PhosphoNET

           
Protein Info 
   
Short Name:  PORCN
Full Name:  Probable protein-cysteine N-palmitoyltransferase porcupine
Alias:  Protein MG61
Type: 
Mass (Da):  52318
Number AA:  461
UniProt ID:  Q9H237
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S49LWRLGLPSYLKHAST
Site 2Y50WRLGLPSYLKHASTV
Site 3S92VLFLCRHSSHRGVFL
Site 4S93LFLCRHSSHRGVFLS
Site 5S100SHRGVFLSVTILIYL
Site 6T148LDRGEVGTVPSPVEF
Site 7Y176PWISFHSYLQAVQGR
Site 8S186AVQGRPLSCRWLQKV
Site 9T237KKRKARGTMVRWLRA
Site 10Y245MVRWLRAYESAVSFH
Site 11S247RWLRAYESAVSFHFS
Site 12S250RAYESAVSFHFSNYF
Site 13T285DHLEWDLTVSKPLNV
Site 14Y316MSYWLNNYVFKNALR
Site 15T424FDVDVDDTTEEQGYG
Site 16T425DVDVDDTTEEQGYGM
Site 17Y430DTTEEQGYGMAYTVH
Site 18Y434EQGYGMAYTVHKWSE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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