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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM168
Full Name:
Transmembrane protein 168
Alias:
Type:
Mass (Da):
79755
Number AA:
697
UniProt ID:
Q9H0V1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
N
R
E
V
N
M
H
S
S
V
R
Y
L
G
Y
Site 2
S32
R
E
V
N
M
H
S
S
V
R
Y
L
G
Y
L
Site 3
S113
L
C
F
L
D
N
S
S
F
K
N
D
V
K
E
Site 4
Y125
V
K
E
E
S
T
K
Y
L
L
L
T
S
I
V
Site 5
S144
C
S
L
V
E
R
I
S
G
Y
V
R
H
R
P
Site 6
Y146
L
V
E
R
I
S
G
Y
V
R
H
R
P
T
L
Site 7
T152
G
Y
V
R
H
R
P
T
L
L
T
T
V
E
F
Site 8
T155
R
H
R
P
T
L
L
T
T
V
E
F
L
E
L
Site 9
S198
I
I
D
L
R
M
K
S
F
L
A
I
P
N
L
Site 10
S247
D
I
Y
F
S
G
L
S
V
T
E
R
W
K
P
Site 11
T249
Y
F
S
G
L
S
V
T
E
R
W
K
P
F
L
Site 12
Y257
E
R
W
K
P
F
L
Y
R
G
R
I
C
R
R
Site 13
T276
F
A
G
M
I
E
L
T
F
F
I
L
S
A
F
Site 14
S281
E
L
T
F
F
I
L
S
A
F
K
L
R
D
T
Site 15
Y330
L
N
D
C
H
K
V
Y
F
T
H
R
T
D
Y
Site 16
T332
D
C
H
K
V
Y
F
T
H
R
T
D
Y
N
S
Site 17
T335
K
V
Y
F
T
H
R
T
D
Y
N
S
L
D
R
Site 18
Y337
Y
F
T
H
R
T
D
Y
N
S
L
D
R
I
M
Site 19
S339
T
H
R
T
D
Y
N
S
L
D
R
I
M
A
S
Site 20
S346
S
L
D
R
I
M
A
S
K
G
M
R
H
F
C
Site 21
S424
V
I
P
T
N
F
C
S
P
D
G
Q
P
T
L
Site 22
T430
C
S
P
D
G
Q
P
T
L
L
P
P
E
H
V
Site 23
T445
Q
E
L
N
L
R
S
T
G
M
L
N
A
I
Q
Site 24
Y463
A
Y
H
M
I
E
T
Y
G
C
D
Y
S
T
S
Site 25
Y467
I
E
T
Y
G
C
D
Y
S
T
S
G
L
S
F
Site 26
S468
E
T
Y
G
C
D
Y
S
T
S
G
L
S
F
D
Site 27
T469
T
Y
G
C
D
Y
S
T
S
G
L
S
F
D
T
Site 28
S470
Y
G
C
D
Y
S
T
S
G
L
S
F
D
T
L
Site 29
S473
D
Y
S
T
S
G
L
S
F
D
T
L
H
S
K
Site 30
T476
T
S
G
L
S
F
D
T
L
H
S
K
L
K
A
Site 31
T489
K
A
F
L
E
L
R
T
V
D
G
P
R
H
D
Site 32
T497
V
D
G
P
R
H
D
T
Y
I
L
Y
Y
S
G
Site 33
Y498
D
G
P
R
H
D
T
Y
I
L
Y
Y
S
G
H
Site 34
Y501
R
H
D
T
Y
I
L
Y
Y
S
G
H
T
H
G
Site 35
T524
G
D
T
L
R
L
D
T
L
I
E
W
W
R
E
Site 36
T550
V
L
D
S
E
N
S
T
P
W
V
K
E
V
R
Site 37
Y563
V
R
K
I
N
D
Q
Y
I
A
V
Q
G
A
E
Site 38
T574
Q
G
A
E
L
I
K
T
V
D
I
E
E
A
D
Site 39
Y595
F
T
K
D
W
V
E
Y
N
C
N
S
S
N
N
Site 40
T606
S
S
N
N
I
C
W
T
E
K
G
R
T
V
K
Site 41
T611
C
W
T
E
K
G
R
T
V
K
A
V
Y
G
V
Site 42
S623
Y
G
V
S
K
R
W
S
D
Y
T
L
H
L
P
Site 43
Y625
V
S
K
R
W
S
D
Y
T
L
H
L
P
T
G
Site 44
T626
S
K
R
W
S
D
Y
T
L
H
L
P
T
G
S
Site 45
T631
D
Y
T
L
H
L
P
T
G
S
D
V
A
K
H
Site 46
S633
T
L
H
L
P
T
G
S
D
V
A
K
H
W
M
Site 47
S679
C
L
K
R
L
K
M
S
W
F
L
P
T
V
L
Site 48
T684
K
M
S
W
F
L
P
T
V
L
D
T
G
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation