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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRISPLD2
Full Name:
Cysteine-rich secretory protein LCCL domain-containing 2
Alias:
CRISP11; CRLD2; Cysteine-rich secretory protein 11; LCCL domain-containing cysteine-rich secretory protein 2; LCRISP2
Type:
Mass (Da):
55920
Number AA:
497
UniProt ID:
Q9H0B8
International Prot ID:
IPI00027821
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030133
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
T
L
L
E
E
L
L
S
K
Y
Q
H
N
E
S
Site 2
Y38
L
E
E
L
L
S
K
Y
Q
H
N
E
S
H
S
Site 3
S43
S
K
Y
Q
H
N
E
S
H
S
R
V
R
R
A
Site 4
Y79
P
Q
A
S
N
M
E
Y
M
T
W
D
D
E
L
Site 5
S89
W
D
D
E
L
E
K
S
A
A
A
W
A
S
Q
Site 6
Y121
L
G
A
H
W
G
R
Y
R
S
P
G
F
H
V
Site 7
S123
A
H
W
G
R
Y
R
S
P
G
F
H
V
Q
S
Site 8
S130
S
P
G
F
H
V
Q
S
W
Y
D
E
V
K
D
Site 9
Y132
G
F
H
V
Q
S
W
Y
D
E
V
K
D
Y
T
Site 10
Y138
W
Y
D
E
V
K
D
Y
T
Y
P
Y
P
S
E
Site 11
T139
Y
D
E
V
K
D
Y
T
Y
P
Y
P
S
E
C
Site 12
Y140
D
E
V
K
D
Y
T
Y
P
Y
P
S
E
C
N
Site 13
Y142
V
K
D
Y
T
Y
P
Y
P
S
E
C
N
P
W
Site 14
Y195
E
V
W
E
N
A
V
Y
F
V
C
N
Y
S
P
Site 15
Y212
N
W
I
G
E
A
P
Y
K
N
G
R
P
C
S
Site 16
S219
Y
K
N
G
R
P
C
S
E
C
P
P
S
Y
G
Site 17
S224
P
C
S
E
C
P
P
S
Y
G
G
S
C
R
N
Site 18
Y225
C
S
E
C
P
P
S
Y
G
G
S
C
R
N
N
Site 19
Y235
S
C
R
N
N
L
C
Y
R
E
E
T
Y
T
P
Site 20
T239
N
L
C
Y
R
E
E
T
Y
T
P
K
P
E
T
Site 21
T241
C
Y
R
E
E
T
Y
T
P
K
P
E
T
D
E
Site 22
T273
Q
P
R
V
M
R
P
T
K
P
K
K
T
S
A
Site 23
Y283
K
K
T
S
A
V
N
Y
M
T
Q
V
V
R
C
Site 24
T285
T
S
A
V
N
Y
M
T
Q
V
V
R
C
D
T
Site 25
T292
T
Q
V
V
R
C
D
T
K
M
K
D
R
C
K
Site 26
Y306
K
G
S
T
C
N
R
Y
Q
C
P
A
G
C
L
Site 27
T322
H
K
A
K
I
F
G
T
L
F
Y
E
S
S
S
Site 28
S328
G
T
L
F
Y
E
S
S
S
S
I
C
R
A
A
Site 29
T351
K
G
G
L
V
D
I
T
R
N
G
K
V
P
F
Site 30
S362
K
V
P
F
F
V
K
S
E
R
H
G
V
Q
S
Site 31
S369
S
E
R
H
G
V
Q
S
L
S
K
Y
K
P
S
Site 32
S371
R
H
G
V
Q
S
L
S
K
Y
K
P
S
S
S
Site 33
Y373
G
V
Q
S
L
S
K
Y
K
P
S
S
S
F
M
Site 34
S376
S
L
S
K
Y
K
P
S
S
S
F
M
V
S
K
Site 35
S377
L
S
K
Y
K
P
S
S
S
F
M
V
S
K
V
Site 36
S378
S
K
Y
K
P
S
S
S
F
M
V
S
K
V
K
Site 37
S382
P
S
S
S
F
M
V
S
K
V
K
V
Q
D
L
Site 38
Y423
H
C
K
D
E
P
S
Y
W
A
P
V
F
G
T
Site 39
T467
M
P
V
D
K
K
K
T
Y
V
G
S
L
R
N
Site 40
Y468
P
V
D
K
K
K
T
Y
V
G
S
L
R
N
G
Site 41
S471
K
K
K
T
Y
V
G
S
L
R
N
G
V
Q
S
Site 42
S478
S
L
R
N
G
V
Q
S
E
S
L
G
T
P
R
Site 43
S480
R
N
G
V
Q
S
E
S
L
G
T
P
R
D
G
Site 44
T483
V
Q
S
E
S
L
G
T
P
R
D
G
K
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation