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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OSBPL2
Full Name:
Oxysterol-binding protein-related protein 2
Alias:
Type:
Mass (Da):
55201
Number AA:
480
UniProt ID:
Q9H1P3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
E
E
F
F
D
A
V
T
G
F
D
S
D
N
S
Site 2
S16
D
A
V
T
G
F
D
S
D
N
S
S
G
E
F
Site 3
S19
T
G
F
D
S
D
N
S
S
G
E
F
S
E
A
Site 4
S20
G
F
D
S
D
N
S
S
G
E
F
S
E
A
N
Site 5
S24
D
N
S
S
G
E
F
S
E
A
N
Q
K
V
T
Site 6
T38
T
G
M
I
D
L
D
T
S
K
N
N
R
I
G
Site 7
S39
G
M
I
D
L
D
T
S
K
N
N
R
I
G
K
Site 8
T47
K
N
N
R
I
G
K
T
G
E
R
P
S
Q
E
Site 9
S52
G
K
T
G
E
R
P
S
Q
E
N
G
I
Q
K
Site 10
T62
N
G
I
Q
K
H
R
T
S
L
P
A
P
M
F
Site 11
S63
G
I
Q
K
H
R
T
S
L
P
A
P
M
F
S
Site 12
S70
S
L
P
A
P
M
F
S
R
S
D
F
S
V
W
Site 13
S72
P
A
P
M
F
S
R
S
D
F
S
V
W
T
I
Site 14
S75
M
F
S
R
S
D
F
S
V
W
T
I
L
K
K
Site 15
Y115
T
E
Y
M
E
H
V
Y
L
I
H
R
A
S
C
Site 16
S121
V
Y
L
I
H
R
A
S
C
Q
P
Q
P
L
E
Site 17
S143
F
A
V
S
A
V
A
S
Q
W
E
R
T
G
K
Site 18
S173
D
L
G
F
R
F
I
S
E
Q
V
S
H
H
P
Site 19
S177
R
F
I
S
E
Q
V
S
H
H
P
P
I
S
A
Site 20
S183
V
S
H
H
P
P
I
S
A
F
H
S
E
G
L
Site 21
S187
P
P
I
S
A
F
H
S
E
G
L
N
H
D
F
Site 22
S210
K
L
K
F
W
G
K
S
V
E
A
E
P
R
G
Site 23
T218
V
E
A
E
P
R
G
T
I
T
L
E
L
L
K
Site 24
T220
A
E
P
R
G
T
I
T
L
E
L
L
K
H
N
Site 25
Y252
G
K
L
W
I
E
Q
Y
G
T
V
E
I
L
N
Site 26
T254
L
W
I
E
Q
Y
G
T
V
E
I
L
N
H
R
Site 27
S313
L
W
G
I
D
P
V
S
Y
E
S
F
K
K
Q
Site 28
Y314
W
G
I
D
P
V
S
Y
E
S
F
K
K
Q
E
Site 29
S316
I
D
P
V
S
Y
E
S
F
K
K
Q
E
R
R
Site 30
S336
K
A
K
L
D
E
D
S
G
K
A
D
S
D
V
Site 31
S341
E
D
S
G
K
A
D
S
D
V
A
D
D
V
P
Site 32
T368
K
L
L
W
R
I
N
T
R
P
P
N
S
A
Q
Site 33
Y377
P
P
N
S
A
Q
M
Y
N
F
T
S
F
T
V
Site 34
S381
A
Q
M
Y
N
F
T
S
F
T
V
S
L
N
E
Site 35
S385
N
F
T
S
F
T
V
S
L
N
E
L
E
T
G
Site 36
T396
L
E
T
G
M
E
K
T
L
P
P
T
D
C
R
Site 37
T400
M
E
K
T
L
P
P
T
D
C
R
L
R
P
D
Site 38
S420
N
G
N
M
D
L
A
S
Q
E
K
E
R
L
E
Site 39
T457
Y
P
G
N
N
P
Y
T
G
T
P
D
W
L
Y
Site 40
T459
G
N
N
P
Y
T
G
T
P
D
W
L
Y
A
G
Site 41
Y464
T
G
T
P
D
W
L
Y
A
G
D
Y
F
E
R
Site 42
Y468
D
W
L
Y
A
G
D
Y
F
E
R
N
F
S
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation