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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MUDENG
Full Name:
MHD domain-containing death-inducing protein
Alias:
Mu-2-related death-inducing protein;Putative HIV-1 infection-related protein
Type:
Mass (Da):
54767
Number AA:
490
UniProt ID:
Q9H0R1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Q
R
A
V
W
L
I
S
H
E
P
G
T
P
L
Site 2
T20
P
G
T
P
L
C
G
T
V
R
F
S
R
R
Y
Site 3
S24
L
C
G
T
V
R
F
S
R
R
Y
P
T
V
E
Site 4
Y27
T
V
R
F
S
R
R
Y
P
T
V
E
K
R
A
Site 5
T29
R
F
S
R
R
Y
P
T
V
E
K
R
A
R
V
Site 6
S41
A
R
V
F
N
G
A
S
Y
V
P
V
P
E
D
Site 7
Y42
R
V
F
N
G
A
S
Y
V
P
V
P
E
D
G
Site 8
S71
D
D
K
D
F
V
E
S
R
D
S
C
S
R
I
Site 9
S74
D
F
V
E
S
R
D
S
C
S
R
I
N
K
T
Site 10
S76
V
E
S
R
D
S
C
S
R
I
N
K
T
S
I
Site 11
S117
P
L
V
E
Q
T
L
S
P
R
P
P
L
I
S
Site 12
S124
S
P
R
P
P
L
I
S
V
S
G
V
S
Q
G
Site 13
S126
R
P
P
L
I
S
V
S
G
V
S
Q
G
F
E
Site 14
Y143
F
G
I
Q
D
F
L
Y
S
G
Q
K
N
D
S
Site 15
S144
G
I
Q
D
F
L
Y
S
G
Q
K
N
D
S
E
Site 16
S150
Y
S
G
Q
K
N
D
S
E
L
N
T
K
L
S
Site 17
T154
K
N
D
S
E
L
N
T
K
L
S
Q
L
P
D
Site 18
S157
S
E
L
N
T
K
L
S
Q
L
P
D
L
L
L
Site 19
S180
L
D
A
N
L
Q
N
S
L
D
N
T
N
F
A
Site 20
T184
L
Q
N
S
L
D
N
T
N
F
A
S
V
T
Q
Site 21
S188
L
D
N
T
N
F
A
S
V
T
Q
P
Q
K
Q
Site 22
Y203
P
A
W
K
T
G
T
Y
K
G
K
P
Q
V
S
Site 23
S212
G
K
P
Q
V
S
I
S
I
T
E
K
V
K
S
Site 24
T214
P
Q
V
S
I
S
I
T
E
K
V
K
S
M
Q
Site 25
S219
S
I
T
E
K
V
K
S
M
Q
Y
D
K
Q
G
Site 26
Y222
E
K
V
K
S
M
Q
Y
D
K
Q
G
I
A
D
Site 27
T230
D
K
Q
G
I
A
D
T
W
Q
V
V
G
T
V
Site 28
S255
P
N
V
T
I
S
L
S
L
P
T
N
G
S
P
Site 29
S284
S
A
I
L
T
S
S
S
I
D
A
M
D
D
S
Site 30
S291
S
I
D
A
M
D
D
S
A
F
S
G
P
Y
K
Site 31
S294
A
M
D
D
S
A
F
S
G
P
Y
K
F
P
F
Site 32
Y297
D
S
A
F
S
G
P
Y
K
F
P
F
T
P
P
Site 33
T302
G
P
Y
K
F
P
F
T
P
P
L
E
S
F
N
Site 34
Y326
V
P
P
I
L
G
F
Y
Q
M
K
E
E
E
V
Site 35
T338
E
E
V
Q
L
R
I
T
I
N
L
K
L
H
E
Site 36
Y361
C
E
A
H
I
P
F
Y
N
R
G
P
I
T
H
Site 37
Y371
G
P
I
T
H
L
E
Y
K
T
S
F
G
Q
L
Site 38
S374
T
H
L
E
Y
K
T
S
F
G
Q
L
E
V
F
Site 39
S398
I
G
Q
K
F
P
K
S
M
E
I
S
L
S
G
Site 40
T408
I
S
L
S
G
T
V
T
F
G
A
K
S
H
E
Site 41
S413
T
V
T
F
G
A
K
S
H
E
K
Q
P
F
D
Site 42
T440
H
F
R
I
L
D
Y
T
L
T
G
C
Y
A
D
Site 43
T442
R
I
L
D
Y
T
L
T
G
C
Y
A
D
Q
H
Site 44
S456
H
S
V
Q
V
F
A
S
G
K
P
K
I
S
A
Site 45
S462
A
S
G
K
P
K
I
S
A
H
R
K
L
I
S
Site 46
Y472
R
K
L
I
S
S
D
Y
Y
I
W
N
S
K
A
Site 47
Y473
K
L
I
S
S
D
Y
Y
I
W
N
S
K
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation