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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PUS7L
Full Name:
Pseudouridylate synthase 7 homolog-like protein
Alias:
DKFZP434G1415; pseudouridylate synthase 7-like
Type:
EC 5.4.99.-; Isomerase; RNA processing
Mass (Da):
80682
Number AA:
701
UniProt ID:
Q9H0K6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0009982
PhosphoSite+
KinaseNET
Biological Process:
GO:0001522
GO:0008033
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
E
E
D
T
D
Y
R
I
R
F
S
Site 2
Y7
_
M
E
E
D
T
D
Y
R
I
R
F
S
S
L
Site 3
T26
D
H
V
G
F
H
G
T
I
K
S
S
P
S
D
Site 4
S29
G
F
H
G
T
I
K
S
S
P
S
D
F
I
V
Site 5
S79
K
L
D
L
Q
N
L
S
L
E
D
G
R
N
Q
Site 6
Y94
E
V
H
T
L
I
K
Y
T
D
G
D
Q
N
H
Site 7
S103
D
G
D
Q
N
H
Q
S
G
S
E
K
E
D
T
Site 8
S105
D
Q
N
H
Q
S
G
S
E
K
E
D
T
I
V
Site 9
T110
S
G
S
E
K
E
D
T
I
V
D
G
T
S
K
Site 10
T115
E
D
T
I
V
D
G
T
S
K
C
E
E
K
A
Site 11
S127
E
K
A
D
V
L
S
S
F
L
D
E
K
T
H
Site 12
T133
S
S
F
L
D
E
K
T
H
E
L
L
N
N
F
Site 13
S150
D
V
R
E
K
W
L
S
K
T
E
L
I
G
L
Site 14
T152
R
E
K
W
L
S
K
T
E
L
I
G
L
P
P
Site 15
S174
L
D
K
N
Q
R
A
S
L
H
S
A
I
R
Q
Site 16
S177
N
Q
R
A
S
L
H
S
A
I
R
Q
K
F
P
Site 17
T188
Q
K
F
P
F
L
V
T
V
G
K
N
S
E
I
Site 18
S211
K
E
L
C
H
L
V
S
E
E
E
A
F
D
F
Site 19
Y221
E
A
F
D
F
F
K
Y
L
D
A
K
K
E
N
Site 20
T232
K
K
E
N
S
K
F
T
F
K
P
D
T
N
K
Site 21
T237
K
F
T
F
K
P
D
T
N
K
D
H
R
K
A
Site 22
T259
K
F
G
N
L
V
E
T
K
S
F
S
K
M
N
Site 23
S261
G
N
L
V
E
T
K
S
F
S
K
M
N
C
S
Site 24
S263
L
V
E
T
K
S
F
S
K
M
N
C
S
A
G
Site 25
S268
S
F
S
K
M
N
C
S
A
G
N
P
N
V
V
Site 26
T277
G
N
P
N
V
V
V
T
V
R
F
R
E
K
A
Site 27
S293
K
R
G
K
R
P
L
S
E
C
Q
E
G
K
V
Site 28
S333
G
V
I
P
S
D
F
S
Y
A
G
L
K
D
K
Site 29
Y334
V
I
P
S
D
F
S
Y
A
G
L
K
D
K
K
Site 30
T354
A
M
V
V
R
K
V
T
P
E
R
L
K
N
I
Site 31
S377
M
N
V
F
N
I
R
S
V
D
D
S
L
R
L
Site 32
S381
N
I
R
S
V
D
D
S
L
R
L
G
Q
L
K
Site 33
Y428
K
K
K
G
F
V
N
Y
Y
G
P
Q
R
F
G
Site 34
Y429
K
K
G
F
V
N
Y
Y
G
P
Q
R
F
G
K
Site 35
T463
K
A
I
K
L
F
L
T
P
E
D
L
D
D
P
Site 36
Y477
P
V
N
R
A
K
K
Y
F
L
Q
T
E
D
A
Site 37
S489
E
D
A
K
G
T
L
S
L
M
P
E
F
K
V
Site 38
Y530
P
H
S
M
R
I
F
Y
V
H
A
Y
T
S
K
Site 39
Y534
R
I
F
Y
V
H
A
Y
T
S
K
I
W
N
E
Site 40
Y545
I
W
N
E
A
V
S
Y
R
L
E
T
Y
G
A
Site 41
T549
A
V
S
Y
R
L
E
T
Y
G
A
R
V
V
Q
Site 42
S574
D
D
E
N
F
P
N
S
K
I
H
L
V
T
E
Site 43
Y605
V
L
G
Y
N
I
Q
Y
P
K
N
K
V
G
Q
Site 44
Y614
K
N
K
V
G
Q
W
Y
H
D
I
L
S
R
D
Site 45
T625
L
S
R
D
G
L
Q
T
C
R
F
K
V
P
T
Site 46
Y653
K
H
P
C
N
L
S
Y
Q
L
M
E
D
H
D
Site 47
T665
D
H
D
I
D
V
K
T
K
G
S
H
I
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation