KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WNT5B
Full Name:
Protein Wnt-5b
Alias:
Wingless-type MMTV integration site family, member 5B; Wnt-5b
Type:
Secreted protein. Ligand for members of the frizzled family of seven transmembrane receptors.
Mass (Da):
40323
Number AA:
359
UniProt ID:
Q9H1J7
International Prot ID:
IPI00022223
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007223
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
Q
L
L
T
D
A
N
S
W
W
S
L
A
L
N
Site 2
S55
C
S
Q
L
P
G
L
S
P
G
Q
R
K
L
C
Site 3
Y65
Q
R
K
L
C
Q
L
Y
Q
E
H
M
A
Y
I
Site 4
Y71
L
Y
Q
E
H
M
A
Y
I
G
E
G
A
K
T
Site 5
T78
Y
I
G
E
G
A
K
T
G
I
K
E
C
Q
H
Site 6
S95
R
Q
R
R
W
N
C
S
T
A
D
N
A
S
V
Site 7
S101
C
S
T
A
D
N
A
S
V
F
G
R
V
M
Q
Site 8
T114
M
Q
I
G
S
R
E
T
A
F
T
H
A
V
S
Site 9
T117
G
S
R
E
T
A
F
T
H
A
V
S
A
A
G
Site 10
S130
A
G
V
V
N
A
I
S
R
A
C
R
E
G
E
Site 11
S139
A
C
R
E
G
E
L
S
T
C
G
C
S
R
T
Site 12
T146
S
T
C
G
C
S
R
T
A
R
P
K
D
L
P
Site 13
Y167
G
C
G
D
N
V
E
Y
G
Y
R
F
A
K
E
Site 14
S189
E
K
N
F
A
K
G
S
E
E
Q
G
R
V
L
Site 15
Y210
E
A
G
R
R
A
V
Y
K
M
A
D
V
A
C
Site 16
S223
A
C
K
C
H
G
V
S
G
S
C
S
L
K
T
Site 17
S227
H
G
V
S
G
S
C
S
L
K
T
C
W
L
Q
Site 18
T230
S
G
S
C
S
L
K
T
C
W
L
Q
L
A
E
Site 19
Y249
G
D
R
L
K
E
K
Y
D
S
A
A
A
M
R
Site 20
S251
R
L
K
E
K
Y
D
S
A
A
A
M
R
V
T
Site 21
T258
S
A
A
A
M
R
V
T
R
K
G
R
L
E
L
Site 22
S268
G
R
L
E
L
V
N
S
R
F
T
Q
P
T
P
Site 23
T271
E
L
V
N
S
R
F
T
Q
P
T
P
E
D
L
Site 24
T274
N
S
R
F
T
Q
P
T
P
E
D
L
V
Y
V
Site 25
Y280
P
T
P
E
D
L
V
Y
V
D
P
S
P
D
Y
Site 26
S284
D
L
V
Y
V
D
P
S
P
D
Y
C
L
R
N
Site 27
Y287
Y
V
D
P
S
P
D
Y
C
L
R
N
E
S
T
Site 28
S293
D
Y
C
L
R
N
E
S
T
G
S
L
G
T
Q
Site 29
S296
L
R
N
E
S
T
G
S
L
G
T
Q
G
R
L
Site 30
T307
Q
G
R
L
C
N
K
T
S
E
G
M
D
G
C
Site 31
S308
G
R
L
C
N
K
T
S
E
G
M
D
G
C
E
Site 32
Y323
L
M
C
C
G
R
G
Y
N
Q
F
K
S
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation