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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GBP3
Full Name:
Guanylate-binding protein 3
Alias:
GTP-binding protein 3;Guanine nucleotide-binding protein 3
Type:
Mass (Da):
68114
Number AA:
595
UniProt ID:
Q9H0R5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
G
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
Site 2
Y53
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
G
Site 3
S66
A
G
K
N
K
G
F
S
L
G
S
T
V
K
S
Site 4
S69
N
K
G
F
S
L
G
S
T
V
K
S
H
T
K
Site 5
T70
K
G
F
S
L
G
S
T
V
K
S
H
T
K
G
Site 6
S73
S
L
G
S
T
V
K
S
H
T
K
G
I
W
M
Site 7
Y128
L
L
S
S
T
L
V
Y
N
S
M
G
T
I
N
Site 8
S130
S
S
T
L
V
Y
N
S
M
G
T
I
N
Q
Q
Site 9
Y143
Q
Q
A
M
D
Q
L
Y
Y
V
T
E
L
T
H
Site 10
Y144
Q
A
M
D
Q
L
Y
Y
V
T
E
L
T
H
R
Site 11
T149
L
Y
Y
V
T
E
L
T
H
R
I
R
S
K
S
Site 12
S154
E
L
T
H
R
I
R
S
K
S
S
P
D
E
N
Site 13
S156
T
H
R
I
R
S
K
S
S
P
D
E
N
E
N
Site 14
S157
H
R
I
R
S
K
S
S
P
D
E
N
E
N
E
Site 15
S166
D
E
N
E
N
E
D
S
A
D
F
V
S
F
F
Site 16
S184
V
W
T
L
R
D
F
S
L
D
L
E
A
D
G
Site 17
T195
E
A
D
G
Q
P
L
T
P
D
E
Y
L
E
Y
Site 18
Y199
Q
P
L
T
P
D
E
Y
L
E
Y
S
L
K
L
Site 19
Y202
T
P
D
E
Y
L
E
Y
S
L
K
L
T
Q
G
Site 20
S203
P
D
E
Y
L
E
Y
S
L
K
L
T
Q
G
T
Site 21
T207
L
E
Y
S
L
K
L
T
Q
G
T
S
Q
K
D
Site 22
S211
L
K
L
T
Q
G
T
S
Q
K
D
K
N
F
N
Site 23
S273
D
F
C
S
Y
I
F
S
N
S
K
T
K
T
L
Site 24
S275
C
S
Y
I
F
S
N
S
K
T
K
T
L
S
G
Site 25
T277
Y
I
F
S
N
S
K
T
K
T
L
S
G
G
I
Site 26
T279
F
S
N
S
K
T
K
T
L
S
G
G
I
K
V
Site 27
S281
N
S
K
T
K
T
L
S
G
G
I
K
V
N
G
Site 28
Y298
L
E
S
L
V
L
T
Y
I
N
A
I
S
R
G
Site 29
S303
L
T
Y
I
N
A
I
S
R
G
D
L
P
C
M
Site 30
Y333
V
Q
K
A
I
A
H
Y
D
Q
Q
M
G
Q
K
Site 31
S358
L
L
D
L
H
R
V
S
E
R
E
A
T
E
V
Site 32
T363
R
V
S
E
R
E
A
T
E
V
Y
M
K
N
S
Site 33
Y366
E
R
E
A
T
E
V
Y
M
K
N
S
F
K
D
Site 34
S401
C
K
Q
N
Q
E
A
S
S
D
R
C
S
A
L
Site 35
S402
K
Q
N
Q
E
A
S
S
D
R
C
S
A
L
L
Site 36
Y425
E
E
V
K
A
G
I
Y
S
K
P
G
G
Y
C
Site 37
Y445
L
Q
D
L
E
K
K
Y
Y
E
E
P
R
K
G
Site 38
Y446
Q
D
L
E
K
K
Y
Y
E
E
P
R
K
G
I
Site 39
T461
Q
A
E
E
I
L
Q
T
Y
L
K
S
K
E
S
Site 40
Y462
A
E
E
I
L
Q
T
Y
L
K
S
K
E
S
V
Site 41
S465
I
L
Q
T
Y
L
K
S
K
E
S
V
T
D
A
Site 42
S468
T
Y
L
K
S
K
E
S
V
T
D
A
I
L
Q
Site 43
S496
V
E
C
V
K
A
E
S
A
Q
A
S
A
K
M
Site 44
S500
K
A
E
S
A
Q
A
S
A
K
M
V
E
E
M
Site 45
Y511
V
E
E
M
Q
I
K
Y
Q
Q
M
M
E
E
K
Site 46
S521
M
M
E
E
K
E
K
S
Y
Q
E
H
V
K
Q
Site 47
T547
L
L
E
E
Q
E
K
T
L
T
S
K
L
Q
E
Site 48
T549
E
E
Q
E
K
T
L
T
S
K
L
Q
E
Q
A
Site 49
S550
E
Q
E
K
T
L
T
S
K
L
Q
E
Q
A
R
Site 50
S567
K
E
R
C
Q
G
E
S
T
Q
L
Q
N
E
I
Site 51
T580
E
I
Q
K
L
Q
K
T
L
K
K
K
T
K
R
Site 52
T585
Q
K
T
L
K
K
K
T
K
R
Y
M
S
H
K
Site 53
Y588
L
K
K
K
T
K
R
Y
M
S
H
K
L
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation