PhosphoNET

           
Protein Info 
   
Short Name:  SHARPIN
Full Name:  Sharpin
Alias:  DKFZP434N1923; PSEC0216; Shank-associated RH domain interactor; Shank-associated RH domain-interacting protein; Shank-interacting protein-like 1; Shrpn; SIPL1
Type: 
Mass (Da):  39949
Number AA:  387
UniProt ID:  Q9H0F6
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0008270     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S47QLRRLQLSADPERPG
Site 2S76NLEWPLESVSYTIRG
Site 3S78EWPLESVSYTIRGPT
Site 4Y79WPLESVSYTIRGPTQ
Site 5T80PLESVSYTIRGPTQH
Site 6T85SYTIRGPTQHELQPP
Site 7T98PPPGGPGTLSLHFLN
Site 8S100PGGPGTLSLHFLNPQ
Site 9T120AVLVRGATVEGQNGS
Site 10S127TVEGQNGSKSNSPPA
Site 11S129EGQNGSKSNSPPALG
Site 12S131QNGSKSNSPPALGPE
Site 13S143GPEACPVSLPSPPEA
Site 14S151LPSPPEASTLKGPPP
Site 15T152PSPPEASTLKGPPPE
Site 16S165PEADLPRSPGNLTER
Site 17T170PRSPGNLTEREELAG
Site 18S178EREELAGSLARAIAG
Site 19S233EDAASAASAASSAHV
Site 20T249LQVHPHCTVAALQEQ
Site 21Y286PERSLASYGVRQDGD
Site 22Y298DGDPAFLYLLSAPRE
Site 23T309APREAPATGPSPQHP
Site 24S312EAPATGPSPQHPQKM
Site 25S342PGPQPAASSLPSPLQ
Site 26S343GPQPAASSLPSPLQP
Site 27S346PAASSLPSPLQPSWS
Site 28S351LPSPLQPSWSCPSCT
Site 29S353SPLQPSWSCPSCTFI
Site 30T378CSTQRPCTWDPLAAA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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