KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
P2RY12
Full Name:
P2Y purinoceptor 12
Alias:
ADP-glucose receptor;P2T(AC);P2Y(AC);P2Y(cyc);P2Y12 platelet ADP receptor;SP1999
Type:
Mass (Da):
39439
Number AA:
342
UniProt ID:
Q9H244
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
Q
A
V
D
N
L
T
S
A
P
G
N
T
S
Site 2
S15
T
S
A
P
G
N
T
S
L
C
T
R
D
Y
K
Site 3
S55
R
I
F
F
Q
I
R
S
K
S
N
F
I
I
F
Site 4
S57
F
F
Q
I
R
S
K
S
N
F
I
I
F
L
K
Site 5
T66
F
I
I
F
L
K
N
T
V
I
S
D
L
L
M
Site 6
S69
F
L
K
N
T
V
I
S
D
L
L
M
I
L
T
Site 7
T76
S
D
L
L
M
I
L
T
F
P
F
K
I
L
S
Site 8
Y105
Q
V
T
S
V
I
F
Y
F
T
M
Y
I
S
I
Site 9
T107
T
S
V
I
F
Y
F
T
M
Y
I
S
I
S
F
Site 10
Y123
G
L
I
T
I
D
R
Y
Q
K
T
T
R
P
F
Site 11
T126
T
I
D
R
Y
Q
K
T
T
R
P
F
K
T
S
Site 12
T127
I
D
R
Y
Q
K
T
T
R
P
F
K
T
S
N
Site 13
T132
K
T
T
R
P
F
K
T
S
N
P
K
N
L
L
Site 14
S133
T
T
R
P
F
K
T
S
N
P
K
N
L
L
G
Site 15
T163
S
L
P
N
M
I
L
T
N
R
Q
P
R
D
K
Site 16
S176
D
K
N
V
K
K
C
S
F
L
K
S
E
F
G
Site 17
Y217
T
L
I
T
K
E
L
Y
R
S
Y
V
R
T
R
Site 18
S219
I
T
K
E
L
Y
R
S
Y
V
R
T
R
G
V
Site 19
Y220
T
K
E
L
Y
R
S
Y
V
R
T
R
G
V
G
Site 20
T223
L
Y
R
S
Y
V
R
T
R
G
V
G
K
V
P
Site 21
Y259
F
H
F
A
R
I
P
Y
T
L
S
Q
T
R
D
Site 22
T260
H
F
A
R
I
P
Y
T
L
S
Q
T
R
D
V
Site 23
S262
A
R
I
P
Y
T
L
S
Q
T
R
D
V
F
D
Site 24
T264
I
P
Y
T
L
S
Q
T
R
D
V
F
D
C
T
Site 25
T271
T
R
D
V
F
D
C
T
A
E
N
T
L
F
Y
Site 26
Y278
T
A
E
N
T
L
F
Y
V
K
E
S
T
L
W
Site 27
S311
S
F
R
N
S
L
I
S
M
L
K
C
P
N
S
Site 28
S318
S
M
L
K
C
P
N
S
A
T
S
L
S
Q
D
Site 29
S321
K
C
P
N
S
A
T
S
L
S
Q
D
N
R
K
Site 30
S323
P
N
S
A
T
S
L
S
Q
D
N
R
K
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation