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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCG5
Full Name:
ATP-binding cassette sub-family G member 5
Alias:
Sterolin-1
Type:
Mass (Da):
72504
Number AA:
651
UniProt ID:
Q9H222
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
G
D
L
S
S
L
T
P
G
G
S
Site 2
S6
_
_
M
G
D
L
S
S
L
T
P
G
G
S
M
Site 3
S12
S
S
L
T
P
G
G
S
M
G
L
Q
V
N
R
Site 4
S21
G
L
Q
V
N
R
G
S
Q
S
S
L
E
G
A
Site 5
S24
V
N
R
G
S
Q
S
S
L
E
G
A
P
A
T
Site 6
T31
S
L
E
G
A
P
A
T
A
P
E
P
H
S
L
Site 7
S37
A
T
A
P
E
P
H
S
L
G
I
L
H
A
S
Site 8
Y45
L
G
I
L
H
A
S
Y
S
V
S
H
R
V
R
Site 9
S46
G
I
L
H
A
S
Y
S
V
S
H
R
V
R
P
Site 10
S73
R
Q
I
L
K
D
V
S
L
Y
V
E
S
G
Q
Site 11
T94
S
S
G
S
G
K
T
T
L
L
D
A
M
S
G
Site 12
S100
T
T
L
L
D
A
M
S
G
R
L
G
R
A
G
Site 13
Y131
Q
F
Q
D
C
F
S
Y
V
L
Q
S
D
T
L
Site 14
S141
Q
S
D
T
L
L
S
S
L
T
V
R
E
T
L
Site 15
T143
D
T
L
L
S
S
L
T
V
R
E
T
L
H
Y
Site 16
S163
I
R
R
G
N
P
G
S
F
Q
K
K
V
E
A
Site 17
Y188
A
D
R
L
I
G
N
Y
S
L
G
G
I
S
T
Site 18
S189
D
R
L
I
G
N
Y
S
L
G
G
I
S
T
G
Site 19
T195
Y
S
L
G
G
I
S
T
G
E
R
R
R
V
S
Site 20
S202
T
G
E
R
R
R
V
S
I
A
A
Q
L
L
Q
Site 21
T248
R
N
R
I
V
V
L
T
I
H
Q
P
R
S
E
Site 22
S254
L
T
I
H
Q
P
R
S
E
L
F
Q
L
F
D
Site 23
Y301
H
S
N
P
F
D
F
Y
M
D
L
T
S
V
D
Site 24
T305
F
D
F
Y
M
D
L
T
S
V
D
T
Q
S
K
Site 25
S306
D
F
Y
M
D
L
T
S
V
D
T
Q
S
K
E
Site 26
T309
M
D
L
T
S
V
D
T
Q
S
K
E
R
E
I
Site 27
S311
L
T
S
V
D
T
Q
S
K
E
R
E
I
E
T
Site 28
S319
K
E
R
E
I
E
T
S
K
R
V
Q
M
I
E
Site 29
S327
K
R
V
Q
M
I
E
S
A
Y
K
K
S
A
I
Site 30
S332
I
E
S
A
Y
K
K
S
A
I
C
H
K
T
L
Site 31
T338
K
S
A
I
C
H
K
T
L
K
N
I
E
R
M
Site 32
T350
E
R
M
K
H
L
K
T
L
P
M
V
P
F
K
Site 33
S361
V
P
F
K
T
K
D
S
P
G
V
F
S
K
L
Site 34
T376
G
V
L
L
R
R
V
T
R
N
L
V
R
N
K
Site 35
S449
F
P
V
L
R
A
V
S
D
Q
E
S
Q
D
G
Site 36
S453
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
Q
K
Site 37
Y458
Q
E
S
Q
D
G
L
Y
Q
K
W
Q
M
M
L
Site 38
T586
E
F
Y
G
L
N
F
T
C
G
S
S
N
V
S
Site 39
S593
T
C
G
S
S
N
V
S
V
T
T
N
P
M
C
Site 40
T612
G
I
Q
F
I
E
K
T
C
P
G
A
T
S
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation