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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDH23
Full Name:
Cadherin-23
Alias:
CAD23; Cadherin 23 C1; Cadherin 23 C2; Cadherin related 23; Cadherin-like 23; DFNB12; Otocadherin; USH1D
Type:
Adhesion
Mass (Da):
369525
Number AA:
3354
UniProt ID:
Q9H251
International Prot ID:
IPI00216560
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
GO:0032420
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016339
GO:0050957
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T1226
R
E
T
A
G
I
G
T
S
V
I
V
V
Q
A
Site 2
Y1246
G
D
G
G
L
V
N
Y
R
I
L
S
G
A
E
Site 3
Y1348
D
N
L
N
Q
I
T
Y
R
F
D
A
Y
T
S
Site 4
Y1353
I
T
Y
R
F
D
A
Y
T
S
T
Q
A
K
A
Site 5
Y1672
G
P
N
G
T
V
T
Y
A
I
V
A
G
N
I
Site 6
S2259
A
T
Y
E
V
T
L
S
V
I
D
N
A
S
D
Site 7
S2271
A
S
D
L
P
E
R
S
V
S
V
P
N
A
K
Site 8
T2280
S
V
P
N
A
K
L
T
V
N
V
L
D
V
N
Site 9
T2290
V
L
D
V
N
D
N
T
P
Q
F
K
P
F
G
Site 10
Y2633
I
P
L
R
S
N
V
Y
E
V
Y
A
T
D
K
Site 11
Y2636
R
S
N
V
Y
E
V
Y
A
T
D
K
D
E
G
Site 12
Y2650
G
L
N
G
A
V
R
Y
S
F
L
K
T
A
G
Site 13
S2729
F
V
R
P
P
K
G
S
P
Q
Y
Q
L
L
T
Site 14
Y2732
P
P
K
G
S
P
Q
Y
Q
L
L
T
V
P
E
Site 15
T2736
S
P
Q
Y
Q
L
L
T
V
P
E
H
S
P
R
Site 16
S2741
L
L
T
V
P
E
H
S
P
R
G
T
L
V
G
Site 17
Y3089
L
F
V
L
M
N
W
Y
Y
R
T
V
H
K
R
Site 18
Y3090
F
V
L
M
N
W
Y
Y
R
T
V
H
K
R
K
Site 19
Y3123
D
M
P
N
T
N
K
Y
S
F
D
G
A
N
P
Site 20
S3124
M
P
N
T
N
K
Y
S
F
D
G
A
N
P
V
Site 21
S3157
D
D
L
P
E
N
L
S
E
I
A
D
L
W
N
Site 22
S3165
E
I
A
D
L
W
N
S
P
T
R
T
H
G
T
Site 23
T3167
A
D
L
W
N
S
P
T
R
T
H
G
T
F
G
Site 24
T3169
L
W
N
S
P
T
R
T
H
G
T
F
G
R
E
Site 25
T3172
S
P
T
R
T
H
G
T
F
G
R
E
P
A
A
Site 26
Y3187
V
K
P
D
D
D
R
Y
L
R
A
A
I
Q
E
Site 27
Y3195
L
R
A
A
I
Q
E
Y
D
N
I
A
K
L
G
Site 28
S3238
Q
R
M
V
Q
K
A
S
S
C
H
S
S
I
S
Site 29
S3239
R
M
V
Q
K
A
S
S
C
H
S
S
I
S
E
Site 30
S3242
Q
K
A
S
S
C
H
S
S
I
S
E
L
I
Q
Site 31
S3243
K
A
S
S
C
H
S
S
I
S
E
L
I
Q
T
Site 32
S3245
S
S
C
H
S
S
I
S
E
L
I
Q
T
E
L
Site 33
T3250
S
I
S
E
L
I
Q
T
E
L
D
E
E
P
G
Site 34
S3260
D
E
E
P
G
D
H
S
P
G
Q
G
S
L
R
Site 35
S3265
D
H
S
P
G
Q
G
S
L
R
F
R
H
K
P
Site 36
T3295
S
T
G
T
L
L
A
T
D
L
N
S
L
P
E
Site 37
S3299
L
L
A
T
D
L
N
S
L
P
E
E
D
Q
K
Site 38
S3311
D
Q
K
G
L
G
R
S
L
E
T
L
T
A
A
Site 39
S3331
E
R
N
A
R
T
E
S
A
K
S
T
P
L
H
Site 40
S3334
A
R
T
E
S
A
K
S
T
P
L
H
K
L
R
Site 41
T3335
R
T
E
S
A
K
S
T
P
L
H
K
L
R
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation