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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Bcl-11A
Full Name:
B-cell lymphoma/leukemia 11A
Alias:
BC11A; B-cell CLL/lymphoma 11A; BCL11A; BCL11A-L; BCL11A-S; BCL11A-XL; COUP-TF-interacting protein 1; CTIP1; Ecotropic viral integration site 9 protein homolog; EVI9; FLJ10173; HBFQTL5; KIAA1809; ZNF856
Type:
Transcription factor; Nuclear receptor co-regulator
Mass (Da):
91197
Number AA:
835
UniProt ID:
Q9H165
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
Q
G
K
P
Q
H
L
S
K
R
E
F
S
P
E
Site 2
S18
H
L
S
K
R
E
F
S
P
E
P
L
E
A
I
Site 3
T27
E
P
L
E
A
I
L
T
D
D
E
P
D
H
G
Site 4
S86
K
A
V
D
K
P
P
S
P
S
P
I
E
M
K
Site 5
S88
V
D
K
P
P
S
P
S
P
I
E
M
K
K
A
Site 6
T106
V
E
V
G
I
Q
V
T
P
E
D
D
D
C
L
Site 7
S114
P
E
D
D
D
C
L
S
T
S
S
R
G
I
C
Site 8
T115
E
D
D
D
C
L
S
T
S
S
R
G
I
C
P
Site 9
S116
D
D
D
C
L
S
T
S
S
R
G
I
C
P
K
Site 10
S138
L
L
H
W
R
G
L
S
S
P
R
S
A
H
G
Site 11
S139
L
H
W
R
G
L
S
S
P
R
S
A
H
G
A
Site 12
S142
R
G
L
S
S
P
R
S
A
H
G
A
L
I
P
Site 13
Y157
T
P
G
M
S
A
E
Y
A
P
Q
G
I
C
K
Site 14
Y170
C
K
D
E
P
S
S
Y
T
C
T
T
C
K
Q
Site 15
T173
E
P
S
S
Y
T
C
T
T
C
K
Q
P
F
T
Site 16
Y198
N
T
H
G
L
R
I
Y
L
E
S
E
H
G
S
Site 17
S201
G
L
R
I
Y
L
E
S
E
H
G
S
P
L
T
Site 18
S205
Y
L
E
S
E
H
G
S
P
L
T
P
R
V
G
Site 19
T208
S
E
H
G
S
P
L
T
P
R
V
G
I
P
S
Site 20
S215
T
P
R
V
G
I
P
S
G
L
G
A
E
C
P
Site 21
S223
G
L
G
A
E
C
P
S
Q
P
P
L
H
G
I
Site 22
S246
N
L
L
R
I
P
G
S
V
S
R
E
A
S
G
Site 23
S248
L
R
I
P
G
S
V
S
R
E
A
S
G
L
A
Site 24
S252
G
S
V
S
R
E
A
S
G
L
A
E
G
R
F
Site 25
T262
A
E
G
R
F
P
P
T
P
P
L
F
S
P
P
Site 26
S267
P
P
T
P
P
L
F
S
P
P
P
R
H
H
L
Site 27
T291
A
E
E
M
A
L
A
T
H
H
P
S
A
F
D
Site 28
S316
E
P
P
A
M
D
F
S
R
R
L
R
E
L
A
Site 29
T326
L
R
E
L
A
G
N
T
S
S
P
P
L
S
P
Site 30
S327
R
E
L
A
G
N
T
S
S
P
P
L
S
P
G
Site 31
S328
E
L
A
G
N
T
S
S
P
P
L
S
P
G
R
Site 32
S332
N
T
S
S
P
P
L
S
P
G
R
P
S
P
M
Site 33
S337
P
L
S
P
G
R
P
S
P
M
Q
R
L
L
Q
Site 34
S350
L
Q
P
F
Q
P
G
S
K
P
P
F
L
A
T
Site 35
T357
S
K
P
P
F
L
A
T
P
P
L
P
P
L
Q
Site 36
S365
P
P
L
P
P
L
Q
S
A
P
P
P
S
Q
P
Site 37
S370
L
Q
S
A
P
P
P
S
Q
P
P
V
K
S
K
Site 38
S376
P
S
Q
P
P
V
K
S
K
S
C
E
F
C
G
Site 39
S378
Q
P
P
V
K
S
K
S
C
E
F
C
G
K
T
Site 40
S390
G
K
T
F
K
F
Q
S
N
L
V
V
H
R
R
Site 41
S398
N
L
V
V
H
R
R
S
H
T
G
E
K
P
Y
Site 42
T400
V
V
H
R
R
S
H
T
G
E
K
P
Y
K
C
Site 43
T426
K
L
K
R
H
M
K
T
H
M
H
K
S
S
P
Site 44
S431
M
K
T
H
M
H
K
S
S
P
M
T
V
K
S
Site 45
S432
K
T
H
M
H
K
S
S
P
M
T
V
K
S
D
Site 46
T435
M
H
K
S
S
P
M
T
V
K
S
D
D
G
L
Site 47
S438
S
S
P
M
T
V
K
S
D
D
G
L
S
T
A
Site 48
S443
V
K
S
D
D
G
L
S
T
A
S
S
P
E
P
Site 49
S446
D
D
G
L
S
T
A
S
S
P
E
P
G
T
S
Site 50
S447
D
G
L
S
T
A
S
S
P
E
P
G
T
S
D
Site 51
S453
S
S
P
E
P
G
T
S
D
L
V
G
S
A
S
Site 52
S458
G
T
S
D
L
V
G
S
A
S
S
A
L
K
S
Site 53
S472
S
V
V
A
K
F
K
S
E
N
D
P
N
L
I
Site 54
T506
E
E
E
E
E
E
L
T
E
S
E
R
V
D
Y
Site 55
S508
E
E
E
E
L
T
E
S
E
R
V
D
Y
G
F
Site 56
Y513
T
E
S
E
R
V
D
Y
G
F
G
L
S
L
E
Site 57
S518
V
D
Y
G
F
G
L
S
L
E
A
A
R
H
H
Site 58
S528
A
A
R
H
H
E
N
S
S
R
G
A
V
V
G
Site 59
T584
E
A
E
G
H
R
D
T
C
D
E
D
S
V
A
Site 60
S589
R
D
T
C
D
E
D
S
V
A
G
E
S
D
R
Site 61
S594
E
D
S
V
A
G
E
S
D
R
I
D
D
G
T
Site 62
T601
S
D
R
I
D
D
G
T
V
N
G
R
G
C
S
Site 63
S608
T
V
N
G
R
G
C
S
P
G
E
S
A
S
G
Site 64
S612
R
G
C
S
P
G
E
S
A
S
G
G
L
S
K
Site 65
S614
C
S
P
G
E
S
A
S
G
G
L
S
K
K
L
Site 66
S618
E
S
A
S
G
G
L
S
K
K
L
L
L
G
S
Site 67
S625
S
K
K
L
L
L
G
S
P
S
S
L
S
P
F
Site 68
S627
K
L
L
L
G
S
P
S
S
L
S
P
F
S
K
Site 69
S628
L
L
L
G
S
P
S
S
L
S
P
F
S
K
R
Site 70
S630
L
G
S
P
S
S
L
S
P
F
S
K
R
I
K
Site 71
S633
P
S
S
L
S
P
F
S
K
R
I
K
L
E
K
Site 72
T652
P
P
A
A
M
P
N
T
E
N
V
Y
S
Q
W
Site 73
S675
Q
L
K
D
P
F
L
S
F
G
D
S
R
Q
S
Site 74
S679
P
F
L
S
F
G
D
S
R
Q
S
P
F
A
S
Site 75
S682
S
F
G
D
S
R
Q
S
P
F
A
S
S
S
E
Site 76
S686
S
R
Q
S
P
F
A
S
S
S
E
H
S
S
E
Site 77
S687
R
Q
S
P
F
A
S
S
S
E
H
S
S
E
N
Site 78
S688
Q
S
P
F
A
S
S
S
E
H
S
S
E
N
G
Site 79
S691
F
A
S
S
S
E
H
S
S
E
N
G
S
L
R
Site 80
S692
A
S
S
S
E
H
S
S
E
N
G
S
L
R
F
Site 81
S696
E
H
S
S
E
N
G
S
L
R
F
S
T
P
P
Site 82
S700
E
N
G
S
L
R
F
S
T
P
P
G
E
L
D
Site 83
T701
N
G
S
L
R
F
S
T
P
P
G
E
L
D
G
Site 84
S711
G
E
L
D
G
G
I
S
G
R
S
G
T
G
S
Site 85
S714
D
G
G
I
S
G
R
S
G
T
G
S
G
G
S
Site 86
T716
G
I
S
G
R
S
G
T
G
S
G
G
S
T
P
Site 87
S718
S
G
R
S
G
T
G
S
G
G
S
T
P
H
I
Site 88
S721
S
G
T
G
S
G
G
S
T
P
H
I
S
G
P
Site 89
T722
G
T
G
S
G
G
S
T
P
H
I
S
G
P
G
Site 90
S726
G
G
S
T
P
H
I
S
G
P
G
P
G
R
P
Site 91
S734
G
P
G
P
G
R
P
S
S
K
E
G
R
R
S
Site 92
S735
P
G
P
G
R
P
S
S
K
E
G
R
R
S
D
Site 93
S741
S
S
K
E
G
R
R
S
D
T
C
E
Y
C
G
Site 94
T743
K
E
G
R
R
S
D
T
C
E
Y
C
G
K
V
Site 95
S755
G
K
V
F
K
N
C
S
N
L
T
V
H
R
R
Site 96
T758
F
K
N
C
S
N
L
T
V
H
R
R
S
H
T
Site 97
S763
N
L
T
V
H
R
R
S
H
T
G
E
R
P
Y
Site 98
T765
T
V
H
R
R
S
H
T
G
E
R
P
Y
K
C
Site 99
Y770
S
H
T
G
E
R
P
Y
K
C
E
L
C
N
Y
Site 100
Y777
Y
K
C
E
L
C
N
Y
A
C
A
Q
S
S
K
Site 101
T786
C
A
Q
S
S
K
L
T
R
H
M
K
T
H
G
Site 102
Y800
G
Q
V
G
K
D
V
Y
K
C
E
I
C
K
M
Site 103
S810
E
I
C
K
M
P
F
S
V
Y
S
T
L
E
K
Site 104
T814
M
P
F
S
V
Y
S
T
L
E
K
H
M
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation