A
W
R
Site 94
Y986
I
Q
S
A
W
R
G
Y
S
T
R
R
D
Q
A
Site 95
S987
Q
S
A
W
R
G
Y
S
T
R
R
D
Q
A
R
Site 96
T988
S
A
W
R
G
Y
S
T
R
R
D
Q
A
R
H
Site 97
S1015
G
S
R
A
G
V
M
S
D
R
S
W
F
Q
D
Site 98
S1018
A
G
V
M
S
D
R
S
W
F
Q
D
G
R
A
Site 99
T1027
F
Q
D
G
R
A
R
T
V
S
D
H
R
C
F
Site 100
S1029
D
G
R
A
R
T
V
S
D
H
R
C
F
Q
S
Site 101
S1047
H
A
C
S
V
C
H
S
L
S
S
R
I
G
S
Site 102
S1049
C
S
V
C
H
S
L
S
S
R
I
G
S
P
P
Site 103
S1050
S
V
C
H
S
L
S
S
R
I
G
S
P
P
S
Site 104
T1068
L
V
G
S
S
P
R
T
C
H
T
C
G
R
T
Site 105
T1071
S
S
P
R
T
C
H
T
C
G
R
T
Q
P
T
Site 106
S1095
T
E
G
P
G
A
V
S
W
A
S
A
Y
Q
L
Site 107
S1106
A
Y
Q
L
A
A
L
S
P
R
Q
P
H
R
Q
Site 108
S1169
L
L
G
P
A
D
P
S
A
S
S
R
H
M
H
Site 109
S1171
G
P
A
D
P
S
A
S
S
R
H
M
H
W
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation