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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CSRNP2
Full Name:
Cysteine/serine-rich nuclear protein 2
Alias:
Protein FAM130A1;TGF-beta-induced apoptosis protein 12
Type:
Mass (Da):
59591
Number AA:
543
UniProt ID:
Q9H175
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
F
D
D
V
D
V
G
S
S
V
S
N
S
D
D
Site 2
S21
D
D
V
D
V
G
S
S
V
S
N
S
D
D
E
Site 3
S23
V
D
V
G
S
S
V
S
N
S
D
D
E
I
S
Site 4
S25
V
G
S
S
V
S
N
S
D
D
E
I
S
S
S
Site 5
S30
S
N
S
D
D
E
I
S
S
S
D
S
A
D
S
Site 6
S31
N
S
D
D
E
I
S
S
S
D
S
A
D
S
C
Site 7
S32
S
D
D
E
I
S
S
S
D
S
A
D
S
C
D
Site 8
S34
D
E
I
S
S
S
D
S
A
D
S
C
D
S
L
Site 9
S37
S
S
S
D
S
A
D
S
C
D
S
L
N
P
P
Site 10
S40
D
S
A
D
S
C
D
S
L
N
P
P
T
T
A
Site 11
T45
C
D
S
L
N
P
P
T
T
A
S
F
T
P
T
Site 12
T46
D
S
L
N
P
P
T
T
A
S
F
T
P
T
S
Site 13
T50
P
P
T
T
A
S
F
T
P
T
S
I
L
K
R
Site 14
T52
T
T
A
S
F
T
P
T
S
I
L
K
R
Q
K
Site 15
S53
T
A
S
F
T
P
T
S
I
L
K
R
Q
K
Q
Site 16
Y74
R
F
D
Q
V
T
V
Y
Y
F
A
R
R
Q
G
Site 17
Y75
F
D
Q
V
T
V
Y
Y
F
A
R
R
Q
G
F
Site 18
T83
F
A
R
R
Q
G
F
T
S
V
P
S
Q
G
G
Site 19
S84
A
R
R
Q
G
F
T
S
V
P
S
Q
G
G
S
Site 20
S87
Q
G
F
T
S
V
P
S
Q
G
G
S
S
L
G
Site 21
S91
S
V
P
S
Q
G
G
S
S
L
G
M
A
Q
R
Site 22
S92
V
P
S
Q
G
G
S
S
L
G
M
A
Q
R
H
Site 23
S101
G
M
A
Q
R
H
N
S
V
R
S
Y
T
L
C
Site 24
Y105
R
H
N
S
V
R
S
Y
T
L
C
E
F
A
Q
Site 25
T106
H
N
S
V
R
S
Y
T
L
C
E
F
A
Q
E
Site 26
T143
M
K
L
T
K
N
G
T
V
E
S
V
E
A
D
Site 27
S146
T
K
N
G
T
V
E
S
V
E
A
D
G
L
T
Site 28
T153
S
V
E
A
D
G
L
T
L
D
D
V
S
D
E
Site 29
S158
G
L
T
L
D
D
V
S
D
E
D
I
D
V
E
Site 30
Y172
E
N
V
E
V
D
D
Y
F
F
L
Q
P
L
P
Site 31
T180
F
F
L
Q
P
L
P
T
K
R
R
R
A
L
L
Site 32
S190
R
R
A
L
L
R
A
S
G
V
H
R
I
D
A
Site 33
S209
E
L
R
A
I
R
L
S
R
E
E
C
G
C
D
Site 34
Y269
P
I
R
V
R
T
H
Y
L
H
T
I
M
K
L
Site 35
S280
I
M
K
L
E
L
E
S
K
R
Q
V
S
R
P
Site 36
S285
L
E
S
K
R
Q
V
S
R
P
A
A
P
D
E
Site 37
S295
A
A
P
D
E
E
P
S
P
T
A
S
C
S
L
Site 38
T297
P
D
E
E
P
S
P
T
A
S
C
S
L
T
G
Site 39
S299
E
E
P
S
P
T
A
S
C
S
L
T
G
A
Q
Site 40
S301
P
S
P
T
A
S
C
S
L
T
G
A
Q
G
S
Site 41
T303
P
T
A
S
C
S
L
T
G
A
Q
G
S
E
T
Site 42
S342
R
L
K
A
E
E
D
S
S
G
S
S
A
S
L
Site 43
S343
L
K
A
E
E
D
S
S
G
S
S
A
S
L
D
Site 44
S346
E
E
D
S
S
G
S
S
A
S
L
D
S
S
I
Site 45
S348
D
S
S
G
S
S
A
S
L
D
S
S
I
E
S
Site 46
S398
V
L
C
F
T
E
N
S
D
H
P
T
A
S
T
Site 47
T402
T
E
N
S
D
H
P
T
A
S
T
V
N
S
P
Site 48
S404
N
S
D
H
P
T
A
S
T
V
N
S
P
S
Y
Site 49
T405
S
D
H
P
T
A
S
T
V
N
S
P
S
Y
L
Site 50
S408
P
T
A
S
T
V
N
S
P
S
Y
L
N
S
G
Site 51
S410
A
S
T
V
N
S
P
S
Y
L
N
S
G
P
L
Site 52
Y411
S
T
V
N
S
P
S
Y
L
N
S
G
P
L
V
Site 53
S414
N
S
P
S
Y
L
N
S
G
P
L
V
Y
Y
Q
Site 54
Y420
N
S
G
P
L
V
Y
Y
Q
V
E
Q
R
P
V
Site 55
T436
G
V
K
G
E
P
G
T
E
E
G
S
A
S
F
Site 56
S442
G
T
E
E
G
S
A
S
F
P
K
E
K
D
L
Site 57
S473
D
P
A
A
L
C
K
S
E
V
G
K
T
P
T
Site 58
T478
C
K
S
E
V
G
K
T
P
T
L
E
A
L
L
Site 59
S502
E
N
E
D
F
H
P
S
W
S
P
S
S
L
P
Site 60
S504
E
D
F
H
P
S
W
S
P
S
S
L
P
F
R
Site 61
S506
F
H
P
S
W
S
P
S
S
L
P
F
R
T
D
Site 62
S507
H
P
S
W
S
P
S
S
L
P
F
R
T
D
N
Site 63
T512
P
S
S
L
P
F
R
T
D
N
E
E
G
C
G
Site 64
S524
G
C
G
M
V
K
T
S
Q
Q
N
E
D
R
P
Site 65
S535
E
D
R
P
P
E
D
S
S
L
E
L
P
L
A
Site 66
S536
D
R
P
P
E
D
S
S
L
E
L
P
L
A
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation