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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM117
Full Name:
Transmembrane protein 117
Alias:
Type:
Mass (Da):
60185
Number AA:
514
UniProt ID:
Q9H0C3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
I
F
A
E
D
P
V
S
H
S
Q
T
E
A
N
Site 2
S38
A
E
D
P
V
S
H
S
Q
T
E
A
N
V
I
Site 3
T40
D
P
V
S
H
S
Q
T
E
A
N
V
I
V
V
Site 4
Y58
F
S
F
V
T
N
K
Y
P
R
G
V
G
W
R
Site 5
Y144
G
A
Y
I
I
T
D
Y
M
G
I
R
N
E
S
Site 6
Y181
M
M
L
Q
D
K
P
Y
P
D
W
G
K
S
A
Site 7
S234
L
N
R
G
F
L
P
S
D
E
V
S
R
A
F
Site 8
T276
V
N
L
P
G
L
H
T
P
H
M
Q
F
K
I
Site 9
Y294
Q
K
I
F
K
E
E
Y
R
I
H
I
T
G
K
Site 10
Y330
I
F
Y
K
P
H
E
Y
G
Q
Y
I
G
P
G
Site 11
Y333
K
P
H
E
Y
G
Q
Y
I
G
P
G
Q
K
I
Site 12
Y341
I
G
P
G
Q
K
I
Y
T
V
K
D
S
E
S
Site 13
T342
G
P
G
Q
K
I
Y
T
V
K
D
S
E
S
L
Site 14
S348
Y
T
V
K
D
S
E
S
L
K
D
L
N
R
T
Site 15
Y374
N
P
R
T
N
K
T
Y
V
E
G
D
M
F
L
Site 16
T430
R
M
E
N
Q
D
K
T
Y
T
R
M
K
R
K
Site 17
Y431
M
E
N
Q
D
K
T
Y
T
R
M
K
R
K
S
Site 18
S438
Y
T
R
M
K
R
K
S
P
S
E
H
S
K
D
Site 19
S440
R
M
K
R
K
S
P
S
E
H
S
K
D
M
G
Site 20
T453
M
G
I
T
R
E
N
T
Q
A
S
V
E
D
P
Site 21
S456
T
R
E
N
T
Q
A
S
V
E
D
P
L
N
D
Site 22
S465
E
D
P
L
N
D
P
S
L
V
C
I
R
S
D
Site 23
Y478
S
D
F
N
E
I
V
Y
K
S
S
H
L
T
S
Site 24
S480
F
N
E
I
V
Y
K
S
S
H
L
T
S
E
N
Site 25
T484
V
Y
K
S
S
H
L
T
S
E
N
L
S
S
Q
Site 26
S485
Y
K
S
S
H
L
T
S
E
N
L
S
S
Q
L
Site 27
S489
H
L
T
S
E
N
L
S
S
Q
L
N
E
S
T
Site 28
S490
L
T
S
E
N
L
S
S
Q
L
N
E
S
T
S
Site 29
S495
L
S
S
Q
L
N
E
S
T
S
A
T
E
A
D
Site 30
S497
S
Q
L
N
E
S
T
S
A
T
E
A
D
Q
D
Site 31
T499
L
N
E
S
T
S
A
T
E
A
D
Q
D
P
T
Site 32
T506
T
E
A
D
Q
D
P
T
T
S
K
S
T
P
T
Site 33
T507
E
A
D
Q
D
P
T
T
S
K
S
T
P
T
N
Site 34
S508
A
D
Q
D
P
T
T
S
K
S
T
P
T
N
_
Site 35
S510
Q
D
P
T
T
S
K
S
T
P
T
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation