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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRPV6
Full Name:
Transient receptor potential cation channel subfamily V member 6
Alias:
Calcium transport protein 1; CaT1; CaT-L; CaT-like; ECaC2; Epithelial calcium channel 2; TrpV6
Type:
Plasma membrane, Integral plasma membrane protein
Mass (Da):
83210
Number AA:
725
UniProt ID:
Q9H1D0
International Prot ID:
IPI00152950
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005262
GO:0005509
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0017158
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
R
W
F
Q
R
R
E
S
W
A
Q
S
R
D
E
Site 2
S32
R
R
E
S
W
A
Q
S
R
D
E
Q
N
L
L
Site 3
S47
Q
Q
K
R
I
W
E
S
P
L
L
L
A
A
K
Site 4
Y67
A
L
N
K
L
L
K
Y
E
D
C
K
V
H
Q
Site 5
S112
L
V
F
E
P
M
T
S
E
L
Y
E
G
Q
T
Site 6
Y115
E
P
M
T
S
E
L
Y
E
G
Q
T
A
L
H
Site 7
S142
A
L
L
A
R
R
A
S
V
S
A
R
A
T
G
Site 8
S144
L
A
R
R
A
S
V
S
A
R
A
T
G
T
A
Site 9
T148
A
S
V
S
A
R
A
T
G
T
A
F
R
R
S
Site 10
T150
V
S
A
R
A
T
G
T
A
F
R
R
S
P
C
Site 11
S155
T
G
T
A
F
R
R
S
P
C
N
L
I
Y
F
Site 12
Y161
R
S
P
C
N
L
I
Y
F
G
E
H
P
L
S
Site 13
S194
A
D
I
R
A
Q
D
S
L
G
N
T
V
L
H
Site 14
Y222
M
Y
N
L
L
L
S
Y
D
R
H
G
D
H
L
Site 15
T266
L
M
Q
K
R
K
H
T
Q
W
T
Y
G
P
L
Site 16
T269
K
R
K
H
T
Q
W
T
Y
G
P
L
T
S
T
Site 17
Y270
R
K
H
T
Q
W
T
Y
G
P
L
T
S
T
L
Site 18
S275
W
T
Y
G
P
L
T
S
T
L
Y
D
L
T
E
Site 19
T276
T
Y
G
P
L
T
S
T
L
Y
D
L
T
E
I
Site 20
Y278
G
P
L
T
S
T
L
Y
D
L
T
E
I
D
S
Site 21
T281
T
S
T
L
Y
D
L
T
E
I
D
S
S
G
D
Site 22
S285
Y
D
L
T
E
I
D
S
S
G
D
E
Q
S
L
Site 23
S286
D
L
T
E
I
D
S
S
G
D
E
Q
S
L
L
Site 24
S291
D
S
S
G
D
E
Q
S
L
L
E
L
I
I
T
Site 25
T298
S
L
L
E
L
I
I
T
T
K
K
R
E
A
R
Site 26
T299
L
L
E
L
I
I
T
T
K
K
R
E
A
R
Q
Site 27
T311
A
R
Q
I
L
D
Q
T
P
V
K
E
L
V
S
Site 28
S318
T
P
V
K
E
L
V
S
L
K
W
K
R
Y
G
Site 29
Y324
V
S
L
K
W
K
R
Y
G
R
P
Y
F
C
M
Site 30
Y328
W
K
R
Y
G
R
P
Y
F
C
M
L
G
A
I
Site 31
T356
Y
R
P
L
K
P
R
T
N
N
R
T
S
P
R
Site 32
T360
K
P
R
T
N
N
R
T
S
P
R
D
N
T
L
Site 33
S361
P
R
T
N
N
R
T
S
P
R
D
N
T
L
L
Site 34
T366
R
T
S
P
R
D
N
T
L
L
Q
Q
K
L
L
Site 35
Y377
Q
K
L
L
Q
E
A
Y
M
T
P
K
D
D
I
Site 36
T379
L
L
Q
E
A
Y
M
T
P
K
D
D
I
R
L
Site 37
T514
A
F
Y
I
I
F
Q
T
E
D
P
E
E
L
G
Site 38
Y524
P
E
E
L
G
H
F
Y
D
Y
P
M
A
L
F
Site 39
Y526
E
L
G
H
F
Y
D
Y
P
M
A
L
F
S
T
Site 40
T601
R
A
Q
I
V
A
T
T
V
M
L
E
R
K
L
Site 41
Y623
S
G
I
C
G
R
E
Y
G
L
G
D
R
W
F
Site 42
S656
Q
A
F
H
T
R
G
S
E
D
L
D
K
D
S
Site 43
S663
S
E
D
L
D
K
D
S
V
E
K
L
E
L
G
Site 44
S683
H
L
S
L
P
M
P
S
V
S
R
S
T
S
R
Site 45
S685
S
L
P
M
P
S
V
S
R
S
T
S
R
S
S
Site 46
S687
P
M
P
S
V
S
R
S
T
S
R
S
S
A
N
Site 47
T688
M
P
S
V
S
R
S
T
S
R
S
S
A
N
W
Site 48
S689
P
S
V
S
R
S
T
S
R
S
S
A
N
W
E
Site 49
S691
V
S
R
S
T
S
R
S
S
A
N
W
E
R
L
Site 50
S692
S
R
S
T
S
R
S
S
A
N
W
E
R
L
R
Site 51
T702
W
E
R
L
R
Q
G
T
L
R
R
D
L
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation