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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMP28
Full Name:
Matrix metalloproteinase-28
Alias:
Epilysin
Type:
Mass (Da):
58939
Number AA:
520
UniProt ID:
Q9H239
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y43
A
E
A
F
L
E
K
Y
G
Y
L
N
E
Q
V
Site 2
Y45
A
F
L
E
K
Y
G
Y
L
N
E
Q
V
P
K
Site 3
S56
Q
V
P
K
A
P
T
S
T
R
F
S
D
A
I
Site 4
S60
A
P
T
S
T
R
F
S
D
A
I
R
A
F
Q
Site 5
S70
I
R
A
F
Q
W
V
S
Q
L
P
V
S
G
V
Site 6
T82
S
G
V
L
D
R
A
T
L
R
Q
M
T
R
P
Site 7
T87
R
A
T
L
R
Q
M
T
R
P
R
C
G
V
T
Site 8
T94
T
R
P
R
C
G
V
T
D
T
N
S
Y
A
A
Site 9
S107
A
A
W
A
E
R
I
S
D
L
F
A
R
H
R
Site 10
T115
D
L
F
A
R
H
R
T
K
M
R
R
K
K
R
Site 11
Y131
A
K
Q
G
N
K
W
Y
K
Q
H
L
S
Y
R
Site 12
T176
E
F
W
E
A
P
A
T
G
P
A
D
I
R
L
Site 13
T184
G
P
A
D
I
R
L
T
F
F
Q
G
D
H
N
Site 14
S225
F
D
Q
D
E
R
W
S
L
S
R
R
R
G
R
Site 15
S227
Q
D
E
R
W
S
L
S
R
R
R
G
R
N
L
Site 16
T245
L
A
H
E
I
G
H
T
L
G
L
T
H
S
P
Site 17
T249
I
G
H
T
L
G
L
T
H
S
P
A
P
R
A
Site 18
S251
H
T
L
G
L
T
H
S
P
A
P
R
A
L
M
Site 19
Y261
P
R
A
L
M
A
P
Y
Y
K
R
L
G
R
D
Site 20
Y262
R
A
L
M
A
P
Y
Y
K
R
L
G
R
D
A
Site 21
T305
K
L
F
T
D
F
E
T
W
D
S
Y
S
P
Q
Site 22
S308
T
D
F
E
T
W
D
S
Y
S
P
Q
G
R
R
Site 23
Y309
D
F
E
T
W
D
S
Y
S
P
Q
G
R
R
P
Site 24
S310
F
E
T
W
D
S
Y
S
P
Q
G
R
R
P
E
Site 25
T318
P
Q
G
R
R
P
E
T
Q
G
P
K
Y
C
H
Site 26
Y323
P
E
T
Q
G
P
K
Y
C
H
S
S
F
D
A
Site 27
S326
Q
G
P
K
Y
C
H
S
S
F
D
A
I
T
V
Site 28
S327
G
P
K
Y
C
H
S
S
F
D
A
I
T
V
D
Site 29
T332
H
S
S
F
D
A
I
T
V
D
R
Q
Q
Q
L
Site 30
Y340
V
D
R
Q
Q
Q
L
Y
I
F
K
G
S
H
F
Site 31
Y386
S
L
N
D
G
D
F
Y
F
F
K
G
G
R
C
Site 32
Y451
G
G
L
Q
V
E
P
Y
Y
P
R
S
L
Q
D
Site 33
Y452
G
L
Q
V
E
P
Y
Y
P
R
S
L
Q
D
W
Site 34
S455
V
E
P
Y
Y
P
R
S
L
Q
D
W
G
G
I
Site 35
Y485
I
F
F
R
D
D
R
Y
W
R
L
D
Q
A
K
Site 36
S498
A
K
L
Q
A
T
T
S
G
R
W
A
T
E
L
Site 37
T503
T
T
S
G
R
W
A
T
E
L
P
W
M
G
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation